Author results

1PZ5
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STRUCTURAL BASIS OF PEPTIDE-CARBOHYDRATE MIMICRY IN AN ANTIBODY COMBINING SITE
Descriptor:Light chain of Fab (SYA/J6), Heavy chain of Fab (SYA/J6), Octapeptide (MDWNMHAA)
Authors:Vyas, N.K., Vyas, M.N., Chervenak, M.C., Bundle, D.R., Pinto, B.M., Quiocho, F.A.
Deposit date:2003-07-09
Release date:2003-11-18
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of peptide-carbohydrate mimicry in an antibody combining site.
Proc.Natl.Acad.Sci.USA, 100, 2003
1M71
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CRYSTAL STRUCTURE OF A MONOCLONAL FAB SPECIFIC FOR SHIGELLA FLEXNERI Y LIPOPOLYSACCHARIDE
Descriptor:light chain of the monoclonal antibody Fab SYA/J6, heavy chain of the monoclonal antibody Fab SYA/J6
Authors:Vyas, N.K., Vyas, M.N., Chervenak, M.C., Johnson, M.A., Pinto, B.M., Bundle, D.R., Quiocho, F.A.
Deposit date:2002-07-18
Release date:2003-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodyanamics
Biochemistry, 41, 2002
1M7D
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CRYSTAL STRUCTURE OF A MONOCLONAL FAB SPECIFIC FOR SHIGELLA FLEXNERI Y LIPOPOLYSACCHARIDE COMPLEXED WITH A TRISACCHARIDE
Descriptor:light chain of the monoclonal antibody Fab SYA/J6, heavy chain of the monoclonal antibody Fab SYA/J6, ALPHA-L-RHAMNOSE, ...
Authors:Vyas, N.K., Vyas, M.N., Chervenak, M.C., Johnson, M.A., Pinto, B.M., Bundle, D.R., Quiocho, F.A.
Deposit date:2002-07-19
Release date:2003-07-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodynamics
Biochemistry, 41, 2002
1M7I
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CRYSTAL STRUCTURE OF A MONOCLONAL FAB SPECIFIC FOR SHIGELLA FLEXNERI Y LIPOPOLYSACCHARIDE COMPLEXED WITH A PENTASACCHARIDE
Descriptor:light chain of the monoclonal antibody Fab SYA/J6, heavy chain of the monoclonal antibody Fab SYA/J6, ALPHA-L-RHAMNOSE, ...
Authors:Vyas, N.K., Vyas, M.N., Chervenak, M.C., Johnson, M.A., Pinto, B.M., Bundle, D.R., Quiocho, F.A.
Deposit date:2002-07-19
Release date:2003-07-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodynamics
Biochemistry, 41, 2002
1R33
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GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH 5-THIO-D-MANNOPYRANOSYLAMINE
Descriptor:putative golgi alpha-mannosidase II, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Kuntz, D.A., Xin, W., Kavelekar, L.M., Rose, D.R., Pinto, B.M.
Deposit date:2003-09-30
Release date:2004-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:5-Thio-d-glycopyranosylamines and their amidinium salts as potential transition-state mimics of glycosyl hydrolases: synthesis, enzyme inhibitory activities, X-ray crystallography, and molecular modeling
TETRAHEDRON ASYMMETRY, 16, 2005
1R34
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GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH 5-THIO-D-MANNOPYRANOSYLAMIDINIUM SALT
Descriptor:putative golgi alpha-mannosidase II, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Kuntz, D.A., Xin, W., Kavelekar, L.M., Rose, D.R., Pinto, B.M.
Deposit date:2003-09-30
Release date:2004-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:5-Thio-d-glycopyranosylamines and their amidinium salts as potential transition-state mimics of glycosyl hydrolases: synthesis, enzyme inhibitory activities, X-ray crystallography, and molecular modeling
TETRAHEDRON ASYMMETRY, 16, 2005
1TQS
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GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH SALACINOL
Descriptor:Alpha-mannosidase II, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Kuntz, D.A., Ghavami, A., Johnston, B.D., Pinto, B.M., Rose, D.R.
Deposit date:2004-06-18
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystallographic analysis of the interactions of Drosophila melanogaster Golgi alpha-mannosidase II with the naturally occurring glycomimetic salacinol and its analogues
Tetrahedron Asymmetry, 16, 2005
1TQT
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GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH A DIASTEREOMER OF SALACINOL
Descriptor:Alpha-mannosidase II, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Kuntz, D.A., Ghavami, A., Johnston, B.D., Pinto, B.M., Rose, D.R.
Deposit date:2004-06-18
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic analysis of the interactions of Drosophila melanogaster Golgi alpha-mannosidase II with the naturally occurring glycomimetic salacinol and its analogues
Tetrahedron Asymmetry, 16, 2005
1TQU
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GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH THE SALACINOL ANALOG GHAVAMIOL
Descriptor:Alpha-mannosidase II, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ZINC ION, ...
Authors:Kuntz, D.A., Ghavami, A., Johnston, B.D., Pinto, B.M., Rose, D.R.
Deposit date:2004-06-18
Release date:2005-01-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystallographic analysis of the interactions of Drosophila melanogaster Golgi alpha-mannosidase II with the naturally occurring glycomimetic salacinol and its analogues
Tetrahedron Asymmetry, 16, 2005
1TQV
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GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH SELENO-SALACINOL (BLINTOL)
Descriptor:Alpha-mannosidase II, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ZINC ION, ...
Authors:Kuntz, D.A., Ghavami, A., Johnston, B.D., Pinto, B.M., Rose, D.R.
Deposit date:2004-06-18
Release date:2005-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystallographic analysis of the interactions of Drosophila melanogaster Golgi alpha-mannosidase II with the naturally occurring glycomimetic salacinol and its analogues
TETRAHEDRON ASYMMETRY, 16, 2005
1TQW
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GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH A DIASTEREOMER OF SELENO-SALACINOL
Descriptor:Alpha-mannosidase II, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Kuntz, D.A., Ghavami, A., Johnston, B.D., Pinto, B.M., Rose, D.R.
Deposit date:2004-06-18
Release date:2005-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Insights into the Mechanism of Drosophila melanogaster Golgi a-Mannosidase II Through Crystallographic Analysis of the Interactions with Analogues of the Naturally Occurring Glycomimetic Salacinol
TETRAHEDRON ASYMMETRY, 16, 2005
4D0T
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GALNAC-T2 CRYSTAL SOAKED WITH UDP-GALNAC, EA2 PEPTIDE AND MANGANESE
Descriptor:POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2, PEPTIDE, MANGANESE (II) ION, ...
Authors:Lira-Navarrete, E., Iglesias-Fernandez, J., Zandberg, W.F., Companon, I., Kong, Y., Corzana, F., Pinto, B.M., Clausen, H., Peregrina, J.M., Vocadlo, D., Rovira, C., Hurtado-Guerrero, R.
Deposit date:2014-04-30
Release date:2014-05-28
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Substrate-Guided Front-Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N-Acetylgalactosaminyltransferase 2.
Angew.Chem.Int.Ed.Engl., 53, 2014
4D0Z
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GALNAC-T2 CRYSTAL SOAKED WITH UDP-5SGALNAC, MEA2 AND MANGANESE (HIGHER RESOLUTION DATASET)
Descriptor:POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2, PEPTIDE, MANGANESE (II) ION, ...
Authors:Lira-Navarrete, E., Iglesias-Fernandez, J., Zandberg, W.F., Companon, I., Kong, Y., Corzana, F., Pinto, B.M., Clausen, H., Peregrina, J.M., Vocadlo, D., Rovira, C., Hurtado-Guerrero, R.
Deposit date:2014-04-30
Release date:2014-05-28
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Substrate-Guided Front-Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N- Acetylgalactosaminyltransferase 2.
Angew.Chem.Int.Ed.Engl., 53, 2014
4D11
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GALNAC-T2 CRYSTAL SOAKED WITH UDP-5SGALNAC, MEA2 PEPTIDE AND MANGANESE (LOWER RESOLUTION DATASET)
Descriptor:POLYPEPTIDE GALNAC-TRANSFERASE T2, PEPTIDE, MANGANESE (II) ION, ...
Authors:Lira-Navarrete, E., Iglesias-Fernandez, J., Zandberg, W.F., Companon, I., Kong, Y., Corzana, F., Pinto, B.M., Clausen, H., Peregrina, J.M., Vocadlo, D., Rovira, C., Hurtado-Guerrero, R.
Deposit date:2014-05-01
Release date:2014-05-28
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Substrate-Guided Front-Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N- Acetylgalactosaminyltransferase 2.
Angew.Chem.Int.Ed.Engl., 53, 2014
2OW6
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GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH (1R,5S,6S,7R,8S)-1-THIONIABICYCLO[4.3.0]NONAN-5,7,8-TRIOL CHLORIDE
Descriptor:Alpha-mannosidase 2, N-ACETYL-D-GLUCOSAMINE, PHOSPHATE ION, ...
Authors:Kuntz, D.A.
Deposit date:2007-02-15
Release date:2008-01-08
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Binding of sulfonium-ion analogues of di-epi-swainsonine and 8-epi-lentiginosine to Drosophila Golgi alpha-mannosidase II: The role of water in inhibitor binding.
Proteins, 71, 2008
2OW7
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GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH (1R,6S,7R,8S)-1-THIONIABICYCLO[4.3.0]NONAN-7,8-DIOL CHLORIDE
Descriptor:Alpha-mannosidase 2, N-ACETYL-D-GLUCOSAMINE, SULFATE ION, ...
Authors:Kuntz, D.A.
Deposit date:2007-02-15
Release date:2008-01-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Binding of sulfonium-ion analogues of di-epi-swainsonine and 8-epi-lentiginosine to Drosophila Golgi alpha-mannosidase II: The role of water in inhibitor binding.
Proteins, 71, 2008
3L4T
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CRYSTAL COMPLEX OF N-TERMINAL HUMAN MALTASE-GLUCOAMYLASE WITH BJ2661
Descriptor:Maltase-glucoamylase, intestinal, (1R,2S)-1-[(1S)-1,2-dihydroxyethyl]-3-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-2-hydroxypropyl sulfate, ...
Authors:Sim, L., Rose, D.R.
Deposit date:2009-12-21
Release date:2010-02-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.
Biochemistry, 49, 2010
3L4U
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CRYSTAL COMPLEX OF N-TERMINAL HUMAN MALTASE-GLUCOAMYLASE WITH DE-O-SULFONATED KOTALANOL
Descriptor:Maltase-glucoamylase, intestinal, (2R,3S,4S)-1-[(2S,3S,4R,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl]-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium (non-preferred name), ...
Authors:Sim, L., Rose, D.R.
Deposit date:2009-12-21
Release date:2010-02-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.
Biochemistry, 49, 2010
3L4V
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CRYSTAL COMPLEX OF N-TERMINAL HUMAN MALTASE-GLUCOAMYLASE WITH KOTALANOL
Descriptor:Maltase-glucoamylase, intestinal, (1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate, ...
Authors:Sim, L., Rose, D.R.
Deposit date:2009-12-21
Release date:2010-02-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.
Biochemistry, 49, 2010
3L4W
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CRYSTAL COMPLEX OF N-TERMINAL HUMAN MALTASE-GLUCOAMYLASE WITH MIGLITOL
Descriptor:Maltase-glucoamylase, intestinal, (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, ...
Authors:Sim, L., Rose, D.R.
Deposit date:2009-12-21
Release date:2010-02-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.
Biochemistry, 49, 2010
3L4X
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CRYSTAL COMPLEX OF N-TERMINAL HUMAN MALTASE-GLUCOAMYLASE WITH NR4-8
Descriptor:Maltase-glucoamylase, intestinal, (1S,2R,3S,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate, ...
Authors:Sim, L., Rose, D.R.
Deposit date:2009-12-21
Release date:2010-02-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.
Biochemistry, 49, 2010
3L4Y
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CRYSTAL COMPLEX OF N-TERMINAL HUMAN MALTASE-GLUCOAMYLASE WITH NR4-8II
Descriptor:Maltase-glucoamylase, intestinal, (1S,2R,3S,4R)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate, ...
Authors:Sim, L., Rose, D.R.
Deposit date:2009-12-21
Release date:2010-02-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.
Biochemistry, 49, 2010
3L4Z
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CRYSTAL COMPLEX OF N-TERMINAL HUMAN MALTASE-GLUCOAMYLASE WITH SALACINOL
Descriptor:Maltase-glucoamylase, intestinal, 1,4-DIDEOXY-1,4-[[2R,3R)-2,4-DIHYDROXY-3-(SULFOXY)BUTYL]EPISULFONIUMYLIDENE]-D-ARABINITOL INNER SALT, ...
Authors:Sim, L., Rose, D.R.
Deposit date:2009-12-21
Release date:2010-02-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.
Biochemistry, 49, 2010
3LPO
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SUCRASE-ISOMALTASE
Descriptor:Sucrase-isomaltase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Sim, L., Rose, D.R.
Deposit date:2010-02-05
Release date:2010-03-31
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains.
J.Biol.Chem., 285, 2010
3LPP
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CRYSTAL COMPLEX OF N-TERMINAL SUCRASE-ISOMALTASE WITH KOTALANOL
Descriptor:Sucrase-isomaltase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Sim, L., Rose, D.R.
Deposit date:2010-02-05
Release date:2010-03-31
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains.
J.Biol.Chem., 285, 2010
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