2VGZ

CRYSTAL STRUCTURE OF HUMAN KYNURENINE AMINOTRANSFERASE II

Summary for 2VGZ

Entry DOI	10.2210/pdb2vgz/pdb
Descriptor	KYNURENINE/ALPHA-AMINOADIPATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, IODIDE ION, ... (4 entities in total)
Functional Keywords	multifunctional enzyme, transit peptide, aminotransferase, pyridoxal phosphate, plp enzyme, kynurenine, transferase, mitochondrion
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Mitochondrion : Q8N5Z0
Total number of polymer chains	2
Total formula weight	95906.59
Authors	Rossi, F.,Garavaglia, S.,Montalbano, V.,Walsh, M.A.,Rizzi, M. (deposition date: 2007-11-16, release date: 2007-12-04, Last modification date: 2015-12-09)
Primary citation	Rossi, F.,Garavaglia, S.,Montalbano, V.,Walsh, M.A.,Rizzi, M. Crystal Structure of Human Kynurenine Aminotransferase II, a Drug Target for the Treatment of Schizophrenia. J.Biol.Chem., 283:3559-, 2008 Cited by PubMed: 18056996 DOI: 10.1074/JBC.M707925200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation