Author results

1KPM
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FIRST STRUCTURAL EVIDENCE OF A SPECIFIC INHIBITION OF PHOSPHOLIPASE A2 BY VITAMIN E AND ITS IMPLICATIONS IN INFLAMMATION: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND VITAMIN E AT 1.8 A RESOLUTION.
Descriptor:Phospholipase A2, VITAMIN E, ACETIC ACID
Authors:Chandra, V., Jasti, J., Kaur, P., Betzel, C., Srinivasan, A., Singh, T.P.
Deposit date:2002-01-01
Release date:2002-07-10
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:First Structural Evidence of a Specific Inhibition of Phospholipase A2 by alpha-Tocopherol (Vitamin E) and its Implications in Inflammation: Crystal Structure of the Complex Formed Between Phospholipase A2 and alpha-Tocopherol at 1.8 A Resolution
J.Mol.Biol., 320, 2002
1B1U
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CRYSTAL STRUCTURE OF THE BIFUNCTIONAL INHIBITOR RAGI
Descriptor:PROTEIN (ALPHA-AMYLASE/TRYPSIN INHIBITOR RATI)
Authors:Gourinath, S., Srinivasan, A., Singh, T.P.
Deposit date:1998-11-23
Release date:1998-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the bifunctional inhibitor of trypsin and alpha-amylase from ragi seeds at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 56, 2000
1CE2
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STRUCTURE OF DIFERRIC BUFFALO LACTOFERRIN AT 2.5A RESOLUTION
Descriptor:PROTEIN (LACTOFERRIN), FE (III) ION, CARBONATE ION
Authors:Karthikeyan, S., Paramasivam, M., Yadav, S., Srinivasan, A., Singh, T.P.
Deposit date:1999-03-13
Release date:1999-03-19
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of buffalo lactoferrin at 2.5 A resolution using crystals grown at 303 K shows different orientations of the N and C lobes.
Acta Crystallogr.,Sect.D, 55, 1999
1FV0
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FIRST STRUCTURAL EVIDENCE OF THE INHIBITION OF PHOSPHOLIPASE A2 BY ARISTOLOCHIC ACID: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND ARISTOLOCHIC ACID
Descriptor:PHOSPHOLIPASE A2, SULFATE ION, ACETATE ION, ...
Authors:Chandra, V., Jasti, J., Kaur, P., Srinivasan, A., Betzel, C., Singh, T.P.
Deposit date:2000-09-18
Release date:2002-08-28
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Phospholipase A2 Inhibition for the Synthesis of Prostaglandins by the Plant Alkaloid Aristolochic Acid from a 1.7 A Crystal Structure
Biochemistry, 41, 2002
1MF4
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STRUCTURE-BASED DESIGN OF POTENT AND SELECTIVE INHIBITORS OF PHOSPHOLIPASE A2: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSHOLIPASE A2 FROM NAJA NAJA SAGITTIFERA AND A DESIGNED PEPTIDE INHIBITOR AT 1.9 A RESOLUTION
Descriptor:Phospholipase A2, VAL-ALA-PHE-ARG-SER, CALCIUM ION
Authors:Singh, R.K., Vikram, P., Paramsivam, M., Jabeen, T., Sharma, S., Makker, J., Dey, S., Kaur, P., Srinivasan, A., Singh, T.P.
Deposit date:2002-08-09
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features
Biochemistry, 42, 2003
1N76
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CRYSTAL STRUCTURE OF HUMAN SEMINAL LACTOFERRIN AT 3.4 A RESOLUTION
Descriptor:LACTOFERRIN, SODIUM ION, FE (III) ION, ...
Authors:Kumar, J., Weber, W., Munchau, S., Yadav, S., Singh, S.B., Sarvanan, K., Paramsivam, M., Sharma, S., Kaur, P., Bhushan, A., Srinivasan, A., Betzel, C., Singh, T.P.
Deposit date:2002-11-12
Release date:2003-02-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of human seminal lactoferrin at 3.4A resolution
Indian J.Biochem.Biophys., 40, 2003
2QJE
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CRYSTAL STRUCTURE OF THE COMPLEX OF BOVINE C-LOBE WITH AMYGDALIN AT 2.3A RESOLUTION
Descriptor:Lactotransferrin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Mir, R., Jain, R., Kumar, S., Sinha, M., Singh, N., Sharma, S., Kaur, P., Srinivasan, A., Bhushan, A., Singh, T.P.
Deposit date:2007-07-07
Release date:2008-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the complex of Bovine C-lobe with Amygdalin at 2.3A resolution
To be Published
2RD4
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DESIGN OF SPECIFIC INHIBITORS OF PHOSPHOLIPASE A2: CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOLIPASE A2 WITH PENTAPEPTIDE LEU-VAL-PHE-PHE-ALA AT 2.9 A RESOLUTION
Descriptor:Phospholipase A2 isoform 1, Phospholipase A2 isoform 2, pentapeptide inhibitor, ...
Authors:Mirza, Z., Kaur, A., Singh, N., Sinha, M., Sharma, S., Srinivasan, A., Kaur, P., Singh, T.P.
Deposit date:2007-09-21
Release date:2007-10-09
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Design of specific inhibitors of Phospholipase A2: Crystal structure of the complex of phospholipase A2 with pentapeptide Leu-Val-Phe-Phe-Ala at 2.9 A resolution
To be Published
2Z5Z
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CRYSTAL STRUCTURE OF THE COMPLEX OF BUFFALO LACTOPEROXIDASE WITH FLUORIDE ION AT 3.5A RESOLUTION
Descriptor:Lactoperoxidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Sheikh, I.A., Jain, R., Singh, N., Sharma, S., Bhushan, A., Kaur, P., Srinivasan, A., Singh, T.P.
Deposit date:2007-07-20
Release date:2007-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the complex of buffalo Lactoperoxidase with fluoride ion at 3.5A resolution
To be Published
3D5H
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CRYSTAL STRUCTURE OF HAEMENTHIN FROM HAEMANTHUS MULTIFLORUS AT 2.0A RESOLUTION: FORMATION OF A NOVEL LOOP ON A TIM BARREL FOLD AND ITS FUNCTIONAL SIGNIFICANCE
Descriptor:Haementhin, ACETATE ION, PHOSPHATE ION
Authors:Kumar, S., Singh, N., Sinha, M., Singh, S.B., Bhushan, A., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P.
Deposit date:2008-05-16
Release date:2009-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of haementhin from Haemanthus multiflorus at 2.0A resolution: Formation of a novel loop on a TIM barrel fold and its functional significance
To be Published
3ERH
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FIRST STRUCTURAL EVIDENCE OF SUBSTRATE SPECIFICITY IN MAMMALIAN PEROXIDASES: CRYSTAL STRUCTURES OF SUBSTRATE COMPLEXES WITH LACTOPEROXIDASES FROM TWO DIFFERENT SPECIES
Descriptor:Lactoperoxidase, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION, ...
Authors:Sheikh, I.A., Singh, N., Singh, A.K., Sinha, M., Singh, S.B., Bhushan, A., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P.
Deposit date:2008-10-02
Release date:2009-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Evidence of Substrate Specificity in Mammalian Peroxidases: STRUCTURE OF THE THIOCYANATE COMPLEX WITH LACTOPEROXIDASE AND ITS INTERACTIONS AT 2.4 A RESOLUTION
J.Biol.Chem., 284, 2009
3ERI
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FIRST STRUCTURAL EVIDENCE OF SUBSTRATE SPECIFICITY IN MAMMALIAN PEROXIDASES: CRYSTAL STRUCTURES OF SUBSTRATE COMPLEXES WITH LACTOPEROXIDASES FROM TWO DIFFERENT SPECIES
Descriptor:Lactoperoxidase, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION, ...
Authors:Singh, A.K., Singh, N., Sheikh, I.A., Sinha, M., Bhushan, A., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P.
Deposit date:2008-10-02
Release date:2009-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Evidence of Substrate Specificity in Mammalian Peroxidases: STRUCTURE OF THE THIOCYANATE COMPLEX WITH LACTOPEROXIDASE AND ITS INTERACTIONS AT 2.4 A RESOLUTION
J.Biol.Chem., 284, 2009
3FG5
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CRYSTAL STRUCTURE DETERMINATION OF A TERNARY COMPLEX OF PHOSPHOLIPASE A2 WITH A PENTAPEPTIDE FLSYK AND AJMALINE AT 2.5 A RESOLUTION
Descriptor:Group II Phospholipase A2, pentapeptide FLSYK, AJMALINE
Authors:Kumar, M., Kumar, S., Vikram, G., Singh, N., Sinha, M., Bhushan, A., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P.
Deposit date:2008-12-05
Release date:2008-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure determination of a ternary complex of phospholipase A2 with a pentapeptide FLSYK and Ajmaline at 2.5 A resolution
To be Published
3GCI
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN A NEW ISOFORM OF PHOSPHOLIPASE A2 WITH C-TERMINAL AMYLOID BETA HEPTAPEPTIDE AT 2 A RESOLUTION
Descriptor:Phospholipase A2 isoform 3, Heptapeptide from Amyloid beta A4 protein, CALCIUM ION
Authors:Mirza, Z., Vikram, G., Singh, N., Sinha, M., Bhushan, A., Sharma, S., Srinivasan, A., Kaur, P., Singh, T.P.
Deposit date:2009-02-22
Release date:2009-03-10
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Crystal Structure of the Complex Formed Between a New Isoform of Phospholipase A2 with C-terminal Amyloid Beta Heptapeptide at 2 A Resolution
To be Published
3GCK
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MODE OF LIGAND BINDING AND ASSIGNMENT OF SUBSITES IN MAMMALIAN PEROXIDASES: CRYSTAL STRUCTURE OF LACTOPEROXIDASE COMPLEXES WITH ACETYL SALYCYLIC ACID, SALICYLHYDROXAMIC ACID AND BENZYLHYDROXAMIC ACID
Descriptor:Lactoperoxidase, PROTOPORPHYRIN IX CONTAINING FE, CALCIUM ION, ...
Authors:Singh, A.K., Singh, N., Sinha, M., Bhushan, A., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P.
Deposit date:2009-02-22
Release date:2009-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mode of ligand binding and assignment of subsites in mammalian peroxidases: crystal structure of lactoperoxidase complexes with acetyl salycylic acid, salicylhydroxamic acid and benzylhydroxamic acid
To be Published
3HU7
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STRUCTURAL CHARACTERIZATION AND BINDING STUDIES OF A PLANT PATHOGENESIS RELATED PROTEIN HEAMANTHIN FROM HAEMANTHUS MULTIFLORUS REVEAL ITS DUAL INHIBITORY EFFECTS AGAINST XYLANASE AND ALPHA-AMYLASE
Descriptor:Haementhin, ACETATE ION, PHOSPHATE ION
Authors:Kumar, S., Singh, N., Sinha, M., Bhushan, A., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P.
Deposit date:2009-06-13
Release date:2010-04-28
Last modified:2011-09-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure determination and inhibition studies of a novel xylanase and alpha-amylase inhibitor protein (XAIP) from Scadoxus multiflorus.
Febs J., 277, 2010
3JQ5
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PHOSPHOLIPASE A2 PREVENTS THE AGGREGATION OF AMYLOID BETA PEPTIDES: CRYSTAL STRUCTURE OF THE COMPLEX OF PHOSPHOLIPASE A2 WITH OCTAPEPTIDE FRAGMENT OF AMYLOID BETA PEPTIDE, ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER AT 2 A RESOLUTION
Descriptor:Phospholipase A2 isoform 3, Amyloid Beta Peptide, CALCIUM ION
Authors:Mirza, Z., Vikram, G., Singh, N., Sinha, M., Bhushan, A., Sharma, S., Srinivasan, A., Kaur, P., Singh, T.P.
Deposit date:2009-09-06
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Phospholipase A2 Prevents the Aggregation of Amyloid Beta Peptides: Crystal Structure of the Complex of Phospholipase A2 with Octapeptide Fragment of Amyloid Beta Peptide, Asp-Ala-Glu-Phe-Arg-His-Asp-Ser at 2 A Resolution
To be Published
3JTI
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 WITH BETA-AMYLOID FRAGMENT, LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET AT 1.8 A RESOLUTION
Descriptor:Phospholipase A2 isoform 3, octapeptide from Amyloid beta A4 protein, CALCIUM ION
Authors:Pandey, N., Mirza, Z., Vikram, G., Singh, N., Bhushan, A., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P.
Deposit date:2009-09-12
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution
To be Published
3OSZ
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CRYSTAL STRUCTURE OF THE COMPLEX OF PROTEINASE K WITH AN ANTIMICROBIAL NONAPEPTIDE, AT 2.26 A RESOLUTION
Descriptor:Proteinase K, 10-mer peptide, CALCIUM ION, ...
Authors:Singh, A., Sinha, M., Bhushan, A., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P.
Deposit date:2010-09-10
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal Structure of the complex of proteinase K with an antimicrobial nonapeptide, at 2.26 A resolution
To be Published
3PUD
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CRYSTAL STRUCTURE OF DHYDRODIPICOLINATE SYNTHASE FROM ACINETOBACTER BAUMANNII AT 2.8A RESOLUTION
Descriptor:Dihydrodipicolinate synthase, SULFATE ION, GLYCEROL
Authors:Jithesh, O., Yamini, S., Kaur, N., Gautam, A., Tewari, R., Kushwaha, G.S., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P.
Deposit date:2010-12-04
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of Dhydrodipicolinate synthase from Acinetobacter baumannii at 2.8A resolution
To be Published
3PUE
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CRYSTAL STRUCTURE OF THE COMPLEX OF DHYDRODIPICOLINATE SYNTHASE FROM ACINETOBACTER BAUMANNII WITH LYSINE AT 2.6A RESOLUTION
Descriptor:Dihydrodipicolinate synthase, SULFATE ION, LYSINE, ...
Authors:Jithesh, O., Yamini, S., Kaur, N., Gautam, A., Tewari, R., Kushwaha, G.S., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P.
Deposit date:2010-12-04
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the complex of Dhydrodipicolinate synthase from Acinetobacter baumannii with lysine at 2.6A resolution
To be Published
3PUL
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CRYSTAL STRUCTURE OF THE COMPLEX OF DHYDRODIPICOLINATE SYNTHASE FROM ACINETOBACTER BAUMANNII WITH LYSINE AT 2.3A RESOLUTION
Descriptor:Dihydrodipicolinate synthase, GLYCEROL, SULFATE ION, ...
Authors:Jithesh, O., Yamini, S., Kaur, N., Gautam, A., Tewari, R., Kushwaha, G.S., Kaur, P., Srinivasan, A., Sharma, S., Singh, T.P.
Deposit date:2010-12-06
Release date:2010-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the complex of Dhydrodipicolinate synthase from Acinetobacter baumannii with lysine at 2.3A resolution
to be published
2DT0
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CRYSTAL STRUCTURE OF THE COMPLEX OF GOAT SIGNALLING PROTEIN WITH THE TRIMER OF N-ACETYLGLUCOSAMINE AT 2.45A RESOLUTION
Descriptor:Chitinase-3-like protein 1, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Kumar, J., Ethayathulla, A.S., Srivastava, D.B., Singh, N., Sharma, S., Bhushan, A., Srinivasan, A., Singh, T.P.
Deposit date:2006-07-09
Release date:2006-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Carbohydrate-binding properties of goat secretory glycoprotein (SPG-40) and its functional implications: structures of the native glycoprotein and its four complexes with chitin-like oligosaccharides
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
2R5L
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CRYSTAL STRUCTURE OF LACTOPEROXIDASE AT 2.4A RESOLUTION
Descriptor:Lactoperoxidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Singh, A.K., Singh, N., Sharma, S., Kaur, P., Srinivasan, A., Singh, T.P.
Deposit date:2007-09-04
Release date:2007-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Lactoperoxidase at 2.4 A Resolution.
J.Mol.Biol., 376, 2007
3FAQ
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CRYSTAL STRUCTURE OF LACTOPEROXIDASE COMPLEX WITH CYANIDE
Descriptor:Lactoperoxidase, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION, ...
Authors:Sheikh, I.A., Singh, N., Sharma, S., Kaur, P., Srinivasan, A., Singh, T.P.
Deposit date:2008-11-18
Release date:2009-03-31
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Evidence of Substrate Specificity in Mammalian Peroxidases: STRUCTURE OF THE THIOCYANATE COMPLEX WITH LACTOPEROXIDASE AND ITS INTERACTIONS AT 2.4 A RESOLUTION
J.Biol.Chem., 284, 2009