1O77

CRYSTAL STRUCTURE OF THE C713S MUTANT OF THE TIR DOMAIN OF HUMAN TLR2

Summary for 1O77

• Entry DOI: 10.2210/pdb1o77/pdb
• Related: 1FYW
• Descriptor: TOLL-LIKE RECEPTOR 2 (1 entity in total)
• Functional Keywords: immune system/membrane protein, known biological activity receptor, immune response, inflammatory response, transmembrane, leucine-rich repeat, glycoprotein, 3d-structure., immune system-membrane protein complex
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Membrane; Single-pass type I membrane protein (By similarity): O60603
• Total number of polymer chains: 5
• Total formula weight: 87620.71

Authors

Tao, X.,Xu, Y.,Ye, Z.,Beg, A.A.,Tong, L. (deposition date: 2002-10-24, release date: 2002-11-21, Last modification date: 2023-12-13)

• Primary citation: Tao, X.,Xu, Y.,Zheng, Y.,Beg, A.A.,Tong, L.; An Extensively Associated Dimer in the Structure of the C713S Mutant of the Tir Domain of Human Tlr2; Biochem.Biophys.Res.Commun., 299:216-, 2002; PubMed: 12437972; DOI: 10.1016/S0006-291X(02)02581-0

Experimental method

X-RAY DIFFRACTION (3.2 Å)