3FCX | | CRYSTAL STRUCTURE OF HUMAN ESTERASE D | | Descriptor: | S-formylglutathione hydrolase, MAGNESIUM ION, CALCIUM ION | | Authors: | Wu, D., Li, Y., Song, G., Zhang, D., Shaw, N., Liu, Z.J. | | Deposit date: | 2008-11-24 | | Release date: | 2008-12-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of human esterase D: a potential genetic marker of retinoblastoma
Faseb J., 23, 2009
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1NM8 | | STRUCTURE OF HUMAN CARNITINE ACETYLTRANSFERASE: MOLECULAR BASIS FOR FATTY ACYL TRANSFER | | Descriptor: | Carnitine O-acetyltransferase | | Authors: | Wu, D., Govindasamy, L., Lian, W., Gu, Y., Kukar, T., Agbandje-McKenna, M., McKenna, R. | | Deposit date: | 2003-01-09 | | Release date: | 2003-03-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure of Human Carnitine Acetyltransferase. Molecular Basis for Fatty Acyl Transfer
J.Biol.Chem., 278, 2003
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2FIK | | STRUCTURE OF A MICROBIAL GLYCOSPHINGOLIPID BOUND TO MOUSE CD1D | | Descriptor: | T-cell surface glycoprotein CD1d1, B(2)-microglobulin, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Wu, D., Zajonc, D.M. | | Deposit date: | 2005-12-29 | | Release date: | 2006-03-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2PVP | |
2RJG | | CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE FROM ESCHERICHIA COLI | | Descriptor: | Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X. | | Deposit date: | 2007-10-15 | | Release date: | 2008-07-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
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2RJH | | CRYSTAL STRUCTURE OF BIOSYNTHETIC ALAINE RACEMASE IN D-CYCLOSERINE-BOUND FORM FROM ESCHERICHIA COLI | | Descriptor: | Alanine racemase, SULFATE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE | | Authors: | Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X. | | Deposit date: | 2007-10-15 | | Release date: | 2008-07-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
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3B8T | | CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT P219A | | Descriptor: | Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X. | | Deposit date: | 2007-11-02 | | Release date: | 2008-07-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
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3B8U | | CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221A | | Descriptor: | Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X. | | Deposit date: | 2007-11-02 | | Release date: | 2008-07-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
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3B8V | | CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221K | | Descriptor: | Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X. | | Deposit date: | 2007-11-02 | | Release date: | 2008-07-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
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3B8W | | CRYSTAL STRUCTURE OF ESCHERICHIA COLI ALAINE RACEMASE MUTANT E221P | | Descriptor: | Alanine racemase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Wu, D., Hu, T., Zhang, L., Jiang, H., Shen, X. | | Deposit date: | 2007-11-02 | | Release date: | 2008-07-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis
Protein Sci., 17, 2008
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3HXT | | STRUCTURE OF HUMAN MTHFS | | Descriptor: | 5-formyltetrahydrofolate cyclo-ligase, NICKEL (II) ION, MAGNESIUM ION | | Authors: | Wu, D., Li, Y., Song, G., Cheng, C., Zhang, R., Joachimiak, A., Shaw, N., Liu, Z.-J. | | Deposit date: | 2009-06-22 | | Release date: | 2009-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
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3HY3 | | STRUCTURE OF HUMAN MTHFS WITH 10-FORMYLTETRAHYDROFOLATE | | Descriptor: | 5-formyltetrahydrofolate cyclo-ligase, N-({4-[{[(2R,4S,4aR,6S,8aS)-2-amino-4-hydroxydecahydropteridin-6-yl]methyl}(formyl)amino]phenyl}carbonyl)-D-glutamic acid, NICKEL (II) ION, ... | | Authors: | Wu, D., Li, Y., Song, G., Cheng, C., Shaw, N., Liu, Z.-J. | | Deposit date: | 2009-06-22 | | Release date: | 2009-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
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3HY4 | | STRUCTURE OF HUMAN MTHFS WITH N5-IMINIUM PHOSPHATE | | Descriptor: | 5-formyltetrahydrofolate cyclo-ligase, NICKEL (II) ION, MAGNESIUM ION, ... | | Authors: | Wu, D., Li, Y., Song, G., Cheng, C., Shaw, N., Liu, Z.-J. | | Deposit date: | 2009-06-22 | | Release date: | 2009-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.795 Å) | | Cite: | Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
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3HY6 | | STRUCTURE OF HUMAN MTHFS WITH ADP | | Descriptor: | 5-formyltetrahydrofolate cyclo-ligase, NICKEL (II) ION, MAGNESIUM ION, ... | | Authors: | Wu, D., Li, Y., Song, G., Cheng, C., Shaw, N., Liu, Z.-J. | | Deposit date: | 2009-06-22 | | Release date: | 2009-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for the inhibition of human 5,10-methenyltetrahydrofolate synthetase by N10-substituted folate analogues
Cancer Res., 69, 2009
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4DNU | | CRYSTAL STRUCTURE OF THE W285A MUTANT OF UVB-RESISTANCE PROTEIN UVR8 | | Descriptor: | AT5g63860/MGI19_6 | | Authors: | Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Zhang, J., Wang, J., Shi, Y. | | Deposit date: | 2012-02-09 | | Release date: | 2012-03-07 | | Last modified: | 2013-07-17 | | Method: | X-RAY DIFFRACTION (1.764 Å) | | Cite: | Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
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4DNV | | CRYSTAL STRUCTURE OF THE W285F MUTANT OF UVB-RESISTANCE PROTEIN UVR8 | | Descriptor: | AT5g63860/MGI19_6 | | Authors: | Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Zhang, J., Wang, J., Shi, Y. | | Deposit date: | 2012-02-09 | | Release date: | 2012-03-07 | | Last modified: | 2013-07-17 | | Method: | X-RAY DIFFRACTION (1.999 Å) | | Cite: | Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
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4DNW | | CRYSTAL STRUCTURE OF UVB-RESISTANCE PROTEIN UVR8 | | Descriptor: | AT5g63860/MGI19_6 | | Authors: | Wu, D., Hu, Q., Yan, Z., Chen, W., Yan, C., Wang, J., Shi, Y. | | Deposit date: | 2012-02-09 | | Release date: | 2012-03-07 | | Last modified: | 2013-07-17 | | Method: | X-RAY DIFFRACTION (1.773 Å) | | Cite: | Structural basis of ultraviolet-B perception by UVR8.
Nature, 484, 2012
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4M4X | |
4YLW | | CRYSTAL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE (DHODH) WITH NO.33 COMPOUND | | Descriptor: | Dihydroorotate dehydrogenase (quinone), mitochondrial, methyl (2Z)-cyano[3-(3-fluoro-4'-methoxybiphenyl-4-yl)-4-oxo-1,3-thiazolidin-2-ylidene]acetate, ... | | Authors: | Wu, D., Ouyang, P., Lu, W., Huang, J. | | Deposit date: | 2015-03-06 | | Release date: | 2016-03-09 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with No.33 compound
To Be Published
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4ZP4 | | CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2A:ARNT COMPLEX | | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 | | Authors: | Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F. | | Deposit date: | 2015-05-07 | | Release date: | 2015-08-12 | | Last modified: | 2015-08-26 | | Method: | X-RAY DIFFRACTION (2.355 Å) | | Cite: | Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
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4ZPH | | CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2A:ARNT COMPLEX WITH PROFLAVINE | | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, PROFLAVIN | | Authors: | Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F. | | Deposit date: | 2015-05-07 | | Release date: | 2015-08-12 | | Last modified: | 2015-08-26 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
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4ZPK | | CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2A:ARNT COMPLEX WITH HRE DNA | | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ... | | Authors: | Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F. | | Deposit date: | 2015-05-08 | | Release date: | 2015-08-12 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
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4ZPR | | CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-1A:ARNT COMPLEX WITH HRE DNA | | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Hypoxia-inducible factor 1-alpha, DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ... | | Authors: | Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F. | | Deposit date: | 2015-05-08 | | Release date: | 2015-08-12 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (3.902 Å) | | Cite: | Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
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4ZQD | | CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2A:ARNT COMPLEX WITH THE BENZOXADIAZOLE ANTAGONIST 0X3 | | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine | | Authors: | Wu, D., Potluri, N., Lu, J., Kim, Y., Rastinejad, F. | | Deposit date: | 2015-05-09 | | Release date: | 2015-08-12 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.87 Å) | | Cite: | Structural integration in hypoxia-inducible factors.
Nature, 524, 2015
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5BXJ | | COMPLEX OF THE FK1 DOMAIN MUTANT A19T OF FKBP51 WITH 4-NITROPHENOL | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP5, P-NITROPHENOL | | Authors: | Wu, D., Tao, X., Chen, Z., Han, J., Jia, W., Li, X., Wang, Z., He, Y.X. | | Deposit date: | 2015-06-09 | | Release date: | 2016-05-25 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells
J. Hazard. Mater., 307, 2016
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