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4UXT
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BU of 4uxt by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN HEAVY CHAIN ISOFORM 5A, ...
Authors:Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
Deposit date:2014-08-27
Release date:2014-09-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UXS
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BU of 4uxs by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ...
Authors:Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
Deposit date:2014-08-27
Release date:2014-09-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UXR
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BU of 4uxr by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
Deposit date:2014-08-27
Release date:2014-09-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UY0
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BU of 4uy0 by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
Deposit date:2014-08-27
Release date:2014-09-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UXO
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BU of 4uxo by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ...
Authors:Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
Deposit date:2014-08-27
Release date:2014-09-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UXP
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BU of 4uxp by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ...
Authors:Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
Deposit date:2014-08-27
Release date:2014-09-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UXY
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BU of 4uxy by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Descriptor: ALPHA TUBULIN, BETA TUBULIN, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
Deposit date:2014-08-27
Release date:2014-09-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
6ZPH
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BU of 6zph by Molmil
Kinesin binding protein complexed with Kif15 motor domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, KIF-binding protein, Kinesin-like protein KIF15, ...
Authors:Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A.
Deposit date:2020-07-08
Release date:2020-12-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:The mechanism of kinesin inhibition by kinesin-binding protein.
Elife, 9, 2020
6ZPI
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BU of 6zpi by Molmil
Microtubule complexed with Kif15 motor domain. Symmetrised asymmetric unit
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF15, ...
Authors:Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A.
Deposit date:2020-07-08
Release date:2020-12-30
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:The mechanism of kinesin inhibition by kinesin-binding protein.
Elife, 9, 2020
6ZPG
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BU of 6zpg by Molmil
Kinesin binding protein (KBP)
Descriptor: KIF-binding protein
Authors:Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A.
Deposit date:2020-07-08
Release date:2020-12-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:The mechanism of kinesin inhibition by kinesin-binding protein.
Elife, 9, 2020
3M4I
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BU of 3m4i by Molmil
Crystal structure of the second part of the Mycobacterium tuberculosis DNA gyrase reaction core: the TOPRIM domain at 1.95 A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA gyrase subunit B
Authors:Piton, J, Petrella, S, Aubry, A, Mayer, C.
Deposit date:2010-03-11
Release date:2010-09-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase.
Plos One, 5, 2010
6XZC
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BU of 6xzc by Molmil
CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis
Descriptor: ESX-1 secretion-associated protein EspB
Authors:Piton, J, Pojer, F, Wakatsuki, S, Gati, C, Cole, S.T.
Deposit date:2020-02-03
Release date:2020-06-17
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:High resolution CryoEM structure of the ring-shaped virulence factor EspB fromMycobacterium tuberculosis.
J Struct Biol X, 4, 2020
4IC4
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BU of 4ic4 by Molmil
Crystal structure of Osh3 ORD from Saccharomyces cerevisiae
Descriptor: Oxysterol-binding protein homolog 3
Authors:Tong, J, Im, Y.J.
Deposit date:2012-12-09
Release date:2013-07-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins
Structure, 21, 2013
4IAP
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BU of 4iap by Molmil
Crystal structure of PH domain of Osh3 from Saccharomyces cerevisiae
Descriptor: Oxysterol-binding protein homolog 3,Endolysin,Oxysterol-binding protein homolog 3, SULFATE ION
Authors:Tong, J, Im, Y.J.
Deposit date:2012-12-07
Release date:2013-07-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins
Structure, 21, 2013
4INQ
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BU of 4inq by Molmil
Crystal structure of Osh3 ORD in complex with PI(4)P from Saccharomyces cerevisiae
Descriptor: (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Oxysterol-binding protein homolog 3
Authors:Tong, J, Im, Y.J.
Deposit date:2013-01-05
Release date:2013-07-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins
Structure, 21, 2013
5ND7
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BU of 5nd7 by Molmil
Microtubule-bound MKLP2 motor domain in the presence of AMPPNP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF20A, ...
Authors:Atherton, J, Yu, I.-M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A.
Deposit date:2017-03-07
Release date:2017-10-04
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Elife, 6, 2017
5ND4
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BU of 5nd4 by Molmil
Microtubule-bound MKLP2 motor domain in the presence of ADP.AlFx
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Atherton, J, Yu, I.-M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A.
Deposit date:2017-03-07
Release date:2017-10-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Elife, 6, 2017
5ND2
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BU of 5nd2 by Molmil
Microtubule-bound MKLP2 motor domain in the presence of ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Atherton, J, Yu, I.M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A.
Deposit date:2017-03-07
Release date:2017-10-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Elife, 6, 2017
5ND3
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BU of 5nd3 by Molmil
Microtubule-bound MKLP2 motor domain in the with no nucleotide
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF20A, ...
Authors:Atherton, J, Yu, I.M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A.
Deposit date:2017-03-07
Release date:2017-10-04
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Elife, 6, 2017
1YAT
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BU of 1yat by Molmil
IMPROVED CALCINEURIN INHIBITION BY YEAST FKBP12-DRUG COMPLEXES. CRYSTALLOGRAPHIC AND FUNCTIONAL ANALYSIS
Descriptor: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506 BINDING PROTEIN
Authors:Rotonda, J, Becker, J.W.
Deposit date:1993-01-06
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Improved calcineurin inhibition by yeast FKBP12-drug complexes. Crystallographic and functional analysis.
J.Biol.Chem., 268, 1993
8QKK
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BU of 8qkk by Molmil
Cryo-EM structure of MmpL3 from Mycobacterium smegmatis reconstituted into peptidiscs
Descriptor: Trehalose monomycolate exporter MmpL3
Authors:Couston, J, Guo, Z, Wang, K, Gourdon, P.E, Blaise, M.
Deposit date:2023-09-15
Release date:2023-11-15
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Cryo-EM structure of the trehalose monomycolate transporter, MmpL3, reconstituted into peptidiscs.
Curr Res Struct Biol, 6, 2023
6IYB
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BU of 6iyb by Molmil
Structure of human ORP1 ANK - Rab7 complex
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Oxysterol-binding protein-related protein 1, ...
Authors:Tong, J, Im, Y.J.
Deposit date:2018-12-14
Release date:2019-03-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:Structural basis of human ORP1-Rab7 interaction for the late-endosome and lysosome targeting.
PLoS ONE, 14, 2019
6G83
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BU of 6g83 by Molmil
Crystal structure of M. tuberculosis DprE1 in complex with sPBTZ169 (sulfonylPBTZ)
Descriptor: Decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, [2-(4-cyclohexylsulfonylpiperazin-1-yl)-4-oxidanylidene-6-(trifluoromethyl)-1,3-benzothiazin-8-yl]-oxidanylidene-azanium
Authors:Piton, J, Makarov, V, Cole, S.T.
Deposit date:2018-04-07
Release date:2018-08-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis.
Antimicrob. Agents Chemother., 62, 2018
5MKD
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BU of 5mkd by Molmil
Crystal structure of Bacillus subtilis Ywea
Descriptor: Ywea
Authors:Carrington, J, van Aalten, D.
Deposit date:2016-12-03
Release date:2017-01-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal structure of Bacillus subtilis Ywea
To Be Published
4JZT
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BU of 4jzt by Molmil
Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH (E68A mutant) bound to GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, dGTP pyrophosphohydrolase
Authors:Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C.
Deposit date:2013-04-03
Release date:2013-05-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013

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