4Y2I | | GOLD ION BOUND TO GOLB | | Descriptor: | Putative metal-binding transport protein, GOLD ION | | Authors: | Wei, W., Wang, F., Ma, L., Zhao, J. | | Deposit date: | 2015-02-10 | | Release date: | 2016-02-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015
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4Y2K | | REDUCED FORM OF APO-GOLB | | Descriptor: | Putative metal-binding transport protein | | Authors: | Wei, W., Wang, F., Ma, L., Zhao, J. | | Deposit date: | 2015-02-10 | | Release date: | 2016-02-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015
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4Y2M | | APO-GOLB PROTEIN | | Descriptor: | Putative metal-binding transport protein, GOLD ION | | Authors: | Wei, W., Zhao, J., Wang, F. | | Deposit date: | 2015-02-10 | | Release date: | 2016-02-10 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural Insights and the Surprisingly Low Mechanical Stability of the Au-S Bond in the Gold-Specific Protein GolB
J.Am.Chem.Soc., 137, 2015
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5F0U | |
5F0W | |
5O51 | | AFROM2 CNH DOMAIN | | Descriptor: | Rho guanyl nucleotide exchange factor (Rom2), putative | | Authors: | Wei, W., van Aalten, D. | | Deposit date: | 2017-05-31 | | Release date: | 2018-06-13 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Rom2 CNH domain from Aspergillus fumigatus is an atypical seven-bladed WD-40 protein
To Be Published
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5I96 | | CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL ISOCITRATE DEHYDROGENASE (IDH2) R140Q MUTANT HOMODIMER IN COMPLEX WITH AG-221 (ENASIDENIB) INHIBITOR. | | Descriptor: | Isocitrate dehydrogenase [NADP], mitochondrial, CALCIUM ION, ... | | Authors: | Wei, W., Zhang, B., Jin, L., Jiang, F., DeLaBarre, B., Travins, J.A., Padyana, A.K. | | Deposit date: | 2016-02-19 | | Release date: | 2017-03-08 | | Last modified: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations.
Cancer Discov, 7, 2017
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4JA8 | | COMPLEX OF MITOCHONDRIAL ISOCITRATE DEHYDROGENASE R140Q MUTANT WITH AGI-6780 INHIBITOR | | Descriptor: | Isocitrate dehydrogenase [NADP], mitochondrial, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Wei, W., Chen, L., Wu, M., Jiang, F., Travins, J., Qian, K., DeLaBarre, B. | | Deposit date: | 2013-02-18 | | Release date: | 2013-04-10 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation.
Science, 340, 2013
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4MZ7 | | STRUCTURAL INSIGHT INTO DGTP-DEPENDENT ACTIVATION OF TETRAMERIC SAMHD1 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE | | Descriptor: | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Zhu, C., Gao, W., Zhao, K., Qin, X., Zhang, Y., Peng, X., Zhang, L., Dong, Y., Zhang, W., Li, P., Wei, W., Gong, Y., Yu, X.F. | | Deposit date: | 2013-09-29 | | Release date: | 2013-11-20 | | Last modified: | 2017-03-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase
Nat Commun, 4, 2013
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6L2C | | CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS MITOCHONDRIAL ACETYL-COA ACETYLTRANSFERASE IN COMPLEX WITH COA | | Descriptor: | Acetyl-CoA-acetyltransferase, putative, COENZYME A | | Authors: | Zhang, Y., Wei, W., Raimi, O.G., Ferenbach, A.T., Fang, W. | | Deposit date: | 2019-10-03 | | Release date: | 2020-02-12 | | Last modified: | 2020-04-01 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target.
Appl.Environ.Microbiol., 86, 2020
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6L2G | | CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS MITOCHONDRIAL ACETYL-COA ACETYLTRANSFERASE | | Descriptor: | Acetyl-CoA-acetyltransferase, putative | | Authors: | Zhang, Y., Wei, W., Raimi, O.G., Ferenbach, A.T., Fang, W. | | Deposit date: | 2019-10-03 | | Release date: | 2020-02-12 | | Last modified: | 2020-04-01 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target.
Appl.Environ.Microbiol., 86, 2020
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3GLR | | CRYSTAL STRUCTURE OF HUMAN SIRT3 WITH ACETYL-LYSINE ACECS2 PEPTIDE | | Descriptor: | NAD-dependent deacetylase sirtuin-3, mitochondrial, Acetyl-coenzyme A synthetase 2-like, ... | | Authors: | Jin, L., Wei, W., Jiang, Y., Peng, H., Cai, J., Mao, C., Dai, H., Bemis, J.E., Jirousek, M.R., Milne, J.C., Westphal, C.H., Perni, R.B. | | Deposit date: | 2009-03-12 | | Release date: | 2009-06-16 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes.
J.Biol.Chem., 284, 2009
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3GLS | | CRYSTAL STRUCTURE OF HUMAN SIRT3 | | Descriptor: | NAD-dependent deacetylase sirtuin-3, mitochondrial, ZINC ION, ... | | Authors: | Jin, L., Wei, W., Jiang, Y., Peng, H., Cai, J., Mao, C., Dai, H., Bemis, J.E., Jirousek, M.R., Milne, J.C., Westphal, C.H., Perni, R.B. | | Deposit date: | 2009-03-12 | | Release date: | 2009-06-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes.
J.Biol.Chem., 284, 2009
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3GLT | | CRYSTAL STRUCTURE OF HUMAN SIRT3 WITH ADPR BOUND TO THE ACECS2 PEPTIDE CONTAINING A THIOACETYL LYSINE | | Descriptor: | NAD-dependent deacetylase sirtuin-3, mitochondrial, Acetyl-coenzyme A synthetase 2-like, ... | | Authors: | Jin, L., Wei, W., Jiang, Y., Peng, H., Cai, J., Mao, C., Dai, H., Bemis, J.E., Jirousek, M.R., Milne, J.C., Westphal, C.H., Perni, R.B. | | Deposit date: | 2009-03-12 | | Release date: | 2009-06-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes.
J.Biol.Chem., 284, 2009
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3GLU | | CRYSTAL STRUCTURE OF HUMAN SIRT3 WITH ACECS2 PEPTIDE | | Descriptor: | NAD-dependent deacetylase sirtuin-3, mitochondrial, Acetyl-coenzyme A synthetase 2-like, ... | | Authors: | Jin, L., Wei, W., Jiang, Y., Peng, H., Cai, J., Mao, C., Dai, H., Bemis, J.E., Jirousek, M.R., Milne, J.C., Westphal, C.H., Perni, R.B. | | Deposit date: | 2009-03-12 | | Release date: | 2009-06-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes.
J.Biol.Chem., 284, 2009
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3UO9 | | CRYSTAL STRUCTURE OF HUMAN GAC IN COMPLEX WITH GLUTAMATE AND BPTES | | Descriptor: | Glutaminase kidney isoform, mitochondrial, GLYCEROL, ... | | Authors: | DeLaBarre, B., Gross, S., Cheng, F., Gao, Y., Jha, A., Jiang, F., Song, J.J., Wei, W., Hurov, J.B. | | Deposit date: | 2011-11-16 | | Release date: | 2011-12-07 | | Last modified: | 2013-01-02 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Full-length human glutaminase in complex with an allosteric inhibitor.
Biochemistry, 50, 2011
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4RXO | | THE STRUCTURE OF GTP-BOUND SAMHD1 | | Descriptor: | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION, PHOSPHATE ION, ... | | Authors: | Zhu, C.F., Wei, W., Peng, X., Dong, Y.H., Gong, Y., Yu, X.F. | | Deposit date: | 2014-12-11 | | Release date: | 2015-03-11 | | Last modified: | 2015-03-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTP.
Acta Crystallogr.,Sect.D, 71, 2015
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4RXP | | THE STRUCTURE OF GTP-DATP-BOUND SAMHD1 | | Descriptor: | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Zhu, C.F., Wei, W., Peng, X., Dong, Y.H., Gong, Y., Yu, X.F. | | Deposit date: | 2014-12-11 | | Release date: | 2015-03-11 | | Last modified: | 2015-03-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTP.
Acta Crystallogr.,Sect.D, 71, 2015
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4RXQ | | THE STRUCTURE OF GTP-DUTP-BOUND SAMHD1 | | Descriptor: | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, DEOXYURIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Zhu, C.F., Wei, W., Peng, X., Dong, Y.H., Gong, Y., Yu, X.F. | | Deposit date: | 2014-12-11 | | Release date: | 2015-03-11 | | Last modified: | 2015-03-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTP.
Acta Crystallogr.,Sect.D, 71, 2015
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4RXR | | THE STRUCTURE OF GTP-DCTP-BOUND SAMHD1 | | Descriptor: | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Zhu, C.F., Wei, W., Peng, X., Dong, Y.H., Gong, Y., Yu, X.F. | | Deposit date: | 2014-12-11 | | Release date: | 2015-03-11 | | Last modified: | 2015-03-25 | | Method: | X-RAY DIFFRACTION (2.117 Å) | | Cite: | The mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTP.
Acta Crystallogr.,Sect.D, 71, 2015
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4RXS | | THE STRUCTURE OF GTP-DTTP-BOUND SAMHD1 | | Descriptor: | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, THYMIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Zhu, C.F., Wei, W., Peng, X., Dong, Y.H., Gong, Y., Yu, X.F. | | Deposit date: | 2014-12-11 | | Release date: | 2015-03-11 | | Last modified: | 2015-03-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTP.
Acta Crystallogr.,Sect.D, 71, 2015
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5XS9 | |
6K1T | |
5I95 | | CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL ISOCITRATE DEHYDROGENASE R140Q MUTANT HOMODIMER BOUND TO NADPH AND ALPHA-KETOGLUTARIC ACID | | Descriptor: | Isocitrate dehydrogenase [NADP], mitochondrial, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Zhang, B., Jin, L., Wu, W., Jiang, F., DeLaBarre, B., Travins, J.A., Padyana, A.K. | | Deposit date: | 2016-02-19 | | Release date: | 2017-03-01 | | Last modified: | 2017-07-05 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations.
Cancer Discov, 7, 2017
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2HMG | | REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING | | Descriptor: | HEMAGGLUTININ (HA1 CHAIN), HEMAGGLUTININ (HA2 CHAIN), beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Weis, W.I., Bruenger, A.T., Skehel, J.J., Wiley, D.C. | | Deposit date: | 1989-09-11 | | Release date: | 1991-01-15 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Refinement of the influenza virus hemagglutinin by simulated annealing.
J.Mol.Biol., 212, 1990
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