Author results

1T3D
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CRYSTAL STRUCTURE OF SERINE ACETYLTRANSFERASE FROM E.COLI AT 2.2A
Descriptor:Serine acetyltransferase, CYSTEINE
Authors:Pye, V.E., Tingey, A.P., Robson, R.L., Moody, P.C.E.
Deposit date:2004-04-26
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structure and Mechanism of Serine Acetyltransferase from Escherichia coli
J.Biol.Chem., 279, 2004
2WU9
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CRYSTAL STRUCTURE OF PEROXISOMAL KAT2 FROM ARABIDOPSIS THALIANA
Descriptor:3-KETOACYL-COA THIOLASE 2, PEROXISOMAL, 1,2-ETHANEDIOL
Authors:Pye, V.E., Christensen, C.E., Dyer, J.H., Arent, S., Henriksen, A.
Deposit date:2009-10-01
Release date:2010-05-12
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Peroxisomal Plant 3-Ketoacyl-Coa Thiolases Structure and Activity are Regulated by a Sensitive Redox Switch
J.Biol.Chem., 285, 2010
2WUA
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STRUCTURE OF THE PEROXISOMAL 3-KETOACYL-COA THIOLASE FROM SUNFLOWER
Descriptor:ACETOACETYL COA THIOLASE
Authors:Pye, V.E., Christensen, C.E., Dyer, J.H., Arent, S., Henriksen, A.
Deposit date:2009-10-01
Release date:2010-05-12
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Peroxisomal Plant 3-Ketoacyl-Coa Thiolases Structure and Activity are Regulated by a Sensitive Redox Switch
J.Biol.Chem., 285, 2010
4B6D
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STRUCTURE OF THE ATYPICAL C1 DOMAIN OF MGCRACGAP
Descriptor:RAC GTPASE-ACTIVATING PROTEIN 1, GLYCEROL, ZINC ION
Authors:Pye, V.E., Lekomtsev, S., Petronczki, M., Cherepanov, P.
Deposit date:2012-08-09
Release date:2012-12-12
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Centralspindlin Links the Mitotic Spindle to the Plasma Membrane During Cytokinesis.
Nature, 492, 2012
5LLJ
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MAEDI-VISNA VIRUS (MVV) INTEGRASE C-TERMINAL DOMAIN (RESIDUES 220-276)
Descriptor:Integrase, CHLORIDE ION
Authors:Pye, V.E., Maskell, D.P., Cherepanov, P.
Deposit date:2016-07-27
Release date:2017-01-18
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:A supramolecular assembly mediates lentiviral DNA integration.
Science, 355, 2017
5M0R
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CRYO-EM RECONSTRUCTION OF THE MAEDI-VISNA VIRUS (MVV) STRAND TRANSFER COMPLEX
Descriptor:integrase, vDNA, non-transfered strand, ...
Authors:Pye, V.E., Ballandras-Colas, A., Maskell, D., Locke, J., Kotecha, A., Costa, A., Cherepanov, P.
Deposit date:2016-10-05
Release date:2017-01-18
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:A supramolecular assembly mediates lentiviral DNA integration.
Science, 355, 2017
5ME9
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CRYSTAL STRUCTURE OF YEAST CDT1 (N TERMINAL AND MIDDLE DOMAIN), FORM 1.
Descriptor:Cell division cycle protein CDT1, SULFATE ION, GLYCEROL
Authors:Pye, V.E., Frigola, J., Diffley, J.F.X., Cherepanov, P.
Deposit date:2016-11-14
Release date:2017-05-17
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cdt1 stabilizes an open MCM ring for helicase loading.
Nat Commun, 8, 2017
5MEA
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CRYSTAL STRUCTURE OF YEAST CDT1 (N TERMINAL AND MIDDLE DOMAIN), FORM 2.
Descriptor:Cell division cycle protein CDT1, SULFATE ION, GLYCEROL
Authors:Pye, V.E., Frigola, J., Diffley, J.F.X., Cherepanov, P.
Deposit date:2016-11-14
Release date:2017-05-17
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.152 Å)
Cite:Cdt1 stabilizes an open MCM ring for helicase loading.
Nat Commun, 8, 2017
5MEB
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CRYSTAL STRUCTURE OF YEAST CDT1 C-TERMINAL DOMAIN
Descriptor:Cell division cycle protein CDT1, SULFATE ION
Authors:Pye, V.E., Frigola, J., Diffley, J.F.X., Cherepanov, P.
Deposit date:2016-11-14
Release date:2017-05-17
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cdt1 stabilizes an open MCM ring for helicase loading.
Nat Commun, 8, 2017
5MEC
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CRYSTAL STRUCTURE OF YEAST CDT1 MIDDLE DOMAIN (RESIDUES 294-433)
Descriptor:Cell division cycle protein CDT1
Authors:Pye, V.E., Frigola, J., Diffley, J.F.X., Cherepanov, P.
Deposit date:2016-11-14
Release date:2017-05-17
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Cdt1 stabilizes an open MCM ring for helicase loading.
Nat Commun, 8, 2017
5MLU
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CRYSTAL STRUCTURE OF THE PFV GAG CBS BOUND TO A MONONUCLEOSOME
Descriptor:Histone H3.2, Histone H4, Histone H2A type 1, ...
Authors:Pye, V.E., Maskell, D.P., Lesbats, P., Cherepanov, P.
Deposit date:2016-12-07
Release date:2017-05-10
Last modified:2017-05-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for spumavirus GAG tethering to chromatin.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NO1
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CRYSTAL STRUCTURE OF THE PROTOTYPE FOAMY VIRUS (PFV) INTASOME IN COMPLEX WITH MAGNESIUM AND THE INSTI XZ407 (COMPOUND 5G)
Descriptor:Integrase, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ...
Authors:Pye, V.E., Cherepanov, P.
Deposit date:2017-04-10
Release date:2017-08-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors.
J. Med. Chem., 60, 2017
1R7R
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THE CRYSTAL STRUCTURE OF MURINE P97/VCP AT 3.6A
Descriptor:Transitional endoplasmic reticulum ATPase, ADENOSINE-5'-DIPHOSPHATE
Authors:Huyton, T., Pye, V.E., Briggs, L.C., Flynn, T.C., Beuron, F., Kondo, H., Ma, J., Zhang, X., Freemont, P.S.
Deposit date:2003-10-22
Release date:2003-12-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The crystal structure of murine p97/VCP at 3.6A
J.Struct.Biol., 144, 2003
2PJH
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STRCTURAL MODEL OF THE P97 N DOMAIN- NPL4 UBD COMPLEX
Descriptor:Nuclear protein localization protein 4 homolog, Transitional endoplasmic reticulum ATPase
Authors:Isaacson, R., Pye, V.E., Simpson, S., Meyer, H.H., Zhang, X., Freemont, P.
Deposit date:2007-04-16
Release date:2007-05-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Detailed structural insights into the p97-Npl4-Ufd1 interface.
J.Biol.Chem., 282, 2007
2WTB
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ARABIDOPSIS THALIANA MULTIFUCTIONAL PROTEIN, MFP2
Descriptor:FATTY ACID MULTIFUNCTIONAL PROTEIN (ATMFP2)
Authors:Arent, S., Pye, V.E., Christensen, C.E., Norgaard, A., Henriksen, A.
Deposit date:2009-09-15
Release date:2010-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Multi-Functional Protein in Peroxisomal Beta-Oxidation. Structure and Substrate Specificity of the Arabidopsis Thaliana Protein, Mfp2
J.Biol.Chem., 285, 2010
2YMT
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GAMMA 2 ADAPTIN EAR DOMAIN CRYSTAL STRUCTURE WITH PHAGE PEPTIDE GEEWGPWV
Descriptor:AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2, PHAGE DISPLAY DERIVED GAMMA 2 ADAPTIN EAR DOMAIN BINDING PEPTIDE, 1,3-PROPANDIOL
Authors:Juergens, M.C., Voros, J., Rautureau, G., Shepherd, D., Pye, V.E., Muldoon, J., Johnson, C.M., Ashcroft, A., Freund, S.M.V., Ferguson, N.
Deposit date:2012-10-10
Release date:2013-07-10
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:The Hepatitis B Virus Pres1 Domain Hijacks Host Trafficking Proteins by Motif Mimicry.
Nat.Chem.Biol., 9, 2013
3ZE3
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - DELTA7
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Li, D., Pye, V.E., Lyons, J.A., Vogeley, L., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
3ZE4
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - WILD-TYPE
Descriptor:DIACYLGLYCEROL KINASE
Authors:Li, D., Lyons, J.A., Pye, V.E., Vogeley, L., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.702 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
3ZE5
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - DELTA4
Descriptor:DIACYLGLYCEROL KINASE
Authors:Li, D., Vogeley, L., Pye, V.E., Lyons, J.A., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
3ZHF
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GAMMA 2 ADAPTIN EAR DOMAIN CRYSTAL STRUCTURE WITH PRES1 SITE1 PEPTIDE NPDWDFN
Descriptor:AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2, LARGE ENVELOPE PROTEIN, DI(HYDROXYETHYL)ETHER, ...
Authors:Juergens, M.C., Voros, J., Rautureau, G., Shepherd, D., Pye, V.E., Muldoon, J., Johnson, C.M., Ashcroft, A., Freund, S.M.V., Ferguson, N.
Deposit date:2012-12-21
Release date:2013-07-10
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Hepatitis B Virus Pres1 Domain Hijacks Host Trafficking Proteins by Motif Mimicry.
Nat.Chem.Biol., 9, 2013
4AFK
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IN MESO STRUCTURE OF ALGINATE TRANSPORTER, ALGE, FROM PSEUDOMONAS AERUGINOSA, PAO1
Descriptor:ALGINATE PRODUCTION PROTEIN ALGE, CALCIUM ION, CITRATE ANION, ...
Authors:Tan, J., Pye, V.E., Aragao, D., Caffrey, M.
Deposit date:2012-01-19
Release date:2013-02-06
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.897 Å)
Cite:A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
4AZL
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IN MESO STRUCTURE OF ALGINATE TRANSPORTER, ALGE, FROM PSEUDOMOAS AERUGINOSA, PAO1, CRYSTAL FORM 2.
Descriptor:ALGINATE PRODUCTION PROTEIN ALGE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, CALCIUM ION, ...
Authors:Tan, J., Pye, V.E., Aragao, D., Caffrey, M.
Deposit date:2012-06-26
Release date:2013-07-03
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
4B61
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IN MESO STRUCTURE OF ALGINATE TRANSPORTER, ALGE, FROM PSEUDOMOAS AERUGINOSA, PAO1. CRYSTAL FORM 3.
Descriptor:ALGINATE PRODUCTION PROTEIN ALGE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, LAURYL DIMETHYLAMINE-N-OXIDE, ...
Authors:Tan, J., Pye, V.E., Aragao, D., Caffrey, M.
Deposit date:2012-08-08
Release date:2013-07-17
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:A Conformational Landscape for Alginate Secretion Across the Outer Membrane of Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 70, 2014
4BCX
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GAMMA 2 ADAPTIN EAR DOMAIN CRYSTAL STRUCTURE
Descriptor:AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2, IMIDAZOLE, 1,3-PROPANDIOL
Authors:Juergens, M.C., Voros, J., Rautureau, G., Shepherd, D., Pye, V.E., Muldoon, J., Johnson, C.M., Ashcroft, A., Freund, S.M.V., Ferguson, N.
Deposit date:2012-10-03
Release date:2013-07-10
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Hepatitis B Virus Pres1 Domain Hijacks Host Trafficking Proteins by Motif Mimicry.
Nat.Chem.Biol., 9, 2013
5FRM
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CRYSTAL STRUCTURE OF THE PROTOTYPE FOAMY VIRUS (PFV) INTASOME IN COMPLEX WITH MAGNESIUM AND THE INSTI XZ384 (COMPOUND 4A)
Descriptor:PFV INTEGRASE, 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP *TP*CP*GP*CP*A)-3', 5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP *AP*CP*A)-3', ...
Authors:Maskell, D.P., Pye, V.E., Cherepanov, P.
Deposit date:2015-12-18
Release date:2016-02-17
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant Mutant Integrases.
Acs Chem.Biol., 11, 2016
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