Author results

1LXJ
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X-RAY STRUCTURE OF YBL001C NORTHEAST STRUCTURAL GENOMICS (NESG) CONSORTIUM TARGET YTYST72
Descriptor:HYPOTHETICAL 11.5KDA PROTEIN IN HTB2-NTH2 INTERGENIC REGION, SULFATE ION
Authors:Tao, X., Khayat, R., Christendat, D., Savchenko, A., Xu, X., Edwards, A., Arrowsmith, C.H., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2002-06-05
Release date:2003-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:CRYSTAL STRUCTURES OF MTH1187 AND ITS YEAST ORTHOLOG YBL001C
Proteins, 52, 2003
1LXN
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X-RAY STRUCTURE OF MTH1187 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT272
Descriptor:HYPOTHETICAL PROTEIN MTH1187, SULFATE ION
Authors:Tao, X., Khayat, R., Christendat, D., Savchenko, A., Xu, X., Edwards, A., Arrowsmith, C.H., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2002-06-05
Release date:2003-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structures of MTH1187 and its Yeast Ortholog YBL001C
Proteins, 52, 2003
1O77
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CRYSTAL STRUCTURE OF THE C713S MUTANT OF THE TIR DOMAIN OF HUMAN TLR2
Descriptor:TOLL-LIKE RECEPTOR 2
Authors:Tao, X., Xu, Y., Ye, Z., Beg, A.A., Tong, L.
Deposit date:2002-10-24
Release date:2002-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:An Extensively Associated Dimer in the Structure of the C713S Mutant of the Tir Domain of Human Tlr2
Biochem.Biophys.Res.Commun., 299, 2002
1PDV
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CRYSTAL STRUCTURE OF HUMAN DJ-1, P 31 2 1 SPACE GROUP
Descriptor:DJ-1
Authors:Tao, X., Tong, L.
Deposit date:2003-05-20
Release date:2003-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease.
J.Biol.Chem., 278, 2003
1PDW
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CRYSTAL STRUCTURE OF HUMAN DJ-1, P 1 21 1 SPACE GROUP
Descriptor:DJ-1
Authors:Tao, X., Tong, L.
Deposit date:2003-05-20
Release date:2003-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease.
J.Biol.Chem., 278, 2003
1PE0
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CRYSTAL STRUCTURE OF THE K130R MUTANT OF HUMAN DJ-1
Descriptor:DJ-1
Authors:Tao, X., Tong, L.
Deposit date:2003-05-20
Release date:2003-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease.
J.Biol.Chem., 278, 2003
1PJ2
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE MALATE, COFACTOR NADH, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE
Descriptor:NAD-dependent malic enzyme, mitochondrial, (2S)-2-hydroxybutanedioic acid, ...
Authors:Tao, X., Yang, Z., Tong, L.
Deposit date:2003-05-30
Release date:2003-11-11
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism.
Structure, 11, 2003
1PJ3
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE PYRUVATE, COFACTOR NAD+, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE.
Descriptor:NAD-dependent malic enzyme, mitochondrial, MANGANESE (II) ION, ...
Authors:Tao, X., Yang, Z., Tong, L.
Deposit date:2003-05-30
Release date:2003-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism.
Structure, 11, 2003
1PJ4
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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME IN A PENTARY COMPLEX WITH NATURAL SUBSTRATE MALATE, ATP, MN++, AND ALLOSTERIC ACTIVATOR FUMARATE.
Descriptor:NAD-dependent malic enzyme, mitochondrial, D-MALATE, ...
Authors:Tao, X., Yang, Z., Tong, L.
Deposit date:2003-05-31
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism.
Structure, 11, 2003
2OUC
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CRYSTAL STRUCTURE OF THE MAP KINASE BINDING DOMAIN OF MKP5
Descriptor:Dual specificity protein phosphatase 10
Authors:Tao, X., Tong, L.
Deposit date:2007-02-10
Release date:2007-08-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the MAP kinase binding domain and the catalytic domain of human MKP5.
Protein Sci., 16, 2007
2OUD
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN MKP5
Descriptor:Dual specificity protein phosphatase 10, CHLORIDE ION
Authors:Tao, X., Tong, L.
Deposit date:2007-02-10
Release date:2007-08-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the MAP kinase binding domain and the catalytic domain of human MKP5.
Protein Sci., 16, 2007
3JYC
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CRYSTAL STRUCTURE OF THE EUKARYOTIC STRONG INWARD-RECTIFIER K+ CHANNEL KIR2.2 AT 3.1 ANGSTROM RESOLUTION
Descriptor:Inward-rectifier K+ channel Kir2.2, POTASSIUM ION
Authors:Tao, X.
Deposit date:2009-09-21
Release date:2010-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 A resolution.
Science, 326, 2009
3LNM
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F233W MUTANT OF THE KV2.1 PADDLE-KV1.2 CHIMERA CHANNEL
Descriptor:Voltage-gated potassium channel subunit beta-2, F233W mutant of the Kv2.1 paddle-Kv1.2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Tao, X., Lee, A., Limapichat, W., Dougherty, D.A., MacKinnon, R.
Deposit date:2010-02-02
Release date:2010-04-14
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A gating charge transfer center in voltage sensors.
Science, 328, 2010
5TJ6
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CA2+ BOUND APLYSIA SLO1
Descriptor:High conductance calcium-activated potassium channel, POTASSIUM ION, MAGNESIUM ION, ...
Authors:MacKinnon, R., Tao, X., Hite, R.K.
Deposit date:2016-10-03
Release date:2016-12-14
Last modified:2017-09-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the open high-conductance Ca(2+)-activated K(+) channel.
Nature, 541, 2017
1DPR
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STRUCTURES OF THE APO-AND METAL ION ACTIVATED FORMS OF THE DIPHTHERIA TOX REPRESSOR FROM CORYNEBACTERIUM DIPHTHERIAE
Descriptor:DIPHTHERIA TOX REPRESSOR
Authors:Schiering, N., Tao, X., Murphy, J., Petsko, G.A., Ringe, D.
Deposit date:1995-02-06
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae.
Proc.Natl.Acad.Sci.USA, 92, 1995
5BXJ
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COMPLEX OF THE FK1 DOMAIN MUTANT A19T OF FKBP51 WITH 4-NITROPHENOL
Descriptor:Peptidyl-prolyl cis-trans isomerase FKBP5, P-NITROPHENOL
Authors:Wu, D., Tao, X., Chen, Z., Han, J., Jia, W., Li, X., Wang, Z., He, Y.X.
Deposit date:2015-06-09
Release date:2016-05-25
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of androgen receptor and inhibits androgen receptor signaling in human cells
J. Hazard. Mater., 307, 2016
1FYV
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CRYSTAL STRUCTURE OF THE TIR DOMAIN OF HUMAN TLR1
Descriptor:TOLL-LIKE RECEPTOR 1
Authors:Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J.L., Tong, L.
Deposit date:2000-10-03
Release date:2000-11-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Nature, 408, 2000
1FYW
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CRYSTAL STRUCTURE OF THE TIR DOMAIN OF HUMAN TLR2
Descriptor:TOLL-LIKE RECEPTOR 2
Authors:Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J.L., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2000-10-03
Release date:2000-11-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Nature, 408, 2000
1FYX
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CRYSTAL STRUCTURE OF P681H MUTANT OF TIR DOMAIN OF HUMAN TLR2
Descriptor:TOLL-LIKE RECEPTOR 2
Authors:Xu, Y., Tao, X., Shen, B., Horng, T., Medzhitov, R., Manley, J.L., Tong, L.
Deposit date:2000-10-03
Release date:2000-11-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.
Nature, 408, 2000
2GVG
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CRYSTAL STRUCTURE OF HUMAN NMPRTASE AND ITS COMPLEX WITH NMN
Descriptor:Nicotinamide phosphoribosyltransferase, PHOSPHATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE
Authors:Khan, J.A., Tao, X., Tong, L.
Deposit date:2006-05-02
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.
Nat.Struct.Mol.Biol., 13, 2006
2GVJ
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CRYSTAL STRUCTURE OF HUMAN NMPRTASE IN COMPLEX WITH FK866
Descriptor:Nicotinamide phosphoribosyltransferase, (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide
Authors:Khan, J.A., Tao, X., Tong, L.
Deposit date:2006-05-02
Release date:2006-06-20
Last modified:2016-11-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.
Nat.Struct.Mol.Biol., 13, 2006
2GVL
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CRYSTAL STRUCTURE OF MURINE NMPRTASE
Descriptor:Nicotinamide phosphoribosyltransferase
Authors:Khan, J.A., Tao, X., Tong, L.
Deposit date:2006-05-02
Release date:2006-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.
Nat.Struct.Mol.Biol., 13, 2006
2JS7
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SOLUTION NMR STRUCTURE OF HUMAN MYELOID DIFFERENTIATION PRIMARY RESPONSE (MYD88). NORTHEAST STRUCTURAL GENOMICS TARGET HR2869A
Descriptor:Myeloid differentiation primary response protein MyD88
Authors:Rossi, P., Ramelot, T.A., Tao, X., Ciano, M., Ho, C., Ma, L.-C., Xiao, R., Acton, T.B., Kennedy, M.A., Tong, L., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-06-29
Release date:2007-10-23
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Solution NMR Structure of Human Myeloid Differentiation Primary Response (MyD88).
To be Published
2R9R
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SHAKER FAMILY VOLTAGE DEPENDENT POTASSIUM CHANNEL (KV1.2-KV2.1 PADDLE CHIMERA CHANNEL) IN ASSOCIATION WITH BETA SUBUNIT
Descriptor:Voltage-gated potassium channel subunit beta-2, Paddle chimera voltage gated potassium channel Kv1.2-Kv2.1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Long, S.B., Tao, X., Campbell, E.B., Mackinnon, R.
Deposit date:2007-09-13
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment.
Nature, 450, 2007
3SPC
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INWARD RECTIFIER POTASSIUM CHANNEL KIR2.2 IN COMPLEX WITH DIOCTANOYLGLYCEROL PYROPHOSPHATE (DGPP)
Descriptor:Inward-rectifier K+ channel Kir2.2, POTASSIUM ION, (2R)-3-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}propane-1,2-diyl dioctanoate
Authors:Hansen, S.B., Tao, X., MacKinnon, R.
Deposit date:2011-07-01
Release date:2011-08-24
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2.454 Å)
Cite:Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
Nature, 477, 2011
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