Author results

2ROV
  • Download 2rov
  • View 2rov
Molmil generated image of 2rov
THE SPLIT PH DOMAIN OF ROCK II
Descriptor:Rho-associated protein kinase 2
Authors:Wen, W., Zhang, M.
Deposit date:2008-04-25
Release date:2008-06-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The split PH domain of ROCK II
To be Published
2ROW
  • Download 2row
  • View 2row
Molmil generated image of 2row
THE C1 DOMAIN OF ROCK II
Descriptor:Rho-associated protein kinase 2, ZINC ION
Authors:Wen, W., Zhang, M.
Deposit date:2008-04-25
Release date:2008-06-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The C1 domain of ROCK II
To be Published
2FJL
  • Download 2fjl
  • View 2fjl
Molmil generated image of 2fjl
SOLUTION STRUCTURE OF THE SPLIT PH DOMAIN IN PHOSPHOLIPASE C-GAMMA1
Descriptor:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
Authors:Wen, W., Zhang, M.
Deposit date:2006-01-03
Release date:2006-03-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Characterization of the Split Pleckstrin Homology Domain in Phospholipase C-{gamma}1 and Its Interaction with TRPC3
J.Biol.Chem., 281, 2006
2FZ0
  • Download 2fz0
  • View 2fz0
Molmil generated image of 2fz0
IDENTIFICATION OF YEAST R-SNARE NYV1P AS A NOVEL LONGIN DOMAIN PROTEIN
Descriptor:v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane; Nyv1p
Authors:Wen, W., Zhang, M.
Deposit date:2006-02-08
Release date:2006-03-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Identification of the Yeast R-SNARE Nyv1p as a Novel Longin Domain-containing Protein
Mol.Cell.Biol., 17, 2006
2KXR
  • Download 2kxr
  • View 2kxr
Molmil generated image of 2kxr
ZO1 ZU5 DOMAIN MC/AA MUTATION
Descriptor:Tight junction protein ZO-1
Authors:Wen, W., Zhang, M.
Deposit date:2010-05-12
Release date:2011-03-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration
Embo J., 30, 2011
2KXS
  • Download 2kxs
  • View 2kxs
Molmil generated image of 2kxs
ZO1 ZU5 DOMAIN IN COMPLEX WITH GRINL1A PEPTIDE
Descriptor:Tight junction protein ZO-1, LINKER, peptide of Myocardium-enriched Zo-associated protein
Authors:Wen, W., Zhang, M.
Deposit date:2010-05-12
Release date:2011-03-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration
Embo J., 30, 2011
2RLO
  • Download 2rlo
  • View 2rlo
Molmil generated image of 2rlo
SPLIT PH DOMAIN OF PI3-KINASE ENHANCER
Descriptor:Centaurin-gamma 1
Authors:Wen, W., Zhang, M.
Deposit date:2007-07-21
Release date:2008-04-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Split pleckstrin homology domain-mediated cytoplasmic-nuclear localization of PI3-kinase enhancer GTPase
J.Mol.Biol., 378, 2008
4G5S
  • Download 4g5s
  • View 4g5s
Molmil generated image of 4g5s
STRUCTURE OF LGN GL3/GALPHAI3 COMPLEX
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
1Z86
  • Download 1z86
  • View 1z86
Molmil generated image of 1z86
SOLUTION STRUCTURE OF THE PDZ DOMAIN OF ALPHA-SYNTROPHIN
Descriptor:Alpha-1-syntrophin
Authors:Yan, J., Xu, W., Wen, W., Long, J.F., Adams, M.E., Froehner, S.C., Zhang, M.
Deposit date:2005-03-30
Release date:2006-01-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
1Z87
  • Download 1z87
  • View 1z87
Molmil generated image of 1z87
SOLUTION STRUCTURE OF THE SPLIT PH-PDZ SUPRAMODULE OF ALPHA-SYNTROPHIN
Descriptor:Alpha-1-syntrophin
Authors:Yan, J., Xu, W., Wen, W., Long, J.F., Adams, M.E., Froehner, S.C., Zhang, M.
Deposit date:2005-03-30
Release date:2006-01-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
2ADZ
  • Download 2adz
  • View 2adz
Molmil generated image of 2adz
SOLUTION STRUCTURE OF THE JOINED PH DOMAIN OF ALPHA1-SYNTROPHIN
Descriptor:Alpha-1-syntrophin
Authors:Yan, J., Wen, W., Xu, W., Long, J.F., Adams, M.E., Froehner, S.C., Zhang, M.
Deposit date:2005-07-21
Release date:2006-01-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
3RO3
  • Download 3ro3
  • View 3ro3
Molmil generated image of 3ro3
CRYSTAL STRUCTURE OF LGN/MINSCUTEABLE COMPLEX
Descriptor:G-protein-signaling modulator 2, peptide of Protein inscuteable homolog, GLYCEROL, ...
Authors:Zhu, J., Wen, W., Shang, Y., Wei, Z., Pan, Z., Wang, W., Zhang, M.
Deposit date:2011-04-25
Release date:2012-03-07
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Mol.Cell, 43, 2011
4G2V
  • Download 4g2v
  • View 4g2v
Molmil generated image of 4g2v
STRUCTURE COMPLEX OF LGN BINDING WITH FRMPD1
Descriptor:G-protein-signaling modulator 2, peptide from FERM and PDZ domain-containing protein 1, GLYCEROL, ...
Authors:Shang, Y., Pan, Z., Wen, W., Wang, W., Zhang, M.
Deposit date:2012-07-13
Release date:2013-01-23
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and biochemical characterization of the interaction between LGN and Frmpd1
J.Mol.Biol., 425, 2013
4G5O
  • Download 4g5o
  • View 4g5o
Molmil generated image of 4g5o
STRUCTURE OF LGN GL4/GALPHAI3(Q147L) COMPLEX
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4G5Q
  • Download 4g5q
  • View 4g5q
Molmil generated image of 4g5q
STRUCTURE OF LGN GL4/GALPHAI1 COMPLEX
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4G5R
  • Download 4g5r
  • View 4g5r
Molmil generated image of 4g5r
STRUCTURE OF LGN GL4/GALPHAI3 COMPLEX
Descriptor:Guanine nucleotide-binding protein G(k) subunit alpha, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Jia, M., Li, J., Zhu, J., Wen, W., Zhang, M., Wang, W.
Deposit date:2012-07-18
Release date:2012-09-05
Method:X-RAY DIFFRACTION (3.481 Å)
Cite:Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
4JHR
  • Download 4jhr
  • View 4jhr
Molmil generated image of 4jhr
AN AUTO-INHIBITED CONFORMATION OF LGN REVEALS A DISTINCT INTERACTION MODE BETWEEN GOLOCO MOTIFS AND TPR MOTIFS
Descriptor:G-protein-signaling modulator 2
Authors:Pan, Z., Zhu, J., Shang, Y., Wei, Z., Jia, M., Xia, C., Wen, W., Wang, W., Zhang, M.
Deposit date:2013-03-05
Release date:2013-06-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs
Structure, 21, 2013
2LA8
  • Download 2la8
  • View 2la8
Molmil generated image of 2la8
SOLUTION STRUCTURE OF INAD PDZ5 COMPLEXED WITH KON-TIKI PEPTIDE
Descriptor:Inactivation-no-after-potential D protein, Kon-tiki peptide
Authors:Zhang, M., Wen, W.
Deposit date:2011-03-08
Release date:2011-11-30
Method:SOLUTION NMR
Cite:The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye
Cell(Cambridge,Mass.), 145, 2011
2M0Y
  • Download 2m0y
  • View 2m0y
Molmil generated image of 2m0y
SOLUTION STRUCTURE OF THE SH3 DOMAIN OF DOCK180
Descriptor:Dedicator of cytokinesis protein 1
Authors:Liu, X., Wen, W.
Deposit date:2012-11-08
Release date:2012-12-19
Last modified:2013-04-24
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain of DOCK180.
Proteins, 81, 2013
3UAT
  • Download 3uat
  • View 3uat
Molmil generated image of 3uat
GUANYLATE KINASE DOMAINS OF THE MAGUK FAMILY SCAFFOLD PROTEINS AS SPECIFIC PHOSPHO-PROTEIN BINDING MODULES
Descriptor:Disks large homolog 1, phosphor-LGN peptide
Authors:Shang, Y., Zhu, J., Wen, W., Zhang, M.
Deposit date:2011-10-22
Release date:2011-12-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules
Embo J., 2011
5CFF
  • Download 5cff
  • View 5cff
Molmil generated image of 5cff
CRYSTAL STRUCTURE OF MIRANDA/STAUFEN DSRBD5 COMPLEX
Descriptor:Miranda, Staufen
Authors:Shan, Z., Wen, W.
Deposit date:2015-07-08
Release date:2015-10-21
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural basis of Miranda-mediated Staufen localization during Drosophila neuroblast asymmetric division
Nat Commun, 6, 2015
5XMC
  • Download 5xmc
  • View 5xmc
Molmil generated image of 5xmc
CRYSTAL STRUCTURE OF THE AUTO-INHIBITED NEDD4 FAMILY E3 LIGASE ITCH
Descriptor:E3 ubiquitin-protein ligase Itchy
Authors:Shan, Z., Wen, W.
Deposit date:2017-05-13
Release date:2017-08-02
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch
EMBO Rep., 18, 2017
5YQG
  • Download 5yqg
  • View 5yqg
Molmil generated image of 5yqg
THE STRUCTURE OF 14-3-3 AND PNUMB PEPTIDE
Descriptor:14-3-3 protein eta, Peptide from Protein numb homolog
Authors:Chen, X., Liu, Z., Wen, W.
Deposit date:2017-11-06
Release date:2018-02-07
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural determinants controlling 14-3-3 recruitment to the endocytic adaptor Numb and dissociation of the Numb/alpha-adaptin complex.
J. Biol. Chem., 293, 2018
5J19
  • Download 5j19
  • View 5j19
Molmil generated image of 5j19
PHOSPHO-PON BINDING-INDUCED PLK1 DIMERIZATION
Descriptor:Serine/threonine-protein kinase PLK1, Phosphorylated peptide from Partner of Numb, GLYCEROL
Authors:Zhu, K., Shan, Z., Zhang, L., Wen, W.
Deposit date:2016-03-29
Release date:2016-06-15
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Phospho-Pon Binding-Mediated Fine-Tuning of Plk1 Activity
Structure, 24, 2016
5YI7
  • Download 5yi7
  • View 5yi7
Molmil generated image of 5yi7
CRYSTAL STRUCTURE OF DROSOPHILA NUMB PTB DOMAIN AND PON PEPTIDE COMPLEX
Descriptor:Protein numb, Pon peptide from Partner of numb, GLYCEROL
Authors:Shan, Z., Wen, W.
Deposit date:2017-10-03
Release date:2018-04-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division.
Nat Commun, 9, 2018
<12>