Author results

5J5C
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CRYSTAL STRUCTURE OF ARL1-GTP AND DCB DOMAIN OF BIG1 COMPLEX
Descriptor:ADP-ribosylation factor-like protein 1, Brefeldin A-inhibited guanine nucleotide-exchange protein 1, MAGNESIUM ION, ...
Authors:Wang, R., Wang, Z., Zhang, T., Ding, J.
Deposit date:2016-04-02
Release date:2016-09-28
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for targeting BIG1 to Golgi apparatus through interaction of its DCB domain with Arl1
J Mol Cell Biol, 2016
2LRW
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SOLUTION STRUCTURE OF A UBIQUITIN-LIKE PROTEIN FROM TRYPANOSOMA BRUCEI
Descriptor:Ubiquitin, putative
Authors:Wang, R., Wang, T., Liao, S., Zhang, J., Tu, X.
Deposit date:2012-04-13
Release date:2013-04-24
Method:SOLUTION NMR
Cite:Solution structure of a ubiqutin-like protein from Trypanosoma bucei
To be Published
5JHG
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE HUMAN RHOA AND THE DH/PH DOMAIN OF HUMAN ARHGEF11
Descriptor:Rho guanine nucleotide exchange factor 11, Transforming protein RhoA, GLYCEROL
Authors:Wang, R., Chen, Q., Zhang, H., Yan, Z., Li, J., Miao, L., Wang, F.
Deposit date:2016-04-21
Release date:2017-04-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11
To Be Published
2M1H
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SOLUTION STRUCTURE OF A PWWP DOMAIN FROM TRYPANOSOMA BRUCEI
Descriptor:Transcription elongation factor S-II
Authors:Wang, R., Fan, K., Liao, S., Zhang, J., Tu, X.
Deposit date:2012-11-28
Release date:2013-12-04
Last modified:2016-06-22
Method:SOLUTION NMR
Cite:Solution structure of TbTFIIS2-1 PWWP domain from Trypanosoma brucei.
Proteins, 84, 2016
2NAS
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SOLUTION STRUCTURE OF A PWWP DOAMIN FROM TRYPANOSOMA BRUCEI
Descriptor:Uncharacterized protein
Authors:Wang, R., Liao, S., Dai, K., Zhang, J., Tu, X.
Deposit date:2016-01-10
Release date:2017-01-18
Method:SOLUTION NMR
Cite:Soluion Structure of a PWWP domain from Trypanosoma brucei
To be Published
3DMM
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CRYSTAL STRUCTURE OF THE CD8 ALPHA BETA/H-2DD COMPLEX
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2 microglobulin, ...
Authors:Wang, R., Natarajan, K., Margulies, D.H.
Deposit date:2008-07-01
Release date:2009-07-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position.
J.Immunol., 183, 2009
3G5B
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THE STRUCTURE OF UNC5B CYTOPLASMIC DOMAIN
Descriptor:Netrin receptor UNC5B, PHOSPHATE ION
Authors:Wang, R., Wei, Z., Zhang, M.
Deposit date:2009-02-04
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor
Mol.Cell, 33, 2009
3GS2
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RING1B C-TERMINAL DOMAIN/CBX7 CBOX COMPLEX
Descriptor:E3 ubiquitin-protein ligase RING2, Chromobox protein homolog 7, SULFATE ION, ...
Authors:Wang, R., Taylor, A.B., Kim, C.A.
Deposit date:2009-03-26
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain.
Structure, 18, 2010
3IXS
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RING1B C-TERMINAL DOMAIN/RYBP C-TERMINAL DOMAIN COMPLEX
Descriptor:E3 ubiquitin-protein ligase RING2, RING1 and YY1-binding protein, 1,2-ETHANEDIOL, ...
Authors:Wang, R., Taylor, A.B., Kim, C.A.
Deposit date:2009-09-04
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain.
Structure, 18, 2010
3PKM
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CRYSTAL STRUCTURE OF CAS6 WITH ITS SUBSTRATE RNA
Descriptor:Cas6 protein, 5'-R(*AP*UP*UP*AP*CP*AP*AP*UP*AP*A)-3', 5'-R(P*UP*UP*AP*CP*AP*AP*UP*AP*A)-3'
Authors:Wang, R., Preamplume, G., Li, H.
Deposit date:2010-11-11
Release date:2011-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.103 Å)
Cite:Interaction of the Cas6 Riboendonuclease with CRISPR RNAs: Recognition and Cleavage.
Structure, 19, 2011
3QJJ
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ONE RAMP PROTEIN BINDING DIFFERENT RNA SUBSTRATES
Descriptor:RNA (5'-R(*GP*UP*UP*GP*AP*AP*AP*UP*CP*AP*GP*A)-3'), Putative uncharacterized protein PH0350
Authors:Wang, R., Zheng, H., Preamplume, G., Li, H.
Deposit date:2011-01-29
Release date:2012-02-08
Method:X-RAY DIFFRACTION (2.8049 Å)
Cite:Cooperative and Specific Binding of a RAMP Protein to Single-stranded CRISPR Repeat RNA
To be Published
3QJL
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ONE RAMP PROTEIN BINDING DIFFERENT RNA SUBSTRATES
Descriptor:Putative uncharacterized protein PH0350, RNA (5'-R(*GP*UP*UP*AP*CP*AP*AP*UP*AP*AP*GP*A)-3')
Authors:Wang, R., Zheng, H., Preamplume, G., Li, H.
Deposit date:2011-01-30
Release date:2012-02-08
Method:X-RAY DIFFRACTION (2.7009 Å)
Cite:Cooperative and Specific Binding of a RAMP Protein to Single-stranded CRISPR Repeat RNA
To be Published
3QJP
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AN RAMP PROTEIN BINDING DIFFERENT RNA SUBSTRATES
Descriptor:RNA (5'-R(P*UP*AP*GP*UP*UP*UP*AP*A)-3'), Putative uncharacterized protein PH0350
Authors:Wang, R., Zheng, H., Preamplume, G., Li, H.
Deposit date:2011-01-30
Release date:2012-02-08
Method:X-RAY DIFFRACTION (3.2986 Å)
Cite:Cooperative and Specific Binding of a RAMP Protein to Single-stranded CRISPR Repeat RNA
To be Published
4G59
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CRYSTAL STRUCTURE OF THE MURINE CYTOMEGALOVIRUS MHC-I HOMOLOG M152 WITH LIGAND RAE-1 GAMMA
Descriptor:Retinoic acid early-inducible protein 1-gamma, M152 protein, N-ACETYL-D-GLUCOSAMINE
Authors:Wang, R., Natarajan, K., Margulies, D.H.
Deposit date:2012-07-17
Release date:2012-12-19
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1gamma reveals a paradigm for MHC/MHC interaction in immune evasion.
Proc.Natl.Acad.Sci.USA, 109, 2012
4PUT
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CRYSTAL STRUCTURE OF THE ARABIDOPSIS THALIANA TOP2 OLIGOPEPTIDASE
Descriptor:Cytosolic oligopeptidase A, ZINC ION, CHLORIDE ION
Authors:Wang, R., Rajagopalan, K., Tong, L.
Deposit date:2014-03-13
Release date:2014-05-14
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Arabidopsis thaliana TOP2 oligopeptidase.
Acta Crystallogr F Struct Biol Commun, 70, 2014
5GO0
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SOLUTION STRUCTURE OF NEDD8 FROM TRYPANOSOMA BRUCEI
Descriptor:Ubiquitin, putative
Authors:Wang, R., Liao, S., Zhang, J., Tu, X.
Deposit date:2016-07-25
Release date:2017-07-26
Method:SOLUTION NMR
Cite:Solution structure of nedd8 from Trypanosoma brucei
To Be Published
4WVD
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IDENTIFICATION OF A NOVEL FXR LIGAND THAT REGULATES METABOLISM
Descriptor:Nuclear receptor corepressor 1, Bile acid receptor, FORMIC ACID, ...
Authors:Wang, R., Li, Y.
Deposit date:2014-11-05
Release date:2015-02-11
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The antiparasitic drug ivermectin is a novel FXR ligand that regulates metabolism.
Nat Commun, 4, 2013
5GT9
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THE X-RAY STRUCTURE OF 7BETA-HYDROXYSTEROID DEHYDROGENASE
Descriptor:Oxidoreductase, short chain dehydrogenase/reductase family protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wang, F., Wang, R., Lv, Z., Chen, Q., Huo, X.
Deposit date:2016-08-19
Release date:2017-05-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of NADP(+)-bound 7 beta-hydroxysteroid dehydrogenase reveals two cofactor-binding modes
Acta Crystallogr F Struct Biol Commun, 73, 2017
5JHH
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CRYSTAL STRUCTURE OF THE TERNARY COMPLEX BETWEEN THE HUMAN RHOA, ITS INHIBITOR AND THE DH/PH DOMAIN OF HUMAN ARHGEF11
Descriptor:Rho guanine nucleotide exchange factor 11, Transforming protein RhoA, GLYCEROL, ...
Authors:Lv, Z., Wang, R., Ma, L., Miao, Q., Wu, J., Yan, Z., Li, J., Miao, L., Wang, F.
Deposit date:2016-04-21
Release date:2017-04-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and PDZRhoGEF
To Be Published
2NSF
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CRYSTAL STRUCTURE OF THE MYCOTHIOL-DEPENDENT MALEYLPYRUVATE ISOMERASE
Descriptor:Hypothetical protein Cgl3021, SULFATE ION, ZINC ION, ...
Authors:Chang, W.R., Wang, R.
Deposit date:2006-11-04
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structures and Site-directed Mutagenesis of a Mycothiol-dependent Enzyme Reveal a Novel Folding and Molecular Basis for Mycothiol-mediated Maleylpyruvate Isomerization
J.Biol.Chem., 282, 2007
2NSG
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CRYSTAL STRUCTURE OF THE MYCOTHIOL-DEPENDENT MALEYLPYRUVATE ISOMERASE H52A MUTANT
Descriptor:Hypothetical protein Cgl3021, SULFATE ION, GLYCEROL
Authors:Chang, W.R., Wang, R.
Deposit date:2006-11-04
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structures and Site-directed Mutagenesis of a Mycothiol-dependent Enzyme Reveal a Novel Folding and Molecular Basis for Mycothiol-mediated Maleylpyruvate Isomerization
J.Biol.Chem., 282, 2007
5KKN
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CRYSTAL STRUCTURE OF HUMAN ACC2 BC DOMAIN IN COMPLEX WITH ND-646, THE PRIMARY AMIDE OF ND-630
Descriptor:Acetyl-CoA carboxylase 2, 2-[1-[(2~{R})-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-bis(oxidanylidene)thieno[2,3-d]pyrimidin-3-yl]-2-methyl-propanamide
Authors:Wang, R., Paul, D., Tong, L.
Deposit date:2016-06-22
Release date:2016-07-13
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.
Proc.Natl.Acad.Sci.USA, 113, 2016
3E6F
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MHC CLASS I H-2DD HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND A VARIANT PEPTIDE, PA9, FROM THE HUMAN IMMUNODEFICIENCY VIRUS (BAL) ENVELOPE GLYCOPROTEIN 120
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, BETA-2 MICROGLOBULIN, ...
Authors:Wang, R., Natarajan, K., Robinson, H., Margulies, D.H.
Deposit date:2008-08-15
Release date:2009-08-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity
J.Immunol., 183, 2009
3E6H
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MHC CLASS I H-2DD HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND A VARIANT PEPTIDE, PI10, FROM THE HUMAN IMMUNODEFICIENCY VIRUS (BAL) ENVELOPE GLYCOPROTEIN 120
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Putative uncharacterized protein, ...
Authors:Wang, R., Natarajan, K., Robinson, H., Margulies, D.H.
Deposit date:2008-08-15
Release date:2009-08-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity
J.Immunol., 183, 2009
3ECB
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CRYSTAL STRUCTURE OF MOUSE H-2DD IN COMPLEX WITH PEPTIDE P18-I10 DERIVED FROM HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2 microglobulin, ...
Authors:Natarajan, K., Wang, R., Margulies, D.H.
Deposit date:2008-08-29
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position
J.Immunol., 183, 2009