3M4I
Crystal structure of the second part of the Mycobacterium tuberculosis DNA gyrase reaction core: the TOPRIM domain at 1.95 A resolution
Summary for 3M4I
Entry DOI | 10.2210/pdb3m4i/pdb |
Related | 2ZJT 3IFZ 3IG0 |
Descriptor | DNA gyrase subunit B, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total) |
Functional Keywords | dna gyrase, gyrb, toprim, type ii topoisomerase, tuberculosis, quinolone binding site, dna binding site, atp-binding, isomerase, nucleotide-binding, topoisomerase |
Biological source | Mycobacterium tuberculosis |
Cellular location | Cytoplasm (Potential): P0C5C5 |
Total number of polymer chains | 1 |
Total formula weight | 27537.43 |
Authors | Piton, J.,Petrella, S.,Aubry, A.,Mayer, C. (deposition date: 2010-03-11, release date: 2010-09-29, Last modification date: 2023-11-01) |
Primary citation | Piton, J.,Petrella, S.,Delarue, M.,Andre-Leroux, G.,Jarlier, V.,Aubry, A.,Mayer, C. Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase. Plos One, 5:e12245-e12245, 2010 Cited by PubMed: 20805881DOI: 10.1371/journal.pone.0012245 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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