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6G16
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STRUCTURE OF THE HUMAN RBBP4:MTA1(464-546) COMPLEX SHOWING LOOP EXCHANGE
Descriptor:Histone-binding protein RBBP4, Metastasis-associated protein MTA1
Authors:Millard, C.J., Varma, N., Fairall, L., Schwabe, J.W.R.
Deposit date:2018-03-20
Release date:2018-06-13
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the human RBBP4:MTA1(464-546) complex showing loop exchange
To be published
5ICN
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HDAC1:MTA1 IN COMPLEX WITH INOSITOL-6-PHOSPHATE AND A NOVEL PEPTIDE INHIBITOR BASED ON HISTONE H4
Descriptor:Metastasis-associated protein MTA1, Histone deacetylase 1, GLY-ALA-6A0-ARG-HIS, ...
Authors:Millard, C.J., Robertson, N.S., Watson, P.J., Jameson, A.G., Schwabe, J.W.R.
Deposit date:2016-02-23
Release date:2016-05-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.
Nat Commun, 7, 2016
5FXY
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STRUCTURE OF THE HUMAN RBBP4:MTA1(464-546) COMPLEX
Descriptor:HISTONE-BINDING PROTEIN RBBP4, METASTASIS-ASSOCIATED PROTEIN MTA1
Authors:Millard, C.J., Varma, N., Fairall, L., Schwabe, J.W.R.
Deposit date:2016-03-03
Release date:2016-05-18
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of the core NuRD repression complex provides insights into its interaction with chromatin.
Elife, 5, 2016
4D6K
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STRUCTURE OF DNTTIP1 DIMERISATION DOMAIN.
Descriptor:DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1
Authors:Itoh, T., Fairall, L., Schwabe, J.W.R.
Deposit date:2014-11-11
Release date:2015-02-18
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Characterization of a Cell Cycle Associated Hdac1/2 Complex Reveals the Structural Basis for Complex Assembly and Nucleosome Targeting.
Nucleic Acids Res., 43, 2015
4BKX
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THE STRUCTURE OF HDAC1 IN COMPLEX WITH THE DIMERIC ELM2-SANT DOMAIN OF MTA1 FROM THE NURD COMPLEX
Descriptor:METASTASIS-ASSOCIATED PROTEIN MTA1, HISTONE DEACETYLASE 1, ZINC ION, ...
Authors:Millard, C.J., Watson, P.J., Celardo, I., Gordiyenko, Y., Cowley, S.M., Robinson, C.V., Fairall, L., Schwabe, J.W.R.
Deposit date:2013-04-30
Release date:2013-07-03
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Class I Hdacs Share a Common Mechanism of Regulation by Inositol Phosphates.
Mol.Cell, 51, 2013
4A69
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STRUCTURE OF HDAC3 BOUND TO COREPRESSOR AND INOSITOL TETRAPHOSPHATE
Descriptor:HISTONE DEACETYLASE 3,, NUCLEAR RECEPTOR COREPRESSOR 2, ZINC ION, ...
Authors:Watson, P.J., Fairall, L., Santos, G.M., Schwabe, J.W.R.
Deposit date:2011-11-01
Release date:2012-01-11
Last modified:2012-01-25
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure of Hdac3 Bound to Co-Repressor and Inositol Tetraphosphate.
Nature, 481, 2012
3U66
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CRYSTAL STRUCTURE OF T6SS SCIP/TSSL FROM ESCHERICHIA COLI ENTEROAGGREGATIVE 042
Descriptor:Putative type VI secretion protein, GLYCEROL
Authors:Durand, E., Aschtgen, M.S., Zoued, A., Spinelli, S., Watson, P.J.H., Cambillau, C., Cascales, E.
Deposit date:2011-10-12
Release date:2012-03-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Structural characterization and oligomerization of the TssL protein, a component shared by bacterial type VI and type IVb secretion systems.
J.Biol.Chem., 287, 2012
2XTE
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STRUCTURE OF THE TBL1 TETRAMERISATION DOMAIN
Descriptor:F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J., Fairall, L., Watson, P.J., Greenwood, J.A., Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTD
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STRUCTURE OF THE TBL1 TETRAMERISATION DOMAIN
Descriptor:TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J., Fairall, L., Watson, P.J., Greenwood, J.A., Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2XTC
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STRUCTURE OF THE TBL1 TETRAMERISATION DOMAIN
Descriptor:F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X
Authors:Oberoi, J., Fairall, L., Watson, P.J., Greenwood, J.A., Schwabe, J.W.R.
Deposit date:2010-10-06
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery.
Nat.Struct.Mol.Biol., 18, 2011
2MWI
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THE STRUCTURE OF THE CARBOXY-TERMINAL DOMAIN OF DNTTIP1
Descriptor:Deoxynucleotidyltransferase terminal-interacting protein 1
Authors:Schwabe, J.W.R., Muskett, F.W., Itoh, T.
Deposit date:2014-11-11
Release date:2015-02-18
Last modified:2015-03-18
Method:SOLUTION NMR
Cite:Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.
Nucleic Acids Res., 43, 2015
2L5G
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CO-ORDINATES AND 1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR THE COMPLEX OF GPS2 53-90 AND SMRT 167-207
Descriptor:G protein pathway suppressor 2, Putative uncharacterized protein NCOR2
Authors:Oberoi, J., Yang, J., Neuhaus, D., Schwabe, J.W.R.
Deposit date:2010-11-01
Release date:2011-02-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery.
Nat.Struct.Mol.Biol., 18, 2011
1Z2X
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CRYSTAL STRUCTURE OF MOUSE VPS29
Descriptor:Vacuolar protein sorting 29
Authors:Collins, B.M., Skinner, C.F., Watson, P.J., Seaman, M.N.J., Owen, D.J.
Deposit date:2005-03-10
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly
NAT.STRUCT.MOL.BIOL., 12, 2005
1Z2W
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CRYSTAL STRUCTURE OF MOUSE VPS29 COMPLEXED WITH MN2+
Descriptor:Vacuolar protein sorting 29, MANGANESE (II) ION, GLYCEROL
Authors:Collins, B.M., Skinner, C.F., Watson, P.J., Seaman, M.N.J., Owen, D.J.
Deposit date:2005-03-10
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly
NAT.STRUCT.MOL.BIOL., 12, 2005
1UTC
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CLATHRIN TERMINAL DOMAIN COMPLEXED WITH TLPWDLWTT
Descriptor:CLATHRIN HEAVY CHAIN, AMPHIPHYSIN
Authors:Miele, A.E., Evans, P.R., Owen, D.J.
Deposit date:2003-12-08
Release date:2004-02-25
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain beta-propeller.
Nat. Struct. Mol. Biol., 11, 2004
1R4X
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CRYSTAL STRUCTURE ANALYS OF THE GAMMA-COPI APPENDAGE DOMAIN
Descriptor:Coatomer gamma subunit, MAGNESIUM ION
Authors:Watson, P.J., Frigerio, G., Collins, B.M., Duden, R., Owen, D.J.
Deposit date:2003-10-09
Release date:2003-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Gamma-COP appendage domain - structure and function
Traffic, 5, 2004
1NAF
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CRYSTAL STRUCTURE OF THE HUMAN GGA1 GAT DOMAIN
Descriptor:ADP-ribosylation factor binding protein GGA1
Authors:Collins, B.M., Watson, P.J., Owen, D.J.
Deposit date:2002-11-27
Release date:2003-03-25
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the GGA1-GAT Domain Reveals the Molecular Basis for ARF Binding and Membrane Association of GGAs
Dev.Cell, 4, 2003