2KXR

ZO1 ZU5 domain MC/AA mutation

Summary for 2KXR

• Entry DOI: 10.2210/pdb2kxr/pdb
• Related: 2KXS
• Descriptor: Tight junction protein ZO-1 (1 entity in total)
• Functional Keywords: beta-barrel, protein binding
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q07157
• Total number of polymer chains: 1
• Total formula weight: 12687.63

Authors

Wen, W.,Zhang, M. (deposition date: 2010-05-12, release date: 2011-03-30, Last modification date: 2011-07-13)

• Primary citation: Huo, L.,Wen, W.,Wang, R.,Kam, C.,Xia, J.,Feng, W.,Zhang, M.; Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration; Embo J., 30:665-678, 2011; PubMed: 21240187; DOI: 10.1038/emboj.2010.353

Experimental method

SOLUTION NMR