5OGW
| Cryo-EM structure of jasplakinolide-stabilized malaria parasite F-actin at near-atomic resolution | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ... | Authors: | Pospich, S, Kumpula, E.-P, von der Ecken, J, Vahokoski, J, Kursula, I, Raunser, S. | Deposit date: | 2017-07-13 | Release date: | 2017-09-27 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5JLF
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6FHL
| Cryo-EM structure of F-actin in complex with ADP-Pi | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Merino, F, Pospich, S, Funk, J, Wagner, T, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | Deposit date: | 2018-01-15 | Release date: | 2018-06-13 | Last modified: | 2018-08-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM. Nat. Struct. Mol. Biol., 25, 2018
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7AHQ
| Cryo-EM structure of F-actin stabilized by trans-optoJASP-8 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Pospich, S, Raunser, S. | Deposit date: | 2020-09-25 | Release date: | 2021-01-27 | Last modified: | 2021-04-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States. Angew.Chem.Int.Ed.Engl., 60, 2021
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4UWA
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4UWE
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2OF5
| Oligomeric Death Domain complex | Descriptor: | Death domain-containing protein CRADD, Leucine-rich repeat and death domain-containing protein | Authors: | Park, H.H, Logette, E, Raunser, S, Cuenin, S, Walz, T, Tschopp, J, Wu, H. | Deposit date: | 2007-01-02 | Release date: | 2007-04-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex. Cell(Cambridge,Mass.), 128, 2007
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3J8A
| Structure of the F-actin-tropomyosin complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | von der Ecken, J, Mueller, M, Lehman, W, Manstein, J.M, Penczek, A.P, Raunser, S. | Deposit date: | 2014-10-08 | Release date: | 2014-12-10 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of the F-actin--tropomyosin complex. Nature, 519, 2015
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8CQ2
| Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, C16S, C20S, C870S, T1279C mutant | Descriptor: | TcdA1 | Authors: | Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S. | Deposit date: | 2023-03-03 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Kinetics of the syringe-like injection mechanism of Tc toxins to be published
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8CPZ
| Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, K1179W mutant | Descriptor: | TcdA1 | Authors: | Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S. | Deposit date: | 2023-03-03 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Kinetics of the syringe-like injection mechanism of Tc toxins to be published
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8CQ0
| Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, K567W K2008W mutant | Descriptor: | TcdA1 | Authors: | Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S. | Deposit date: | 2023-03-03 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Kinetics of the syringe-like injection mechanism of Tc toxins to be published
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5JLH
| Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 2, ... | Authors: | von der Ecken, J, Heissler, S.M, Pathan-Chhatbar, S, Manstein, D.J, Raunser, S. | Deposit date: | 2016-04-27 | Release date: | 2016-06-15 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution. Nature, 534, 2016
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9FJO
| Structure of the undecorated pointed end of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | Deposit date: | 2024-05-31 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly Nat Commun, 2024
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7B1G
| TRPC4 in complex with Calmodulin | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CALCIUM ION, Calmodulin-1, ... | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | Deposit date: | 2020-11-24 | Release date: | 2020-12-09 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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7B0J
| TRPC4 in LMNG detergent | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CALCIUM ION, Transient receptor potential cation channel subfamily c member 4a | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | Deposit date: | 2020-11-20 | Release date: | 2020-12-09 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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9FJY
| Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 2). | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | Deposit date: | 2024-05-31 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.79 Å) | Cite: | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly Nat Commun, 2024
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9FJM
| Cryo-EM structure of the phalloidin-bound pointed end of the actin filament. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | Deposit date: | 2024-05-31 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly Nat Commun, 2024
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7B05
| TRPC4 in complex with inhibitor GFB-8749 | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 4-[4-[[4,4-bis(fluoranyl)cyclohexyl]methyl]-3-oxidanylidene-piperazin-1-yl]-5-chloranyl-1~{H}-pyridazin-6-one, CALCIUM ION, ... | Authors: | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | Deposit date: | 2020-11-18 | Release date: | 2020-12-09 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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9FJU
| Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | Deposit date: | 2024-05-31 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly Nat Commun, 2024
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7QPG
| Human RZZ kinetochore corona complex. | Descriptor: | Centromere/kinetochore protein zw10 homolog, Kinetochore-associated protein 1, Protein zwilch homolog | Authors: | Raisch, T, Ciossani, G, d'Amico, E, Cmetowski, V, Carmignani, S, Maffini, S, Merino, F, Wohlgemuth, S, Vetter, I.R, Raunser, S, Musacchio, A. | Deposit date: | 2022-01-04 | Release date: | 2022-03-16 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores. Embo J., 41, 2022
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4NF9
| Structure of the Knl1/Nsl1 complex | Descriptor: | CHLORIDE ION, Kinetochore-associated protein NSL1 homolog, Protein CASC5 | Authors: | Petrovic, A, Mosalaganti, S, Keller, J, Mattiuzzo, M, Overlack, K, Wohlgemuth, S, Pasqualato, S, Raunser, S, Musacchio, A. | Deposit date: | 2013-10-31 | Release date: | 2014-03-19 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization. Mol.Cell, 53, 2014
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4NFA
| Structure of the C-terminal doamin of Knl1 | Descriptor: | CHLORIDE ION, GLYCEROL, Protein CASC5 | Authors: | Petrovic, A, Mosalaganti, S, Keller, J, Mattiuzzo, M, Overlack, K, Wohlgemuth, S, Pasqualato, S, Raunser, S, Musacchio, A. | Deposit date: | 2013-10-31 | Release date: | 2014-03-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization. Mol.Cell, 53, 2014
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8Q5H
| Human KMN network (outer kinetochore) | Descriptor: | Kinetochore protein Spc24, Kinetochore protein Spc25, Kinetochore scaffold 1, ... | Authors: | Raisch, T, Polley, S, Vetter, I, Musacchio, A, Raunser, S. | Deposit date: | 2023-08-09 | Release date: | 2024-02-14 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure of the human KMN complex and implications for regulation of its assembly. Nat.Struct.Mol.Biol., 31, 2024
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7Q5P
| Structure of VgrG1 from Pseudomonas protegens. | Descriptor: | Type VI secretion protein VgrG | Authors: | Guenther, P, Quentin, D, Ahmad, S, Sachar, K, Gatsogiannis, C, Whitney, J.C, Raunser, S. | Deposit date: | 2021-11-04 | Release date: | 2021-12-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of a bacterial Rhs effector exported by the type VI secretion system. Plos Pathog., 18, 2022
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7Q97
| Structure of the bacterial type VI secretion system effector RhsA. | Descriptor: | Rhs family protein | Authors: | Guenther, P, Quentin, D, Ahmad, S, Sachar, K, Gatsogiannis, C, Whitney, J.C, Raunser, S. | Deposit date: | 2021-11-12 | Release date: | 2021-12-22 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of a bacterial Rhs effector exported by the type VI secretion system. Plos Pathog., 18, 2022
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