4WX9
Crystal structure of Mycobacterium tuberculosis OGT in complex with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | DNA (5'-D(*GP*CP*CP*AP*TP*GP*(E1X)P*CP*TP*AP*GP*TP*A)-3') | polymer | 13 | 4020.6 | 1 | synthetic construct | ||
| 2 | B (E) | DNA (5'-D(P*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3') | polymer | 13 | 3951.6 | 1 | synthetic construct | ||
| 3 | C, D, E (A, B, C) | Methylated-DNA--protein-cysteine methyltransferase | polymer | 165 | 17864.2 | 3 | UniProt (P9WJW5) Pfam (PF02870) Pfam (PF01035) | Mycobacterium tuberculosis | 6-O-methylguanine-DNA methyltransferase,MGMT,O-6-methylguanine-DNA-alkyltransferase |
| 4 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | G, H, I (A, B, C) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 165 (UniProt: P9WJW5)
| PDB | External Database | Details |
|---|---|---|
| Val 2 | Ile 2 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 61564.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 61656.8 |
