Author results

1D9K
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CRYSTAL STRUCTURE OF COMPLEX BETWEEN D10 TCR AND PMHC I-AK/CA
分子名称:T-CELL RECEPTOR D10 (ALPHA CHAIN), T-CELL RECEPTOR D10 (BETA CHAIN), MHC I-AK A CHAIN (ALPHA CHAIN), ...
著者Reinherz, E.L., Tan, K., Tang, L., Kern, P., Liu, J.-H., Xiong, Y., Hussey, R.E., Smolyar, A., Hare, B., Zhang, R., Joachimiak, A., Chang, H.-C., Wagner, G., Wang, J.-H.
登録日1999-10-28
公開日1999-12-15
最終更新日2017-02-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The crystal structure of a T cell receptor in complex with peptide and MHC class II.
Science, 286, 1999
1JBJ
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CD3 EPSILON AND GAMMA ECTODOMAIN FRAGMENT COMPLEX IN SINGLE-CHAIN CONSTRUCT
分子名称:CD3 Epsilon and gamma Ectodomain Fragment Complex
著者Sun, Z.-Y.J., Kim, K.S., Wagner, G., Reinherz, E.L.
登録日2001-06-05
公開日2001-12-05
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Mechanisms contributing to T cell receptor signaling and assembly revealed by the solution structure of an ectodomain fragment of the CD3 epsilon gamma heterodimer.
Cell(Cambridge,Mass.), 105, 2001
1NFD
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AN ALPHA-BETA T CELL RECEPTOR (TCR) HETERODIMER IN COMPLEX WITH AN ANTI-TCR FAB FRAGMENT DERIVED FROM A MITOGENIC ANTIBODY
分子名称:N15 ALPHA-BETA T-CELL RECEPTOR, H57 FAB, N-ACETYL-D-GLUCOSAMINE, ...
著者Wang, J.-H., Lim, K., Smolyar, A., Teng, M.-K., Sacchittini, J., Reinherz, E.L.
登録日1997-08-04
公開日1998-01-28
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody.
EMBO J., 17, 1998
1QA9
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STRUCTURE OF A HETEROPHILIC ADHESION COMPLEX BETWEEN THE HUMAN CD2 AND CD58(LFA-3) COUNTER-RECEPTORS
分子名称:HUMAN CD2 PROTEIN, HUMAN CD58 PROTEIN
著者Wang, J.-H., Smolyar, A., Tan, K., Liu, J.-H., Kim, M., Sun, Z.J., Wagner, G., Reinherz, E.L.
登録日1999-04-13
公開日1999-04-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors.
Cell(Cambridge,Mass.), 97, 1999
1BQH
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MURINE CD8AA ECTODOMAIN FRAGMENT IN COMPLEX WITH H-2KB/VSV8
分子名称:PROTEIN (H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN), PROTEIN (BETA-2-MICROGLOBULIN ), PROTEIN (VSV8), ...
著者Wang, J.H., Reinherz, E.L., Kern, P.S., Chang, H.C.
登録日1998-08-16
公開日1998-08-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb.
Immunity, 9, 1998
1BWM
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A SINGLE-CHAIN T CELL RECEPTOR
分子名称:PROTEIN (ALPHA-BETA T CELL RECEPTOR (TCR) (D10))
著者Hare, B.J., Wyss, D.F., Reinherz, E.L., Wagner, G.
登録日1998-09-23
公開日1999-07-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor.
Nat.Struct.Biol., 6, 1999
1CI5
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GLYCAN-FREE MUTANT ADHESION DOMAIN OF HUMAN CD58 (LFA-3)
分子名称:PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58))
著者Sun, Z.Y.J., Dotsch, V., Kim, M., Li, J., Reinherz, E.L., Wagner, G.
登録日1999-04-07
公開日1999-06-22
最終更新日2018-03-14
実験手法SOLUTION NMR
主引用文献Functional glycan-free adhesion domain of human cell surface receptor CD58: design, production and NMR studies.
EMBO J., 18, 1999
1GYF
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GYF DOMAIN FROM HUMAN CD2BP2 PROTEIN
分子名称:PROTEIN (CYTOPLASMIC DOMAIN BINDING PROTEIN (CD2BP2))
著者Freund, C., Doetsch, V., Nishizawa, K., Reinherz, E.L., Wagner, G.
登録日1999-04-30
公開日2000-01-05
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The GYF domain is a novel structural fold that is involved in lymphoid signaling through proline-rich sequences.
Nat.Struct.Biol., 6, 1999
1JL4
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CRYSTAL STRUCTURE OF THE HUMAN CD4 N-TERMINAL TWO DOMAIN FRAGMENT COMPLEXED TO A CLASS II MHC MOLECULE
分子名称:H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-K ALPHA CHAIN, A-K BETA CHAIN, ...
著者Wang, J.-H., Meijers, R., Reinherz, E.L.
登録日2001-07-15
公開日2001-09-19
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule.
Proc.Natl.Acad.Sci.USA, 98, 2001
1L2Z
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CD2BP2-GYF DOMAIN IN COMPLEX WITH PROLINE-RICH CD2 TAIL SEGMENT PEPTIDE
分子名称:CD2 ANTIGEN (CYTOPLASMIC TAIL)-BINDING PROTEIN 2, T-CELL SURFACE ANTIGEN CD2
著者Freund, C., Kuhne, R., Yang, H., Park, S., Reinherz, E.L., Wagner, G.
登録日2002-02-26
公開日2002-11-20
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules
Embo J., 21, 2002
1NEZ
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THE CRYSTAL STRUCTURE OF A TL/CD8AA COMPLEX AT 2.1A RESOLUTION:IMPLICATIONS FOR MEMORY T CELL GENERATION, CO-RECEPTOR PREFERENCE AND AFFINITY
分子名称:H-2 class I histocompatibility antigen, TLA(C) alpha chain, Beta-2-microglobulin, ...
著者Liu, Y., Xiong, Y., Naidenko, O.V., Liu, J.H., Zhang, R., Joachimiak, A., Kronenberg, M., Cheroutre, H., Reinherz, E.L., Wang, J.H.
登録日2002-12-12
公開日2003-04-08
最終更新日2013-09-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Crystal Structure of a TL/CD8alphaalpha Complex at 2.1 A resolution: Implications for modulation of T cell activation and memory
Immunity, 18, 2003
1OSZ
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MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND AN (L4V) MUTANT OF THE VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
分子名称:MHC CLASS I H-2KB HEAVY CHAIN, BETA-2 MICROGLOBULIN, VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
著者Ghendler, Y., Teng, M.-K., Liu, J.-H., Witte, T., Liu, J., Kim, K.S., Kern, P., Chang, H.-C., Wang, J.-H., Reinherz, E.L.
登録日1998-06-18
公開日1999-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Differential thymic selection outcomes stimulated by focal structural alteration in peptide/major histocompatibility complex ligands.
Proc.Natl.Acad.Sci.USA, 95, 1998
1WBX
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CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 DB AND KB MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE
分子名称:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, BETA-2MICROGLOBULIN, ...
著者Meijers, R., Lai, C., Yang, Y., Liu, J., Zhong, W., Wang, J., Reinherz, E.L.
登録日2004-11-05
公開日2005-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance
J.Mol.Biol., 345, 2005
1WBY
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CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 DB AND KB MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE
分子名称:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, BETA-2MICROGLOBULIN, ...
著者Meijers, R., Lai, C., Yang, Y., Liu, J., Zhong, W., Wang, J., Reinherz, E.L.
登録日2004-11-05
公開日2005-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance
J.Mol.Biol., 345, 2005
1WBZ
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CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 DB AND KB MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE
分子名称:H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN PRECURSOR, BETA-2MICROGLOBULIN, ...
著者Meijers, R., Lai, C., Yang, Y., Liu, J., Zhong, W., Wang, J., Reinherz, E.L.
登録日2004-11-05
公開日2005-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance
J.Mol.Biol., 345, 2005
1XMW
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CD3 EPSILON AND DELTA ECTODOMAIN FRAGMENT COMPLEX IN SINGLE-CHAIN CONSTRUCT
分子名称:Chimeric CD3 mouse Epsilon and sheep Delta Ectodomain Fragment Complex
著者Sun, Z.-Y.J., Kim, S.T., Kim, I.C., Fahmy, A., Reinherz, E.L., Wagner, G.
登録日2004-10-04
公開日2004-11-30
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling.
Proc.Natl.Acad.Sci.Usa, 101, 2004
2ATP
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CRYSTAL STRUCTURE OF A CD8AB HETERODIMER
分子名称:T-cell surface glycoprotein CD8 alpha chain, artifact linker, T-cell surface glycoprotein CD8 beta chain, ...
著者Chang, H.C., Tan, K., Ouyang, J., Parisini, E., Liu, J.H., Le, Y., Wang, X., Reinherz, E.L., Wang, J.H.
登録日2005-08-25
公開日2005-12-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Mutational Analyses of a CD8alphabeta Heterodimer and Comparison with the CD8alphaalpha Homodimer.
Immunity, 23, 2005
2JXB
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STRUCTURE OF CD3EPSILON-NCK2 FIRST SH3 DOMAIN COMPLEX
分子名称:T-cell surface glycoprotein CD3 epsilon chain, Cytoplasmic protein NCK2
著者Takeuchi, K., Yang, H., Ng, E., Park, S., Sun, Z.J., Reinherz, E.L., Wagner, G.
登録日2007-11-09
公開日2008-09-23
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity.
J.Mol.Biol., 380, 2008
2ME1
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HIV-1 GP41 CLADE B DOUBLE ALANINE MUTANT MEMBRANE PROXIMAL EXTERNAL REGION PEPTIDE IN DPC MICELLE
分子名称:Gp41
著者Sun, Z.J., Wagner, G., Reinherz, E.L., Kim, M., Song, L., Choi, J., Cheng, Y., Chowdhury, B., Bellot, G., Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2014-03-05
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME2
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HIV-1 GP41 CLADE C MEMBRANE PROXIMAL EXTERNAL REGION PEPTIDE IN DPC MICELLE
分子名称:Envelope glycoprotein gp160
著者Sun, Z.J., Wagner, G., Reinherz, E.L., Kim, M., Song, L., Choi, J., Cheng, Y., Chowdhury, B., Bellot, G., Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2014-03-05
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME3
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HIV-1 GP41 CLADE C MEMBRANE PROXIMAL EXTERNAL REGION PEPTIDE IN DPC MICELLE
分子名称:Envelope glycoprotein gp160
著者Sun, Z.J., Wagner, G., Reinherz, E.L., Kim, M., Song, L., Choi, J., Cheng, Y., Chowdhury, B., Bellot, G., Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2014-03-05
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2ME4
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HIV-1 GP41 CLADE C MEMBRANE PROXIMAL EXTERNAL REGION PEPTIDE IN DPC MICELLE
分子名称:Envelope glycoprotein gp160
著者Sun, Z.J., Wagner, G., Reinherz, E.L., Kim, M., Song, L., Choi, J., Cheng, Y., Chowdhury, B., Bellot, G., Shih, W.
登録日2013-09-20
公開日2013-10-09
最終更新日2014-03-05
実験手法SOLUTION NMR
主引用文献Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
2PV6
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HIV-1 GP41 MEMBRANE PROXIMAL ECTODOMAIN REGION PEPTIDE IN DPC MICELLE
分子名称:Envelope glycoprotein
著者Sun, Z.-Y.J., Oh, K.J., Kim, M., Reinherz, E.L., Wagner, G.
登録日2007-05-09
公開日2008-03-18
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane
Immunity, 28, 2008
6MF8
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TCR ALPHA TRANSMEMBRANE DOMAIN
分子名称:T-cell receptor alpha chain C region
著者Brazin, K.N., Reinherz, E.L.
登録日2018-09-10
公開日2018-12-12
実験手法SOLUTION NMR
主引用文献The T Cell Antigen Receptor alpha Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations.
Immunity, 49, 2018
1CDB
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STRUCTURE OF THE GLYCOSYLATED ADHESION DOMAIN OF HUMAN T LYMPHOCYTE GLYCOPROTEIN CD2
分子名称:CD2
著者Wyss, D.F., Withka, J.M., Recny, M.A., Wagner, G.
登録日1993-09-15
公開日1994-01-31
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of the glycosylated adhesion domain of human T lymphocyte glycoprotein CD2.
Structure, 1, 1993
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