Golgi alpha-mannosidase II complex with (1R,6S,7R,8S)-1-thioniabicyclo[4.3.0]nonan-7,8-diol chloride

Summary for 2OW7

Related1HTY 1HWW 1HXK 1PS3 1QWN 1QWU 1QX1 1R33 1R34 1TQS 1TQT 1TQU 1TQV 1TQW 2ALW 2F18 2F1A 2F1B 2F7O 2F7Q 2F7R 2FYV 2OW6
DescriptorAlpha-mannosidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (7 entities in total)
Functional Keywordsglycosyl hydrolase family 38, hydrolase
Biological sourceDrosophila melanogaster (fruit fly)
Cellular locationGolgi apparatus membrane; Single-pass type II membrane protein Q24451
Total number of polymer chains1
Total molecular weight120761.99
Kuntz, D.A. (deposition date: 2007-02-15, release date: 2008-01-08, Last modification date: 2020-07-29)
Primary citation
Kumar, N.S.,Kuntz, D.A.,Wen, X.,Pinto, B.M.,Rose, D.R.
Binding of sulfonium-ion analogues of di-epi-swainsonine and 8-epi-lentiginosine to Drosophila Golgi alpha-mannosidase II: The role of water in inhibitor binding.
Proteins, 71:1484-1496, 2008
PubMed: 18076078 (PDB entries with the same primary citation)
DOI: 10.1002/prot.21850
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1755 0.5% 2.0% 3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16