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5SVJ
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE CLOSED, APO STATE
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-09-28
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.984 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVK
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE ATP-BOUND, OPEN STATE
Descriptor:P2X purinoceptor 3, ADENOSINE-5'-TRIPHOSPHATE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-09-28
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.773 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVL
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE ATP-BOUND, CLOSED (DESENSITIZED) STATE
Descriptor:P2X purinoceptor 3, ADENOSINE-5'-TRIPHOSPHATE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-10-05
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVM
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL BOUND TO AGONIST 2-METHYLTHIO-ATP IN THE DESENSITIZED STATE
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-06
Release date:2016-09-28
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (3.093 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVP
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ANOMALOUS SULFUR SIGNAL REVEALS THE POSITION OF AGONIST 2-METHYLTHIO-ATP BOUND TO THE ATP-GATED HUMAN P2X3 ION CHANNEL IN THE DESENSITIZED STATE
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-09-28
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.298 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVQ
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL BOUND TO COMPETITIVE ANTAGONIST TNP-ATP
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, SODIUM ION, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-10-05
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVR
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CRYSTAL STRUCTURE OF THE ATP-GATED HUMAN P2X3 ION CHANNEL BOUND TO COMPETITIVE ANTAGONIST A-317491
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-10-05
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVS
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ANOMALOUS MN2+ SIGNAL REVEALS A DIVALENT CATION-BINDING SITE IN THE HEAD DOMAIN OF THE ATP-GATED HUMAN P2X3 ION CHANNEL
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-09-28
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (4.025 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5SVT
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ANOMALOUS CS+ SIGNAL REVEALS THE SITE OF NA+ ION ENTRY TO THE CHANNEL PORE OF THE HUMAN P2X3 ION CHANNEL THROUGH THE EXTRACELLULAR FENESTRATIONS
Descriptor:P2X purinoceptor 3, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION, ...
Authors:Mansoor, S.E., Lu, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2016-08-07
Release date:2016-09-28
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.794 Å)
Cite:X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
5U4I
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STRUCTURAL BASIS OF CO-TRANSLATIONAL QUALITY CONTROL BY ARFA AND RF2 BOUND TO RIBOSOME
Descriptor:23S rRNA, 5S rRNA, 50S ribosomal protein L2, ...
Authors:Zeng, F., Chen, Y., Remis, J., Shekhar, M., Phillips, J.C., Tajkhorshid, E., Jin, H.
Deposit date:2016-12-04
Release date:2017-01-11
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
5U4J
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STRUCTURAL BASIS OF CO-TRANSLATIONAL QUALITY CONTROL BY ARFA AND RF2 BOUND TO RIBOSOME
Descriptor:16S rRNA, 23S rRNA, 30S ribosomal protein S3, ...
Authors:Zeng, F., Chen, Y., Remis, J., Shekhar, M., Phillips, J.C., Tajkhorshid, E., Jin, H.
Deposit date:2016-12-04
Release date:2017-01-11
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome.
Nature, 541, 2017
5VOT
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STRUCTURE OF A PROTEIN COMPLEX
Descriptor:Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Chen, S., Zhao, Y., Wang, Y.S., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
5VOU
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STRUCTURE OF A PROTEIN COMPLEX
Descriptor:Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Chen, S., Zhao, Y., Wang, Y.S., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
5VOV
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STRUCTURE OF A PROTEIN COMPLEX
Descriptor:Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Zhao, Y., Chen, S., Wang, Y.S., Shekhar, M., Tajkhorshid, E., Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
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