3PKM

Crystal structure of Cas6 with its substrate RNA

Summary for 3PKM

• Entry DOI: 10.2210/pdb3pkm/pdb
• Descriptor: CRISPR-associated endoribonuclease Cas6, 5'-R(*AP*UP*UP*AP*CP*AP*AP*UP*AP*A)-3', 5'-R(P*UP*UP*AP*CP*AP*AP*UP*AP*A)-3' (3 entities in total)
• Functional Keywords: cas6, crispr, endonuclease, ferridoxin fold, crispr processing endonuclease, repeat rna, hydrolase-rna complex, hydrolase/rna
• Biological source: Pyrococcus furiosus; More
• Total number of polymer chains: 4
• Total formula weight: 68608.98

Authors

Wang, R.,Preamplume, G.,Li, H. (deposition date: 2010-11-11, release date: 2011-03-09, Last modification date: 2024-02-21)

• Primary citation: Wang, R.,Preamplume, G.,Terns, M.P.,Terns, R.M.,Li, H.; Interaction of the Cas6 Riboendonuclease with CRISPR RNAs: Recognition and Cleavage.; Structure, 19:257-264, 2011; PubMed: 21300293; DOI: 10.1016/j.str.2010.11.014

Experimental method

X-RAY DIFFRACTION (3.103 Å)