Author results

1BIQ
  • Download 1biq
  • View 1biq
Molmil generated image of 1biq
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN MUTANT E238A
Descriptor:PROTEIN R2 OF RIBONUCLEOTIDE REDUCTASE, FE (II) ION, FE (III) ION, ...
Authors:Logan, D.T., Demare, F., Persson, B.O., Slaby, A., Sjoberg, B.M., Nordlund, P.
Deposit date:1998-06-18
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of two self-hydroxylating ribonucleotide reductase protein R2 mutants: structural basis for the oxygen-insertion step of hydroxylation reactions catalyzed by diiron proteins.
Biochemistry, 37, 1998
1KGN
  • Download 1kgn
  • View 1kgn
Molmil generated image of 1kgn
R2F FROM CORYNEBACTERIUM AMMONIAGENES IN ITS OXIDISED, FE CONTAINING, FORM
Descriptor:Ribonucleotide reductase protein R2F, FE (III) ION
Authors:Hogbom, M., Huque, Y., Sjoberg, B.M., Nordlund, P.
Deposit date:2001-11-28
Release date:2001-12-21
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes.
Biochemistry, 41, 2002
1KGO
  • Download 1kgo
  • View 1kgo
Molmil generated image of 1kgo
R2F FROM CORYNEBACTERIUM AMMONIAGENES IN ITS REDUCED, FE CONTAINING, FORM
Descriptor:Ribonucleotide reductase protein R2F, FE (II) ION
Authors:Hogbom, M., Huque, Y., Sjoberg, B.M., Nordlund, P.
Deposit date:2001-11-28
Release date:2001-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes.
Biochemistry, 41, 2002
1KGP
  • Download 1kgp
  • View 1kgp
Molmil generated image of 1kgp
R2F FROM CORYNEBACTERIUM AMMONIAGENES IN ITS MN SUBSTITUTED FORM
Descriptor:Ribonucleotide reductase protein R2F, MANGANESE (II) ION
Authors:Hogbom, M., Huque, Y., Sjoberg, B.M., Nordlund, P.
Deposit date:2001-11-28
Release date:2001-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes.
Biochemistry, 41, 2002
1RSR
  • Download 1rsr
  • View 1rsr
Molmil generated image of 1rsr
AZIDE COMPLEX OF THE DIFERROUS F208A MUTANT R2 SUBUNIT OF RIBONUCLEOTIDE REDUCTASE
Descriptor:Ribonucleoside-diphosphate reductase 1 beta chain, FE (II) ION, MERCURY (II) ION, ...
Authors:Andersson, M.E., Hogbom, M., Rinaldo-Matthis, A., Andersson, K.K., Sjoberg, B.M., Nordlund, P.
Deposit date:2003-12-10
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of an Azide Complex of the Diferrous R2 Subunit of Ribonucleotide Reductase Displays a Novel Carboxylate Shift with Important Mechanistic Implications for Diiron-Catalyzed Oxygen Activation
J.Am.Chem.Soc., 121, 1999
1RSV
  • Download 1rsv
  • View 1rsv
Molmil generated image of 1rsv
AZIDE COMPLEX OF THE DIFERROUS E238A MUTANT R2 SUBUNIT OF RIBONUCLEOTIDE REDUCTASE
Descriptor:Ribonucleoside-diphosphate reductase 1 beta chain, FE (III) ION, MERCURY (II) ION, ...
Authors:Assarsson, M., Andersson, M.E., Hogbom, M., Persson, B.O., Sahlin, M., Barra, A.L., Sjoberg, B.M., Nordlund, P., Graslund, A.
Deposit date:2003-12-10
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Restoring proper radical generation by azide binding to the iron site of the E238A mutant R2 protein of ribonucleotide reductase from Escherichia coli.
J.Biol.Chem., 276, 2001
2XOD
  • Download 2xod
  • View 2xod
Molmil generated image of 2xod
CRYSTAL STRUCTURE OF FLAVOPROTEIN NRDI FROM BACILLUS ANTHRACIS IN THE OXIDISED FORM
Descriptor:NRDI PROTEIN, FLAVIN MONONUCLEOTIDE, ZINC ION, ...
Authors:Johansson, R., Sprenger, J., Torrents, E., Sahlin, M., Sjoberg, B.M., Logan, D.T.
Deposit date:2010-08-14
Release date:2010-08-25
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:High Resolution Crystal Structures of Nrdi in the Oxidised and Reduced States: An Unusual Flavodoxin
FEBS J., 277, 2010
2XOE
  • Download 2xoe
  • View 2xoe
Molmil generated image of 2xoe
CRYSTAL STRUCTURE OF FLAVOPROTEIN NRDI FROM BACILLUS ANTHRACIS IN THE SEMIQUINONE FORM
Descriptor:NRDI PROTEIN, FLAVIN MONONUCLEOTIDE, ZINC ION, ...
Authors:Johansson, R., Sprenger, J., Torrents, E., Sahlin, M., Sjoberg, B.M., Logan, D.T.
Deposit date:2010-08-14
Release date:2010-08-25
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:High Resolution Crystal Structures of Nrdi in the Oxidised and Reduced States: An Unusual Flavodoxin
FEBS J., 277, 2010
4COI
  • Download 4coi
  • View 4coi
Molmil generated image of 4coi
CRYSTAL STRUCTURE OF THE ANAEROBIC RIBONUCLEOTIDE REDUCTASE FROM THERMOTOGA MARITIMA WITH GLYCEROL IN THE ACTIVE SITE
Descriptor:ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, ZINC ION, GLYCEROL
Authors:Aurelius, O., Johansson, R., Bagenholm, V., Beck, T., Balhuizen, A., Lundin, D., Sjoberg, B.M., Mulliez, E., Logan, D.T.
Deposit date:2014-01-28
Release date:2015-01-14
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site.
Plos One, 10, 2015
4COJ
  • Download 4coj
  • View 4coj
Molmil generated image of 4coj
CRYSTAL STRUCTURE OF THE ANAEROBIC RIBONUCLEOTIDE REDUCTASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH DATP AND CTP
Descriptor:ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, ZINC ION, CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Aurelius, O., Johansson, R., Bagenholm, V., Beck, T., Balhuizen, A., Lundin, D., Sjoberg, B.M., Mulliez, E., Logan, D.T.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site.
Plos One, 10, 2015
4COL
  • Download 4col
  • View 4col
Molmil generated image of 4col
CRYSTAL STRUCTURE OF THE ANAEROBIC RIBONUCLEOTIDE REDUCTASE FROM THERMOTOGA MARITIMA WITH DATP BOUND IN THE SPECIFICITY SITE
Descriptor:ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, ZINC ION, MAGNESIUM ION, ...
Authors:Aurelius, O., Johansson, R., Bagenholm, V., Beck, T., Balhuizen, A., Lundin, D., Sjoberg, B.M., Mulliez, E., Logan, D.T.
Deposit date:2014-01-29
Release date:2015-05-06
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site.
Plos One, 10, 2015
4COM
  • Download 4com
  • View 4com
Molmil generated image of 4com
CRYSTAL STRUCTURE OF THE ANAEROBIC RIBONUCLEOTIDE REDUCTASE FROM THERMOTOGA MARITIMA WITH MES IN THE ACTIVE SITE
Descriptor:ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Aurelius, O., Johansson, R., Bagenholm, V., Beck, T., Balhuizen, A., Lundin, D., Sjoberg, B.M., Mulliez, E., Logan, D.T.
Deposit date:2014-01-29
Release date:2015-01-14
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site.
Plos One, 10, 2015
4CON
  • Download 4con
  • View 4con
Molmil generated image of 4con
CRYSTAL STRUCTURE OF THE ANAEROBIC RIBONUCLEOTIDE REDUCTASE FROM THERMOTOGA MARITIMA WITH CITRATE IN THE ACTIVE SITE
Descriptor:ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE, CITRIC ACID
Authors:Aurelius, O., Johansson, R., Bagenholm, V., Beck, T., Balhuizen, A., Lundin, D., Sjoberg, B.M., Mulliez, E., Logan, D.T.
Deposit date:2014-01-29
Release date:2015-01-14
Last modified:2015-07-15
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The Crystal Structure of Thermotoga Maritima Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site.
Plos One, 10, 2015
5OLK
  • Download 5olk
  • View 5olk
Molmil generated image of 5olk
CRYSTAL STRUCTURE OF THE ATP-CONE-CONTAINING NRDB FROM LEEUWENHOEKIELLA BLANDENSIS
Descriptor:Ribonucleoside-diphosphate reductase, beta subunit 1, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ...
Authors:Hasan, M., Grinberg, A.R., Sjoberg, B.M., Logan, D.T.
Deposit date:2017-07-28
Release date:2018-01-10
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Novel ATP-cone-driven allosteric regulation of ribonucleotide reductase via the radical-generating subunit.
Elife, 7, 2018
6GP2
  • Download 6gp2
  • View 6gp2
Molmil generated image of 6gp2
RIBONUCLEOTIDE REDUCTASE CLASS IE R2 FROM MESOPLASMA FLORUM, DOPA-ACTIVE FORM
Descriptor:Ribonucleoside-diphosphate reductase beta chain, CALCIUM ION
Authors:Srinivas, V., Lebrette, H., Lundin, D., Kutin, Y., Sahlin, M., Lerche, M., Enrich, J., Branca, R.M.M., Cox, N., Sjoberg, B.M., Hogbom, M.
Deposit date:2018-06-05
Release date:2018-08-22
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens.
Nature, 563, 2018
6GP3
  • Download 6gp3
  • View 6gp3
Molmil generated image of 6gp3
RIBONUCLEOTIDE REDUCTASE CLASS IE R2 FROM MESOPLASMA FLORUM, INACTIVE FORM
Descriptor:Ribonucleoside-diphosphate reductase beta chain, CALCIUM ION
Authors:Srinivas, V., Lebrette, H., Lundin, D., Kutin, Y., Sahlin, M., Lerche, M., Enrich, J., Branca, R.M.M., Cox, N., Sjoberg, B.M., Hogbom, M.
Deposit date:2018-06-05
Release date:2018-08-22
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens.
Nature, 563, 2018
6SF4
  • Download 6sf4
  • View 6sf4
Molmil generated image of 6sf4
APO FORM OF THE RIBONUCLEOTIDE REDUCTASE NRDB PROTEIN FROM LEEUWENHOEKIELLA BLANDENSIS
Descriptor:Ribonucleoside-diphosphate reductase, beta subunit 1
Authors:Hasan, M., Rozman Grinberg, I., Sjoberg, B.M., Logan, D.T.
Deposit date:2019-07-31
Release date:2019-08-28
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Class Id ribonucleotide reductase utilizes a Mn2(IV,III) cofactor and undergoes large conformational changes on metal loading.
J.Biol.Inorg.Chem., 24, 2019
6SF5
  • Download 6sf5
  • View 6sf5
Molmil generated image of 6sf5
MN-CONTAINING FORM OF THE RIBONUCLEOTIDE REDUCTASE NRDB PROTEIN FROM LEEUWENHOEKIELLA BLANDENSIS
Descriptor:Ribonucleoside-diphosphate reductase, beta subunit 1, MANGANESE (II) ION
Authors:Hasan, M., Rozman Grinberg, I., Sjoberg, B.M., Logan, D.T.
Deposit date:2019-08-01
Release date:2019-08-28
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Class Id ribonucleotide reductase utilizes a Mn2(IV,III) cofactor and undergoes large conformational changes on metal loading.
J.Biol.Inorg.Chem., 24, 2019
1R1R
  • Download 1r1r
  • View 1r1r
Molmil generated image of 1r1r
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN MUTANT Y730F WITH A REDUCED ACTIVE SITE FROM ESCHERICHIA COLI
Descriptor:RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
Authors:Eriksson, M., Eklund, H.
Deposit date:1997-07-15
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Structure, 5, 1997
5R1R
  • Download 5r1r
  • View 5r1r
Molmil generated image of 5r1r
RIBONUCLEOTIDE REDUCTASE E441A MUTANT R1 PROTEIN FROM ESCHERICHIA COLI
Descriptor:RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
Authors:Eriksson, M., Eklund, H.
Deposit date:1997-09-17
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase.
J.Biol.Chem., 272, 1997
6R1R
  • Download 6r1r
  • View 6r1r
Molmil generated image of 6r1r
RIBONUCLEOTIDE REDUCTASE E441D MUTANT R1 PROTEIN FROM ESCHERICHIA COLI
Descriptor:RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
Authors:Eriksson, M., Eklund, H.
Deposit date:1997-09-17
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase.
J.Biol.Chem., 272, 1997
7R1R
  • Download 7r1r
  • View 7r1r
Molmil generated image of 7r1r
RIBONUCLEOTIDE REDUCTASE E441Q MUTANT R1 PROTEIN FROM ESCHERICHIA COLI
Descriptor:RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN
Authors:Eriksson, M., Eklund, H.
Deposit date:1997-09-17
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu441 in Escherichia coli ribonucleotide reductase.
J.Biol.Chem., 272, 1997
1RNR
  • Download 1rnr
  • View 1rnr
Molmil generated image of 1rnr
AUTOCATALYTIC GENERATION OF DOPA IN THE ENGINEERED PROTEIN R2 F208Y FROM ESCHERICHIA COLI RIBONUCLEOTIDE REDUCTASE AND CRYSTAL STRUCTURE OF THE DOPA-208 PROTEIN
Descriptor:RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, FE (III) ION, MERCURY (II) ION
Authors:Aberg, A., Nordlund, P.
Deposit date:1993-04-26
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Autocatalytic generation of dopa in the engineered protein R2 F208Y from Escherichia coli ribonucleotide reductase and crystal structure of the dopa-208 protein.
Biochemistry, 32, 1993
2R1R
  • Download 2r1r
  • View 2r1r
Molmil generated image of 2r1r
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH DTTP OCCUPYING THE SPECIFICITY SITE FROM ESCHERICHIA COLI
Descriptor:RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN, THYMIDINE-5'-TRIPHOSPHATE
Authors:Eriksson, M., Eklund, H.
Deposit date:1997-07-21
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding.
Structure, 5, 1997
3DHZ
  • Download 3dhz
  • View 3dhz
Molmil generated image of 3dhz
APO (IRON FREE) STRUCTURE OF C. AMMONIAGENES R2 PROTEIN
Descriptor:Ribonucleotide reductase subunit R2F, FE (II) ION
Authors:Hogbom, M., Nordlund, P.
Deposit date:2008-06-19
Release date:2008-07-01
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural and mutational studies of the carboxylate cluster in Iron-free Ribonucleotide Reductase R2.
Biochemistry, 43, 2004
<12>