1YAT

IMPROVED CALCINEURIN INHIBITION BY YEAST FKBP12-DRUG COMPLEXES. CRYSTALLOGRAPHIC AND FUNCTIONAL ANALYSIS

Summary for 1YAT

Entry DOI	10.2210/pdb1yat/pdb
Descriptor	FK506 BINDING PROTEIN, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN (3 entities in total)
Functional Keywords	binding protein
Biological source	Saccharomyces cerevisiae (baker's yeast)
Cellular location	Cytoplasm: P20081
Total number of polymer chains	1
Total formula weight	12842.65
Authors	Rotonda, J.,Becker, J.W. (deposition date: 1993-01-06, release date: 1993-10-31, Last modification date: 2024-02-14)
Primary citation	Rotonda, J.,Burbaum, J.J.,Chan, H.K.,Marcy, A.I.,Becker, J.W. Improved calcineurin inhibition by yeast FKBP12-drug complexes. Crystallographic and functional analysis. J.Biol.Chem., 268:7607-7609, 1993 Cited by PubMed: 7681823 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation