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3ZQJ
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BU of 3zqj by Molmil
Mycobacterium tuberculosis UvrA
Descriptor: UVRABC SYSTEM PROTEIN A, ZINC ION
Authors:Rossi, F, Khanduja, J.S, Bortoluzzi, A, Houghton, J, Sander, P, Guthlein, C, Davis, E.O, Springer, B, Bottger, E.C, Relini, A, Penco, A, Muniyappa, K, Rizzi, M.
Deposit date:2011-06-09
Release date:2011-06-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The Biological and Structural Characterization of Mycobacterium Tuberculosis Uvra Provides Novel Insights Into its Mechanism of Action
Nucleic Acids Res., 39, 2011
2XH1
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BU of 2xh1 by Molmil
Crystal structure of human KAT II-inhibitor complex
Descriptor: (3S)-10-(4-AMINOPIPERAZIN-1-YL)-9-FLUORO-7-HYDROXY-3-METHYL-2,3-DIHYDRO-8H-[1,4]OXAZINO[2,3,4-IJ]QUINOLINE-6-CARBOXYLATE, GLYCEROL, IODIDE ION, ...
Authors:Rossi, F, Casazza, V, Garavaglia, S, Sathyasaikumar, K.V, Schwarcz, R, Kojima, S.I, Okuwaki, K, Ono, S.I, Kajii, Y, Rizzi, M.
Deposit date:2010-06-08
Release date:2010-07-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure-Based Selective Targeting of the Pyridoxal 5'-Phsosphate Dependent Enzyme Kynurenine Aminotransferase II for Cognitive Enhancement
J.Med.Chem., 53, 2010
2VGZ
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BU of 2vgz by Molmil
CRYSTAL STRUCTURE OF HUMAN KYNURENINE AMINOTRANSFERASE II
Descriptor: IODIDE ION, KYNURENINE/ALPHA-AMINOADIPATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Rossi, F, Garavaglia, S, Montalbano, V, Walsh, M.A, Rizzi, M.
Deposit date:2007-11-16
Release date:2007-12-04
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Human Kynurenine Aminotransferase II, a Drug Target for the Treatment of Schizophrenia.
J.Biol.Chem., 283, 2008
2CH2
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BU of 2ch2 by Molmil
Structure of the Anopheles gambiae 3-hydroxykynurenine transaminase in complex with inhibitor
Descriptor: 3-HYDROXYKYNURENINE TRANSAMINASE, 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID, PYRIDOXAL-5'-PHOSPHATE
Authors:Rossi, F, Garavaglia, S, Giovenzana, G.B, Arca, B, Li, J, Rizzi, M.
Deposit date:2006-03-10
Release date:2006-03-28
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of the Anopheles Gambiae 3-Hydroxykynurenine Transaminase
Proc.Natl.Acad.Sci.USA, 103, 2006
2CH1
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BU of 2ch1 by Molmil
Structure of Anopheles gambiae 3-hydroxykynurenine transaminase
Descriptor: 3-HYDROXYKYNURENINE TRANSAMINASE, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE
Authors:Rossi, F, Garavaglia, S, Giovenzana, G.B, Arca, B, Li, J, Rizzi, M.
Deposit date:2006-03-10
Release date:2006-03-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Anopheles Gambiae 3-Hydroxykynurenine Transaminase
Proc.Natl.Acad.Sci.USA, 103, 2006
1W7L
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BU of 1w7l by Molmil
Crystal structure of human kynurenine aminotransferase I
Descriptor: KYNURENINE--OXOGLUTARATE TRANSAMINASE I, PYRIDOXAL-5'-PHOSPHATE
Authors:Rossi, F, Han, Q, Li, J, Li, J, Rizzi, M.
Deposit date:2004-09-06
Release date:2004-09-08
Last modified:2015-12-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Human Kynurenine Aminotransferase I
J.Biol.Chem., 279, 2004
1W7N
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BU of 1w7n by Molmil
Crystal structure of human kynurenine aminotransferase I in PMP form
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, KYNURENINE--OXOGLUTARATE TRANSAMINASE I
Authors:Rossi, F, Han, Q, Li, J, Li, J, Rizzi, M.
Deposit date:2004-09-06
Release date:2004-09-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of Human Kynurenine Aminotransferase I
J.Biol.Chem., 279, 2004
1W7M
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BU of 1w7m by Molmil
Crystal structure of human kynurenine aminotransferase I in complex with L-Phe
Descriptor: KYNURENINE--OXOGLUTARATE TRANSAMINASE I, PHENYLALANINE, PYRIDOXAL-5'-PHOSPHATE
Authors:Rossi, F, Han, Q, Li, J, Li, J, Rizzi, M.
Deposit date:2004-09-06
Release date:2004-09-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Human Kynurenine Aminotransferase I
J.Biol.Chem., 279, 2004
6GA0
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BU of 6ga0 by Molmil
Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with SNAP-Vista Green
Descriptor: 5-[(4-methylphenyl)methylcarbamoyl]-2-(6-oxidanyl-3-oxidanylidene-4~{H}-xanthen-9-yl)benzoic acid, Methylated-DNA--protein-cysteine methyltransferase, SULFATE ION
Authors:Miggiano, R, Rossi, F, Rizzi, M.
Deposit date:2018-04-11
Release date:2018-05-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe.
Biochem. Biophys. Res. Commun., 500, 2018
5LLQ
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BU of 5llq by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase C119F variant
Descriptor: GLYCEROL, Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R, Rossi, F, Rizzi, M.
Deposit date:2016-07-28
Release date:2016-11-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase.
Biochim.Biophys.Acta, 1861, 2016
7R0S
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BU of 7r0s by Molmil
Structure of a cytosolic sulfotransferase of Anopheles gambiae (AGAP001425) in complex with vanillin
Descriptor: 4-hydroxy-3-methoxybenzaldehyde, AGAP001425-PA, CHLORIDE ION, ...
Authors:Esposito Verza, A, Miggiano, R, Rizzi, R, Rossi, F.
Deposit date:2022-02-02
Release date:2022-08-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues.
Curr Res Struct Biol, 4, 2022
7R0O
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BU of 7r0o by Molmil
Structure of a cytosolic sulfotransferase of Anopheles gambiae (AGAP001425).
Descriptor: AGAP001425-PA, CHLORIDE ION, GLYCEROL
Authors:Esposito Verza, A, Miggiano, R, Rizzi, R, Rossi, F.
Deposit date:2022-02-02
Release date:2022-08-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues.
Curr Res Struct Biol, 4, 2022
7R0U
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BU of 7r0u by Molmil
Structure of a cytosolic sulfotransferase of Anopheles gambiae (AGAP001425) in complex with 3'-phosphoadenosine 5-phosphate and vanillin.
Descriptor: 4-hydroxy-3-methoxybenzaldehyde, ADENOSINE-3'-5'-DIPHOSPHATE, AGAP001425-PA, ...
Authors:Esposito Verza, A, Miggiano, R, Rizzi, R, Rossi, F.
Deposit date:2022-02-02
Release date:2022-08-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues.
Curr Res Struct Biol, 4, 2022
4ZYE
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BU of 4zye by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase
Descriptor: GLYCEROL, Methylated-DNA--protein-cysteine methyltransferase, NITRATE ION
Authors:Miggiano, R, Rossi, F, Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4ZYD
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BU of 4zyd by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase in complex with modified DNA
Descriptor: DNA (5'-D(*GP*CP*CP*AP*TP*GP*(6OG)P*CP*TP*AP*GP*TP*A)-3'), DNA (5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3'), Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R, Rossi, F, Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.682 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4ZYH
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BU of 4zyh by Molmil
Crystal structure of Sulfolobus solfataricus O6-methylguanine methyltransferase C119L variant
Descriptor: Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R, Rossi, F, Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4ZYG
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BU of 4zyg by Molmil
Crystal structure of methylated Sulfolobus solfataricus O6-methylguanine methyltransferase
Descriptor: Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R, Rossi, F, Rizzi, M.
Deposit date:2015-05-21
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein.
Nucleic Acids Res., 43, 2015
4WXD
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BU of 4wxd by Molmil
Crystal structure of Mycobacterium tuberculosis OGT-R37K
Descriptor: GLYCEROL, Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R, Rossi, F, Garavaglia, S, Rizzi, M.
Deposit date:2014-11-13
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA.
Biochem.J., 473, 2016
4WX9
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BU of 4wx9 by Molmil
Crystal structure of Mycobacterium tuberculosis OGT in complex with DNA
Descriptor: DNA (5'-D(*GP*CP*CP*AP*TP*GP*(E1X)P*CP*TP*AP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3'), GLYCEROL, ...
Authors:Miggiano, R, Rossi, F, Garavaglia, S, Rizzi, M.
Deposit date:2014-11-13
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA.
Biochem.J., 473, 2016
4WXC
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BU of 4wxc by Molmil
Crystal structure of Mycobacterium tuberculosis OGT-Y139F
Descriptor: 1,2-ETHANEDIOL, Methylated-DNA--protein-cysteine methyltransferase
Authors:Miggiano, R, Rossi, F, Garavaglia, S, Rizzi, M.
Deposit date:2014-11-13
Release date:2015-11-04
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA.
Biochem.J., 473, 2016
4BHC
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BU of 4bhc by Molmil
CRYSTAL STRUCTURE OF THE M. TUBERCULOSIS O6-METHYLGUANINE METHYLTRANSFERASE R37L VARIANT
Descriptor: METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE
Authors:Miggiano, R, Casazza, V, Garavaglia, S, Ciaramella, M, Perugino, G, Rizzi, M, Rossi, F.
Deposit date:2013-04-02
Release date:2013-04-17
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Biochemical and Structural Studies on the M. Tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants.
J.Bacteriol., 195, 2013
4BHB
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BU of 4bhb by Molmil
Crystal structure of Mycobacterium tuberculosis O6-METHYLGUANINE METHYLTRANSFERASE
Descriptor: GLYCEROL, METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE
Authors:Miggiano, R, Casazza, V, Garavaglia, S, Ciaramella, M, Perugino, G, Rizzii, M, Rossi, F.
Deposit date:2013-04-02
Release date:2013-04-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biochemical and Structural Studies of the Mycobacterium Tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants.
J.Bacteriol., 195, 2013
6XXY
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BU of 6xxy by Molmil
Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase in complex with O-isobutenyl oxalylhydroxamate.
Descriptor: 2-(2-methylprop-2-enoxyamino)-2-oxidanylidene-ethanoic acid, 3-isopropylmalate dehydrogenase, MAGNESIUM ION, ...
Authors:Miggiano, R, Rossi, F, Martignon, S, Rizzi, M.
Deposit date:2020-01-28
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate.
Biochem.Biophys.Res.Commun., 524, 2020
6EKH
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BU of 6ekh by Molmil
Crystal structure of activated CheY from Methanoccocus maripaludis
Descriptor: BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein CheY, MAGNESIUM ION
Authors:Altegoer, F, Bange, G.
Deposit date:2017-09-26
Release date:2018-01-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.654 Å)
Cite:Structure and function of the archaeal response regulator CheY.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EKG
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BU of 6ekg by Molmil
Crystal structure of an archaeal CheY from Methanoccocus maripaludis
Descriptor: Chemotaxis protein CheY, MAGNESIUM ION
Authors:Altegoer, F, Bange, G.
Deposit date:2017-09-26
Release date:2018-01-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structure and function of the archaeal response regulator CheY.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

 

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