4WX9
Crystal structure of Mycobacterium tuberculosis OGT in complex with DNA
Summary for 4WX9
Entry DOI | 10.2210/pdb4wx9/pdb |
Descriptor | DNA (5'-D(*GP*CP*CP*AP*TP*GP*(E1X)P*CP*TP*AP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3'), Methylated-DNA--protein-cysteine methyltransferase, ... (5 entities in total) |
Functional Keywords | direct dna damage reversal, alkylated dna-protein alkyltransferase, protein-dna complex, transferase |
Biological source | Mycobacterium tuberculosis More |
Cellular location | Cytoplasm : P9WJW5 |
Total number of polymer chains | 5 |
Total formula weight | 61656.80 |
Authors | Miggiano, R.,Rossi, F.,Garavaglia, S.,Rizzi, M. (deposition date: 2014-11-13, release date: 2015-11-04, Last modification date: 2024-01-10) |
Primary citation | Miggiano, R.,Perugino, G.,Ciaramella, M.,Serpe, M.,Rejman, D.,Pav, O.,Pohl, R.,Garavaglia, S.,Lahiri, S.,Rizzi, M.,Rossi, F. Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA. Biochem.J., 473:123-133, 2016 Cited by PubMed: 26512127DOI: 10.1042/BJ20150833 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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