3M4I

Crystal structure of the second part of the Mycobacterium tuberculosis DNA gyrase reaction core: the TOPRIM domain at 1.95 A resolution

Summary for 3M4I

Entry DOI	10.2210/pdb3m4i/pdb
Related	2ZJT 3IFZ 3IG0
Descriptor	DNA gyrase subunit B, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
Functional Keywords	dna gyrase, gyrb, toprim, type ii topoisomerase, tuberculosis, quinolone binding site, dna binding site, atp-binding, isomerase, nucleotide-binding, topoisomerase
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (Potential): P0C5C5
Total number of polymer chains	1
Total formula weight	27537.43
Authors	Piton, J.,Petrella, S.,Aubry, A.,Mayer, C. (deposition date: 2010-03-11, release date: 2010-09-29, Last modification date: 2023-11-01)
Primary citation	Piton, J.,Petrella, S.,Delarue, M.,Andre-Leroux, G.,Jarlier, V.,Aubry, A.,Mayer, C. Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase. Plos One, 5:e12245-e12245, 2010 Cited by PubMed: 20805881 DOI: 10.1371/journal.pone.0012245 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation