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Voltage-gated Sodium Channel 1.5 (Nav1.5) C-terminal domain in complex with Calmodulin poised for activation
Descriptor:	Calmodulin, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:	Gabelli, S.B, Bianchet, M.A, Boto, A, Jakoncic, J, Tomaselli, G.F, Amzel, L.M.
Deposit date:	2013-12-10
Release date:	2014-12-03
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Regulation of the NaV1.5 cytoplasmic domain by calmodulin. Nat Commun, 5, 2014

Nb82, a nanobody against voltage gated sodium channels Nav1.4 and Nav1.5
Descriptor:	2-(2-METHOXYETHOXY)ETHANOL, CHLORIDE ION, Nanobody Nb82, ...
Authors:	Srinivasan, L, Gabelli, S.B.
Deposit date:	2021-06-22
Release date:	2022-05-04
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Development of high-affinity nanobodies specific for Na V 1.4 and Na V 1.5 voltage-gated sodium channel isoforms. J.Biol.Chem., 298, 2022

Crystal Structure of Human Nav1.4 CTerminal Domain in Complex with apo Calmodulin
Descriptor:	1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CARBONATE ION, ...
Authors:	Yoder, J, Gabelli, S.B, Amzel, L.M.
Deposit date:	2018-08-29
Release date:	2019-04-10
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.799 Å)
Cite:	Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif. Nat Commun, 10, 2019

Crystal Structure of Human Nav1.4 C-Terminal (1599-1754) domain in complex with calcium-bound calmodulin
Descriptor:	CALCIUM ION, Calmodulin-1, Sodium channel protein type 4 subunit alpha
Authors:	Yoder, J.B, Gabelli, S.B, Amzel, L.M.
Deposit date:	2018-08-30
Release date:	2019-04-10
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (3.3 Å)
Cite:	Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif. Nat Commun, 10, 2019