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5AAW
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STRUCTURE OF A REDESIGNED CROSS-REACTIVE ANTIBODY TO DENGUE VIRUS WITH INCREASED IN VIVO POTENCY
Descriptor:SCFV513, DENGUE SEROTYPE 4 ENVELOPE PROTEIN DOMAIN 3
Authors:Wong, Y., Robinson, L., Lescar, J., Sasisekharan, R.
Deposit date:2015-07-30
Release date:2015-09-30
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Structure-Guided Design of an Anti-Dengue Antibody Directed to a Non-Immunodominant Epitope.
Cell(Cambridge,Mass.), 162, 2015
5AAM
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STRUCTURE OF A REDESIGNED CROSS-REACTIVE ANTIBODY TO DENGUE VIRUS WITH INCREASED IN VIVO POTENCY
Descriptor:SCFV513, ENVELOPE PROTEIN
Authors:Wong, Y.H., Robinson, L.N., Lescar, J., Sasisekharan, R.
Deposit date:2015-07-27
Release date:2015-08-05
Last modified:2015-08-19
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure-Guided Design of an Anti-Dengue Antibody Directed to a Non-Immunodominant Epitope.
Cell(Cambridge,Mass.), 162, 2015
4M4K
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CRYSTAL STRUCTURE OF THE DROSPHILA BETA,14GALACTOSYLTRANSFERASE 7 MUTANT D211N COMPLEX WITH MANGANESE, UDP-GAL AND XYLOBIOSE
Descriptor:Beta-4-galactosyltransferase 7, MANGANESE (II) ION, GALACTOSE-URIDINE-5'-DIPHOSPHATE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-08-07
Release date:2013-09-25
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
4LW3
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CRYSTAL STRUCTURE OF THE DROSOPHILA BETA1,4GALACTOSYLTRANSFERASE7 CATALYTIC DOMAIN D211N SINGLE MUTANT ENZYME COMPLEX WITH MANGANESE AND UDP-GALACTOSE
Descriptor:Beta-4-galactosyltransferase 7, MANGANESE (II) ION, GALACTOSE-URIDINE-5'-DIPHOSPHATE
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-07-26
Release date:2013-09-25
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
4LW6
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF DROSOPHILA BETA1,4GALACTOSYLTRANSFERASE 7 COMPLEX WITH XYLOBIOSE
Descriptor:Beta-4-galactosyltransferase 7, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
Authors:Qasba, P.K., Ramakrishnan, B.
Deposit date:2013-07-26
Release date:2013-09-25
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
4L41
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HUMAN LACTOSE SYNTHASE: A 2:1 COMPLEX BETWEEN HUMAN ALPHA-LACTALBUMIN AND HUMAN BETA1,4-GALACTOSYLTRANSFERASE
Descriptor:Alpha-lactalbumin, Beta-1,4-galactosyltransferase 1, CALCIUM ION, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-06-07
Release date:2013-10-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Human Lactose Synthase forms a Novel 1:2 Complex between beta1,4Galactosyltransferase 1 and alpha-Lactalbumin Proteins
To be Published
4KRV
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF BOVINE BETA1,4-GALACTOSYLTRANSFERASE MUTANT M344H-GALT1 COMPLEX WITH 6-SULFO-GLCNAC
Descriptor:Beta-1,4-galactosyltransferase 1, MANGANESE (II) ION, 6-AMINOHEXYL-URIDINE-C1,5'-DIPHOSPHATE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-05-17
Release date:2013-08-28
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Investigations on beta 1,4-galactosyltransferase I using 6-sulfo-GlcNAc as an acceptor sugar substrate.
Glycoconj J, 30, 2013
4IRP
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN BETA1,4-GALACTOSYLTRANSFERASE-7 IN OPEN CONFORMATION WITH MANGANSES AND UDP
Descriptor:Beta-1,4-galactosyltransferase 7, URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Tsutsui, Y., Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-01-15
Release date:2013-09-25
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
4IRQ
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN BETA1,4GALACTOSYLTRANSFERASE 7 IN CLOSED CONFORMATION IN COMPLEX WITH MANGANESE AND UDP
Descriptor:Beta-1,4-galactosyltransferase 7, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
Authors:Tsutsui, Y., Ramakrishnan, B., Qasba, P.K.
Deposit date:2013-01-15
Release date:2013-09-25
Last modified:2015-02-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of beta-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding.
J.Biol.Chem., 288, 2013
4EE3
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH PENTASACCHARIDE
Descriptor:Beta-1,4-galactosyltransferase 1, BETA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EE4
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH TETRASACCHARIDE FROM LACTO-N-NEOHEXOSE
Descriptor:Beta-1,4-galactosyltransferase 1, BETA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EE5
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH TRISACCHARIDE FROM LACTO-N-NEOTETRAOSE
Descriptor:Beta-1,4-galactosyltransferase 1, BETA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EEA
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,6-GAL-BETA1,4-GLC-BETA
Descriptor:Beta-1,4-galactosyltransferase 1, BETA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EEG
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,6-GAL-BETA
Descriptor:Beta-1,4-galactosyltransferase 1, BETA-D-GALACTOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EEM
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,6-MAN-ALPHA-METHYL
Descriptor:Beta-1,4-galactosyltransferase 1, O1-METHYL-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
4EEO
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-1 (M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,6-GLCNAC-ALPHA-BENZYL
Descriptor:Beta-1,4-galactosyltransferase 1, benzyl 2-(acetylamino)-2-deoxy-alpha-D-glucopyranoside, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2012-03-28
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding of N-acetylglucosamine (GlcNAc) beta 1-6-branched oligosaccharide acceptors to beta 4-galactosyltransferase I reveals a new ligand binding mode.
J.Biol.Chem., 287, 2012
3LW6
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CRYSTAL STRUCTURE OF DROSOPHILA BETA1,4-GALACTOSYLTRANSFERASE-7
Descriptor:Beta-4-galactosyltransferase 7, URIDINE-5'-DIPHOSPHATE, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2010-02-23
Release date:2010-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure of the catalytic domain of Drosophila beta1,4-Galactosyltransferase-7.
J.Biol.Chem., 285, 2010
3EE5
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA1,4-GALACTOSYLTRANSFERASE-I (M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,3-GAL-BETA-NAPHTHALENEMETHANOL
Descriptor:Beta-1,4-galactosyltransferase 1, 6-AMINOHEXYL-URIDINE-C1,5'-DIPHOSPHATE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ramakrishnan, B., Qasba, P.K.
Deposit date:2008-09-04
Release date:2009-01-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Deoxygenated Disaccharide Analogs as Specific Inhibitors of {beta}1-4-Galactosyltransferase 1 and Selectin-mediated Tumor Metastasis
J.Biol.Chem., 284, 2009
2FY7
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE HUMAN BETA1,4-GALACTOSYLTRANSFERASE MUTANT M339H IN APO FORM
Descriptor:Beta-1,4-galactosyltransferase 1, TRIETHYLENE GLYCOL
Authors:Ramakrishnan, B., Ramasamy, V., Qasba, P.K.
Deposit date:2006-02-07
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway.
J.Mol.Biol., 357, 2006
2FYA
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE HUMAN BETA1, 4-GALACTOSYLTRANSFERASE MUTANT M339H COMPLEX WITH MANGANESE
Descriptor:Beta-1,4-galactosyltransferase 1, MANGANESE (II) ION, TRIETHYLENE GLYCOL
Authors:Ramakrishnan, B., Ramasamy, V., Qasba, P.K.
Deposit date:2006-02-07
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway.
J.Mol.Biol., 357, 2006
2FYB
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE HUMAN BETA1,4-GALACTOSYLTRANSFERASE MUTANT M339H IN COMPLEX WITH MN AND UDP-GALACTOSE IN OPEN CONFORMATION
Descriptor:Beta-1,4-galactosyltransferase 1, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE
Authors:Ramakrishnan, B., Ramasamy, V., Qasba, P.K.
Deposit date:2006-02-07
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway.
J.Mol.Biol., 357, 2006
2FYC
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF BOVINE BETA1,4-GALACTOSYLTRANSFERASE-I IN COMPLEX WITH ALPHA-LACTALBUMIN, CA AND UDP-GALACTOSE
Descriptor:Alpha-lactalbumin, beta-1,4-galactosyltransferase, CALCIUM ION, ...
Authors:Ramakrishnan, B., Ramasamy, V., Qasba, P.K.
Deposit date:2006-02-07
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway.
J.Mol.Biol., 357, 2006
2FYD
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CATALYTIC DOMAIN OF BOVINE BETA 1, 4-GALACTOSYLTRANSFERASE IN COMPLEX WITH ALPHA-LACTALBUMIN, GLUCOSE, MN, AND UDP-N-ACETYLGALACTOSAMINE
Descriptor:Alpha-lactalbumin, beta-1,4-galactosyltransferase, CALCIUM ION, ...
Authors:Ramakrishnan, B., Ramasamy, V., Qasba, P.K.
Deposit date:2006-02-07
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway.
J.Mol.Biol., 357, 2006
2AH9
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-I (M340H-B4GAL-T1) IN COMPLEX WITH CHITOTRIOSE
Descriptor:Beta-1,4-galactosyltransferase 1, TRIACETYLCHITOTRIOSE, MANGANESE (II) ION, ...
Authors:Ramasamy, V., Ramakrishnan, B., Boeggeman, E., Ratner, D.M., Seeberger, P.H., Qasba, P.K.
Deposit date:2005-07-27
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety
J.Mol.Biol., 353, 2005
2AGD
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CRYSTAL STRUCTURE OF HUMAN M340H-BETA-1,4-GALACTOSYLTRANSFERASE-I(M340H-B4GAL-T1) IN COMPLEX WITH GLCNAC-BETA1,4-MAN-ALPHA1,3-MAN-BETA-OR
Descriptor:Beta-1,4-galactosyltransferase 1, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Ramasamy, V., Ramakrishnan, B., Boeggeman, E., Ratner, D.M., Seeberger, P.H., Qasba, P.K.
Deposit date:2005-07-26
Release date:2005-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety
J.Mol.Biol., 353, 2005
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