Author results

6C5V
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AN ANTI-GH/GL ANTIBODY THAT NEUTRALIZES DUAL-TROPIC INFECTION DEFINES A SITE OF VULNERABILITY ON EPSTEIN-BARR VIRUS
Descriptor:Envelope glycoprotein H, Envelope glycoprotein L, Glycoprotein 42, ...
Authors:Snijder, J., Ortego, M.S., Weidle, C., Stuart, A.B., Gray, M.A., McElrath, M.J., Pancera, M., Veesler, D., McGuire, A.T., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-01-16
Release date:2018-05-02
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
5N8Y
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KAICBA CIRCADIAN CLOCK BACKBONE MODEL BASED ON A CRYO-EM DENSITY
Descriptor:Circadian clock protein kinase KaiC, Circadian clock protein KaiB, Circadian clock protein KaiA
Authors:Schuller, J.M., Snijder, J., Loessl, P., Heck, A.J.R., Foerster, F.
Deposit date:2017-02-24
Release date:2017-03-29
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structures of the cyanobacterial circadian oscillator frozen in a fully assembled state.
Science, 355, 2017
6NB5
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CRYSTAL STRUCTURE OF ANTI- MERS-COV HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT
Descriptor:LCA60 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB8
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CRYSTAL STRUCTURE OF ANTI- SARS-COV HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT
Descriptor:S230 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
5SZS
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GLYCAN SHIELD AND EPITOPE MASKING OF A CORONAVIRUS SPIKE PROTEIN OBSERVED BY CRYO-ELECTRON MICROSCOPY
Descriptor:Spike glycoprotein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Walls, A.C., Tortorici, M.A., Frenz, B., Snijder, J., Li, W., Rey, F.A., DiMaio, F., Bosch, B.J., Veesler, D.
Deposit date:2016-08-15
Release date:2016-09-14
Last modified:2017-11-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy.
Nat.Struct.Mol.Biol., 23, 2016
6B3O
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TECTONIC CONFORMATIONAL CHANGES OF A CORONAVIRUS SPIKE GLYCOPROTEIN PROMOTE MEMBRANE FUSION
Descriptor:Spike glycoprotein
Authors:Walls, A.C., Tortorici, M.A., Snijder, J., Xiong, X., Bosch, B.J., Rey, F.A., Veesler, D.
Deposit date:2017-09-22
Release date:2017-10-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6MYY
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GERMLINE VRC01 ANTIBODY RECOGNITION OF A MODIFIED CLADE C HIV-1 ENVELOPE TRIMER, 3 FABS BOUND, SHARPENED MAP
Descriptor:426c DS-SOSIP D3, VRC01GL light chain, VRC01GL heavy chain, ...
Authors:Borst, A.J., Weidle, C.E., Gray, M.D., Frenz, B., Snijder, J., Joyce, M.G., Georgiev, I.S., Stewart-Jones, G.B.E., Kwong, P.D., McGuire, A.T., DiMaio, F., Stamatatos, L., Pancera, M., Veesler, D.
Deposit date:2018-11-02
Release date:2018-11-14
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
6MZJ
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GERMLINE VRC01 ANTIBODY RECOGNITION OF A MODIFIED CLADE C HIV-1 ENVELOPE TRIMER, 2 FABS BOUND, SHARPENED MAP
Descriptor:426c DS-SOSIP D3, VRC01GL light chain, VRC01GL heavy chain, ...
Authors:Borst, A.J., Weidle, C.E., Gray, M.D., Frenz, B., Snijder, J., Joyce, M.G., Georgiev, I.S., Stewart-Jones, G.B.E., Kwong, P.D., McGuire, A.T., DiMaio, F., Stamatatos, L., Pancera, M., Veesler, D.
Deposit date:2018-11-05
Release date:2018-11-14
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
6BLA
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STRUCTURE OF AMM01 FAB, AN ANTI EBV GH/GL NEUTRALIZING ANTIBODY
Descriptor:AMM01 Fab Heavy chain, AMM01 Fab Light chain, 1,2-ETHANEDIOL, ...
Authors:Pancera, M., Weidle, C.
Deposit date:2017-11-09
Release date:2018-04-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
6NB3
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MERS-COV COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, LCA60 light chain, LCA60 heavy chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB4
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MERS-COV S COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, LCA60 heavy chain, LCA60 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB6
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SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB7
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SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6BFU
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GLYCAN SHIELD AND FUSION ACTIVATION OF A DELTACORONAVIRUS SPIKE GLYCOPROTEIN FINE-TUNED FOR ENTERIC INFECTIONS
Descriptor:Spike protein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Xiong, X., Tortorici, M.A., Snijder, S., Yoshioka, C., Walls, A.C., Li, W., Seattle Structural Genomics Center for Infectious Disease (SSGCID), McGuire, A.T., Rey, F.A., Bosch, B.J., Veesler, D.
Deposit date:2017-10-27
Release date:2017-11-22
Last modified:2019-04-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections.
J. Virol., 92, 2018
5LF5
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MYELIN-ASSOCIATED GLYCOPROTEIN (MAG) DEGLYCOSYLATED FULL EXTRACELLULAR DOMAIN WITH CO-PURIFIED LIGAND
Descriptor:Myelin-associated glycoprotein, ALPHA-D-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Pronker, M.F., Janssen, B.J.C.
Deposit date:2016-06-30
Release date:2016-12-14
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of myelin-associated glycoprotein adhesion and signalling.
Nat Commun, 7, 2016
5LFR
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CRYSTAL STRUCTURE OF GLYCOSYLATED MYELIN-ASSOCIATED GLYCOPROTEIN (MAG) IG1-3
Descriptor:Myelin-associated glycoprotein, ALPHA-D-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Pronker, M.F., Janssen, B.J.C.
Deposit date:2016-07-04
Release date:2016-12-14
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural basis of myelin-associated glycoprotein adhesion and signalling.
Nat Commun, 7, 2016
5LFU
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MYELIN-ASSOCIATED GLYCOPROTEIN (MAG) GLYCOSYLATED AND LYSINE-METHYLATED FULL EXTRACELLULAR DOMAIN
Descriptor:Myelin-associated glycoprotein, ALPHA-D-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Pronker, M.F., Janssen, B.J.C.
Deposit date:2016-07-04
Release date:2016-12-14
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Structural basis of myelin-associated glycoprotein adhesion and signalling.
Nat Commun, 7, 2016
5LFV
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CRYSTAL STRUCTURE OF GLYCOSYLATED MYELIN-ASSOCIATED GLYCOPROTEIN (MAG) IG1-3 WITH SOAKED TRISACCHARIDE LIGAND
Descriptor:Myelin-associated glycoprotein, ALPHA-D-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Pronker, M.F., Janssen, B.J.C.
Deposit date:2016-07-04
Release date:2016-12-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of myelin-associated glycoprotein adhesion and signalling.
Nat Commun, 7, 2016
6MFT
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CRYSTAL STRUCTURE OF GLYCOSYLATED 426C HIV-1 GP120 CORE G459C IN COMPLEX WITH GLVRC01 A60C HEAVY CHAIN
Descriptor:Heavy Chain glVRC01, Light chain glVRC01, Gp120, ...
Authors:Weidle, C., Pancera, M., Stamatatos, L., Gray, M.
Deposit date:2018-09-12
Release date:2018-11-14
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.315 Å)
Cite:Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018