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2CKW
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THE 2.3 A RESOLUTION STRUCTURE OF THE SAPPORO VIRUS RNA DEPENDANT RNA POLYMERASE.
Descriptor:RNA-DIRECTED RNA POLYMERASE
Authors:Fullerton, S.W.B., Tucker, P.A., Rohayem, J., Coutard, B., Gebhardt, J., Gorbalenya, A., Canard, B.
Deposit date:2006-04-24
Release date:2006-11-29
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Characterization of Sapovirus RNA-Dependent RNA Polymerase.
J.Virol., 81, 2007
2UUT
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THE 2.4 ANGSTROM RESOLUTION STRUCTURE OF THE D346G MUTANT OF THE SAPPORO VIRUS RDRP POLYMERASE
Descriptor:RNA-DIRECTED RNA POLYMERASE
Authors:Fullerton, S.W.B., Robel, I., Schuldt, L., Gebhardt, J., Tucker, P., Rohayem, J.
Deposit date:2007-03-07
Release date:2007-05-01
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The 2.4 Angstrom Resolution Structure of the D346G Mutant of the Sapporo Virus Rdrp Polymerase
To be Published
2UUW
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2.75 ANGSTROM STRUCTURE OF THE D347G D348G MUTANT STRUCTURE OF SAPPORO VIRUS RDRP POLYMERASE
Descriptor:RNA-DIRECTED RNA POLYMERASE
Authors:Fullerton, S., Robel, I., Schuldt, L., Gebhardt, J., Tucker, P., Rohayem, J.
Deposit date:2007-03-07
Release date:2007-05-01
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:The 2.76 Angstrom Resolution Structure of the D347G D348G Mutant Structure of Sapporo Virus Rdrp Polymerase
To be Published
2W5E
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STRUCTURAL AND BIOCHEMICAL ANALYSIS OF HUMAN PATHOGENIC ASTROVIRUS SERINE PROTEASE AT 2.0 ANGSTROM RESOLUTION
Descriptor:PUTATIVE SERINE PROTEASE, CADMIUM ION, CHLORIDE ION
Authors:Speroni, S., Rohayem, J., Nenci, S., Bonivento, D., Robel, I., Barthel, J., Coutard, B., Canard, B., Mattevi, A.
Deposit date:2008-12-10
Release date:2009-03-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Biochemical Analysis of Human Pathogenic Astrovirus Serine Protease at 2.0 A Resolution.
J.Mol.Biol., 387, 2009
2WK4
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DIMERIC STRUCTURE OF D347G D348G MUTANT OF THE SAPPOROVIRUS RNA DEPENDENT RNA POLYMERASE
Descriptor:PROTEASE-POLYMERASE P70, GLYCEROL
Authors:Fullerton, S.W.B., Robel, I., Schuldt, L., Gebhardt, J., Tucker, P.A., Rohayem, J.
Deposit date:2009-06-05
Release date:2010-09-01
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Dimeric Structure of D347G D348G Mutant of the Sapporovirus Sapporovirus RNA Dependent RNA Polymerase
To be Published
2B43
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CRYSTAL STRUCTURE OF THE NORWALK VIRUS RNA DEPENDENT RNA POLYMERASE FROM STRAIN HU/NLV/DRESDEN174/1997/GE
Descriptor:non-structural polyprotein
Authors:Hogbom, M., Rohayem, J., Unge, T., Jones, T.A.
Deposit date:2005-09-22
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Norwalk virus RNA dependent RNA polymerase from strain Hu/NLV/Dresden174/1997/GE
To be Published
3UPF
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CRYSTAL STRUCTURE OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE BOUND TO NF023
Descriptor:RNA-dependent RNA polymerase, 8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid, SULFATE ION
Authors:Milani, M., Mastrangelo, E., Bolognesi, M.
Deposit date:2011-11-18
Release date:2012-05-02
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases.
J.Mol.Biol., 419, 2012
3UQS
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CRYSTAL STRUCTURES OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE
Descriptor:RNA-dependent RNA polymerase, SULFATE ION
Authors:Milani, M., Mastrangelo, E., Bolognesi, M.
Deposit date:2011-11-21
Release date:2012-05-02
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases.
J.Mol.Biol., 419, 2012
3UR0
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CRYSTAL STRUCTURES OF MURINE NOROVIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH SURAMIN
Descriptor:RNA-dependent RNA polymerase, SULFATE ION, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID
Authors:Milani, M., Mastrangelo, E., Bolognesi, M.
Deposit date:2011-11-21
Release date:2012-05-02
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases.
J.Mol.Biol., 419, 2012
4LQ3
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CRYSTAL STRUCTURE OF HUMAN NOROVIRUS RNA-DEPENDENT RNA-POLYMERASE BOUND TO THE INHIBITOR PPNDS
Descriptor:RNA-dependent RNA-polymerase, 5'-R(P*GP*G)-3', 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, ...
Authors:Milani, M., Tarantino, D., Mastrangelo, E., Croci, R.
Deposit date:2013-07-17
Release date:2014-02-12
Last modified:2014-11-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase.
Antiviral Res., 102, 2014
4LQ9
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CRYSTAL STRUCTURE OF HUMAN NOROVIRUS RNA-DEPENDENT RNA-POLYMERASE IN COMPLEX WITH NAF2
Descriptor:RNA-dependent RNA-polymerase, naphthalene-1,5-disulfonic acid, MAGNESIUM ION
Authors:Milani, M., Tarantino, D., Mastrangelo, E., Croci, R.
Deposit date:2013-07-17
Release date:2014-02-12
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase.
Antiviral Res., 102, 2014
4NRT
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HUMAN NOROVIRUS POLYMERASE BOUND TO COMPOUND 6 (SURAMIN DERIVATIVE)
Descriptor:hNV-RdRp, 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid
Authors:Croci, R., Pezzullo, M., Tarantino, D., Mastrangelo, E., Milani, M., Bolognesi, M.
Deposit date:2013-11-27
Release date:2014-10-15
Method:X-RAY DIFFRACTION (2.022 Å)
Cite:Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.
Plos One, 9, 2014
4NRU
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MURINE NOROVIRUS RNA-DEPENDENT-RNA-POLYMERASE IN COMPLEX WITH COMPOUND 6, A SURAMIN DERIVATIVE
Descriptor:RNA dependent RNA polymerase, 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid, MAGNESIUM ION
Authors:Milani, M., Croci, R., Pezzullo, M., Tarantino, D., Mastrangelo, E., Bolognesi, M.
Deposit date:2013-11-27
Release date:2014-10-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.
Plos One, 9, 2014
4O4R
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MURINE NOROVIRUS RDRP IN COMPLEX WITH PPNDS
Descriptor:RNA-dependent-RNA-polymerase, 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, SULFATE ION
Authors:Croci, R., Tarantino, D., Milani, M., Pezzullo, M., Bolognesi, M., Mastrangelo, E.
Deposit date:2013-12-19
Release date:2014-11-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:PPNDS inhibits murine Norovirus RNA-dependent RNA-polymerase mimicking two RNA stacking bases.
Febs Lett., 588, 2014