7KHR

Cryo-EM structure of bafilomycin A1-bound intact V-ATPase from bovine brain

Summary for 7KHR

• Entry DOI: 10.2210/pdb7khr/pdb
• EMDB information: 22880
• Descriptor: V-type proton ATPase catalytic subunit A, V-type proton ATPase 21 kDa proteolipid subunit, V-type proton ATPase subunit d 1, ... (25 entities in total)
• Functional Keywords: proton transport, bafilomycin a1
• Biological source: Bos taurus (Bovine); More
• Total number of polymer chains: 32
• Total formula weight: 1060373.81

Authors

Wang, R.,Li, X. (deposition date: 2020-10-21, release date: 2021-03-17, Last modification date: 2021-09-29)

• Primary citation: Wang, R.,Wang, J.,Hassan, A.,Lee, C.H.,Xie, X.S.,Li, X.; Molecular basis of V-ATPase inhibition by bafilomycin A1.; Nat Commun, 12:1782-1782, 2021; PubMed: 33741963; DOI: 10.1038/s41467-021-22111-5

Experimental method

ELECTRON MICROSCOPY (3.62 Å)