3PKM

Crystal structure of Cas6 with its substrate RNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004519	molecular_function	endonuclease activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0043571	biological_process	maintenance of CRISPR repeat elements
A	0051607	biological_process	defense response to virus
X	0003723	molecular_function	RNA binding
X	0004519	molecular_function	endonuclease activity
X	0016788	molecular_function	hydrolase activity, acting on ester bonds
X	0043571	biological_process	maintenance of CRISPR repeat elements
X	0051607	biological_process	defense response to virus

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:20884784

Chain	Residue	Details
A	TYR37
X	TYR37

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:20884784

Chain	Residue	Details
A	HIS52
X	HIS52

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site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Transition state stabilizer => ECO:0000305|PubMed:20884784

Chain	Residue	Details
A	LYS58
X	LYS58

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