Author results

1A3C
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PYRR, THE BACILLUS SUBTILIS PYRIMIDINE BIOSYNTHETIC OPERON REPRESSOR, DIMERIC FORM
Descriptor:PYRIMIDINE OPERON REGULATORY PROTEIN PYRR, SAMARIUM (III) ION, SULFATE ION
Authors:Tomchick, D.R., Turner, R.J., Switzer, R.W., Smith, J.L.
Deposit date:1998-01-20
Release date:1998-08-05
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Adaptation of an enzyme to regulatory function: structure of Bacillus subtilis PyrR, a pyr RNA-binding attenuation protein and uracil phosphoribosyltransferase.
Structure, 6, 1998
1A4X
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PYRR, THE BACILLUS SUBTILIS PYRIMIDINE BIOSYNTHETIC OPERON REPRESSOR, HEXAMERIC FORM
Descriptor:PYRIMIDINE OPERON REGULATORY PROTEIN PYRR, SULFATE ION
Authors:Tomchick, D.R., Turner, R.J., Switzer, R.W., Smith, J.L.
Deposit date:1998-02-08
Release date:1998-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Adaptation of an enzyme to regulatory function: structure of Bacillus subtilis PyrR, a pyr RNA-binding attenuation protein and uracil phosphoribosyltransferase.
Structure, 6, 1998
1F8N
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, NEW REFINEMENT
Descriptor:LIPOXYGENASE-1, FE (II) ION
Authors:Tomchick, D.R., Minor, W., Holman, T.
Deposit date:2000-06-30
Release date:2001-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGM
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, N694H MUTANT
Descriptor:SEED LIPOXYGENASE-1, FE (III) ION
Authors:Tomchick, D.R., Minor, W., Holman, T.R.
Deposit date:2000-07-28
Release date:2001-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGO
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q495A MUTANT
Descriptor:SEED LIPOXYGENASE-1, FE (III) ION
Authors:Tomchick, D.R., Minor, W., Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGQ
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q495E MUTANT
Descriptor:SEED LIPOXYGENASE-1, FE (III) ION
Authors:Tomchick, D.R., Minor, W., Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGR
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q697E MUTANT
Descriptor:SEED LIPOXYGENASE-1, FE (III) ION
Authors:Tomchick, D.R., Minor, W., Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
1FGT
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LIPOXYGENASE-1 (SOYBEAN) AT 100K, Q697N MUTANT
Descriptor:SEED LIPOXYGENASE-1, FE (III) ION
Authors:Tomchick, D.R., Minor, W., Holman, T.
Deposit date:2000-07-28
Release date:2001-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.
Biochemistry, 40, 2001
3BEN
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STRUCTURE OF N-(12-IMIDAZOLYL-DODECANOYL)-L-LEUCINE INHIBITOR BOUND TO THE HEME DOMAIN OF CYTOCHROME P450-BM3
Descriptor:Cytochrome P450 102, PROTOPORPHYRIN IX CONTAINING FE, N-[12-(1H-imidazol-1-yl)dodecanoyl]-L-leucine, ...
Authors:Tomchick, D.R.
Deposit date:2007-11-19
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.
Biochemistry, 47, 2008
4M63
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CRYSTAL STRUCTURE OF A FILAMENT-LIKE ACTIN TRIMER BOUND TO THE BACTERIAL EFFECTOR VOPL
Descriptor:T3SS2 effector VopL nucleation of actin polymerization, Actin-5C, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Tomchick, D.R., Zahm, J.A., Rosen, M.K.
Deposit date:2013-08-08
Release date:2013-10-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.748 Å)
Cite:The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
Cell(Cambridge,Mass.), 155, 2013
5EW4
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CRYSTAL STRUCTURE OF C9ORF72 ANTISENSE CCCCGG REPEAT RNA ASSOCIATED WITH LOU GEHRIG'S DISEASE AND FRONTOTEMPORAL DEMENTIA, CRYSTALLIZED WITH SR2+
Descriptor:RNA (5'-R(*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*GP*GP*CP*CP*CP*C)-3'), POTASSIUM ION, STRONTIUM ION, ...
Authors:Tomchick, D.R., Dodd, D.W., Gagnon, K.T., Corey, D.R.
Deposit date:2015-11-20
Release date:2016-02-24
Last modified:2016-03-16
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Pathogenic C9ORF72 Antisense Repeat RNA Forms a Double Helix with Tandem C:C Mismatches.
Biochemistry, 55, 2016
5EW7
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CRYSTAL STRUCTURE OF C9ORF72 ANTISENSE CCCCGG REPEAT RNA ASSOCIATED WITH LOU GEHRIG'S DISEASE AND FRONTOTEMPORAL DEMENTIA, CRYSTALLIZED WITH BA2+
Descriptor:RNA (5'-R(*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*GP*GP*CP*CP*CP*C)-3'), POTASSIUM ION, MAGNESIUM ION, ...
Authors:Tomchick, D.R., Dodd, D.W., Gagnon, K.T., Corey, D.R.
Deposit date:2015-11-20
Release date:2016-02-24
Last modified:2016-03-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Pathogenic C9ORF72 Antisense Repeat RNA Forms a Double Helix with Tandem C:C Mismatches.
Biochemistry, 55, 2016
5UE8
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THE CRYSTAL STRUCTURE OF MUNC13-1 C1C2BMUN DOMAIN
Descriptor:Protein unc-13 homolog A, ZINC ION, CHLORIDE ION
Authors:Tomchick, D.R., Rizo, J., Xu, J.
Deposit date:2016-12-29
Release date:2017-02-15
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.
Elife, 6, 2017
5UF7
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CRYSTAL STRUCTURE OF MUNC13-1 MUN DOMAIN
Descriptor:Protein unc-13 homolog A
Authors:Tomchick, D.R., Rizo, J., Xu, J.
Deposit date:2017-01-03
Release date:2017-02-15
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.896 Å)
Cite:Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.
Elife, 6, 2017
6ANJ
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SYNAPTOTAGMIN-7, C2A DOMAIN
Descriptor:Synaptotagmin-7, CALCIUM ION, TERTIARY-BUTYL ALCOHOL, ...
Authors:Tomchick, D.R., Rizo, J., Voleti, R.
Deposit date:2017-08-13
Release date:2017-09-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ANK
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SYNAPTOTAGMIN-7, C2A- AND C2B-DOMAINS
Descriptor:Synaptotagmin-7, 1,2-ETHANEDIOL, CALCIUM ION
Authors:Tomchick, D.R., Rizo, J., Voleti, R.
Deposit date:2017-08-13
Release date:2017-09-20
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.254 Å)
Cite:Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6AO5
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CRYSTAL STRUCTURE OF HUMAN MST2 IN COMPLEX WITH SAV1 SARAH DOMAIN
Descriptor:Serine/threonine-protein kinase 3, Protein salvador homolog 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Tomchick, D.R., Luo, X., Ni, L.
Deposit date:2017-08-15
Release date:2017-11-08
Method:X-RAY DIFFRACTION (2.955 Å)
Cite:SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Elife, 6, 2017
1AO0
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GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE FROM B. SUBTILIS COMPLEXED WITH ADP AND GMP
Descriptor:GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE, MAGNESIUM ION, IRON/SULFUR CLUSTER, ...
Authors:Tomchick, D.R., Smith, J.L.
Deposit date:1997-07-15
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism of the synergistic end-product regulation of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase by nucleotides.
Biochemistry, 36, 1997
2QYF
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CRYSTAL STRUCTURE OF THE MAD2/P31(COMET)/MAD2-BINDING PEPTIDE TERNARY COMPLEX
Descriptor:Mitotic spindle assembly checkpoint protein MAD2A, MAD2L1-binding protein, peptide
Authors:Tomchick, D.R., Luo, X.
Deposit date:2007-08-14
Release date:2008-01-29
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:p31comet blocks Mad2 activation through structural mimicry.
Cell(Cambridge,Mass.), 131, 2007
3BNB
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LIPOXYGENASE-1 (SOYBEAN) I553L MUTANT
Descriptor:Seed lipoxygenase-1, FE (III) ION
Authors:Tomchick, D.R.
Deposit date:2007-12-14
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BNC
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LIPOXYGENASE-1 (SOYBEAN) I553G MUTANT
Descriptor:Seed lipoxygenase-1, FE (III) ION, ACETIC ACID
Authors:Tomchick, D.R.
Deposit date:2007-12-14
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BND
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LIPOXYGENASE-1 (SOYBEAN), I553V MUTANT
Descriptor:Seed lipoxygenase-1, FE (III) ION
Authors:Tomchick, D.R.
Deposit date:2007-12-14
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BNE
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LIPOXYGENASE-1 (SOYBEAN) I553A MUTANT
Descriptor:Seed lipoxygenase-1, FE (III) ION
Authors:Tomchick, D.R.
Deposit date:2007-12-14
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Enzyme structure and dynamics affect hydrogen tunneling: the impact of a remote side chain (I553) in soybean lipoxygenase-1.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3KY9
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AUTOINHIBITED VAV1
Descriptor:Proto-oncogene vav, ZINC ION
Authors:Tomchick, D.R., Rosen, M.K., Machius, M., Yu, B.
Deposit date:2009-12-04
Release date:2010-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.731 Å)
Cite:Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1
Cell(Cambridge,Mass.), 140, 2010
3L15
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HUMAN TEAD2 TRANSCRIPTIONAL FACTOR
Descriptor:Transcriptional enhancer factor TEF-4, GLYCEROL
Authors:Tomchick, D.R., Luo, X., Tian, W.
Deposit date:2009-12-10
Release date:2010-04-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analysis of the YAP-binding domain of human TEAD2.
Proc.Natl.Acad.Sci.USA, 107, 2010