Author results

1A37
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14-3-3 PROTEIN ZETA BOUND TO PS-RAF259 PEPTIDE
Descriptor:14-3-3 PROTEIN ZETA, PS-RAF259 PEPTIDE LSQRQRST(SEP)TPNVHM
Authors:Petosa, C., Masters, S.C., Pohl, J., Wang, B., Fu, H., Liddington, R.C.
Deposit date:1998-01-28
Release date:1999-03-02
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove.
J.Biol.Chem., 273, 1998
1A38
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14-3-3 PROTEIN ZETA BOUND TO R18 PEPTIDE
Descriptor:14-3-3 PROTEIN ZETA, R18 PEPTIDE (PHCVPRDLSWLDLEANMCLP)
Authors:Petosa, C., Masters, S.C., Pohl, J., Wang, B., Fu, H., Liddington, R.C.
Deposit date:1998-01-28
Release date:1999-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove.
J.Biol.Chem., 273, 1998
1ACC
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ANTHRAX PROTECTIVE ANTIGEN
Descriptor:ANTHRAX PROTECTIVE ANTIGEN, CALCIUM ION
Authors:Petosa, C., Liddington, R.C.
Deposit date:1997-02-05
Release date:1998-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the anthrax toxin protective antigen.
Nature, 385, 1997
1W9C
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PROTEOLYTIC FRAGMENT OF CRM1 SPANNING SIX C-TERMINAL HEAT REPEATS
Descriptor:CRM1 PROTEIN
Authors:Petosa, C., Schoehn, G., Askjaer, P., Bauer, U., Moulin, M., Steuerwald, U., Soler-Lopez, M., Baudin, F., Mattaj, I.W., Muller, C.W.
Deposit date:2004-10-08
Release date:2004-12-03
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Architecture of Crm1-Exportin 1 Suggests How Cooperativity is Achieved During Formation of a Nuclear Export Complex
Mol.Cell, 16, 2004
2C9L
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STRUCTURE OF THE EPSTEIN-BARR VIRUS ZEBRA PROTEIN
Descriptor:5'-D(*AP*AP*GP*CP*AP*CP*TP*GP*AP*CP *TP*CP*AP*TP*GP*AP*AP*GP*T)-3', 5'-D(*AP*CP*TP*TP*CP*AP*CP*TP*GP*AP *GP*TP*CP*AP*GP*TP*GP*CP*T)-3', BZLF1 TRANS-ACTIVATOR PROTEIN
Authors:Petosa, C., Morand, P., Baudin, F., Moulin, M., Artero, J.B., Muller, C.W.
Deposit date:2005-12-13
Release date:2006-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Basis of Lytic Cycle Activation by the Epstein-Barr Virus Zebra Protein
Mol.Cell, 21, 2006
2C9N
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STRUCTURE OF THE EPSTEIN-BARR VIRUS ZEBRA PROTEIN AT APPROXIMATELY 3. 5 ANGSTROM RESOLUTION
Descriptor:5'-D(*CP*AP*CP*TP*GP*AP*CP*TP*CP*AP *T)-3', 5'-D(*CP*AP*TP*GP*AP*GP*TP*CP*AP*GP *T)-3', BZLF1 TRANS-ACTIVATOR PROTEIN
Authors:Petosa, C., Morand, P., Baudin, F., Moulin, M., Artero, J.B., Muller, C.W.
Deposit date:2005-12-13
Release date:2006-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Basis of Lytic Cycle Activation by the Epstein-Barr Virus Zebra Protein
Mol.Cell, 21, 2006
5N13
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SECOND BROMODOMAIN (BD2) FROM CANDIDA ALBICANS BDF1 IN THE UNBOUND FORM
Descriptor:Bromodomain-containing factor 1, GLYCEROL
Authors:Mietton, F., Ferri, E., Champlebouxm, M., Zala, N., Maubon, D., Zhou, Y., Harbut, M., Spittler, D., Garnaud, C., Courcon, M., Chauvel, M., d'Enfert, C., Kashemirov, B.A., Hull, M., Cornet, M., McKenna, C.E., Govin, J., Petosa, C.
Deposit date:2017-02-04
Release date:2017-05-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Selective BET bromodomain inhibition as an antifungal therapeutic strategy.
Nat Commun, 8, 2017
5N15
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FIRST BROMODOMAIN (BD1) FROM CANDIDA ALBICANS BDF1 IN THE UNBOUND FORM
Descriptor:Bromodomain-containing factor 1, IODIDE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Mietton, F., Ferri, E., Champleboux, M., Zala, N., Maubon, D., Zhou, Y., Harbut, M., Spittler, D., Garnaud, C., Courcon, M., Chauvel, M., d'Enfert, C., Kashemirov, B.A., Hull, M., Cornet, M., McKenna, C.E., Govin, J., Petosa, C.
Deposit date:2017-02-05
Release date:2017-05-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Selective BET bromodomain inhibition as an antifungal therapeutic strategy.
Nat Commun, 8, 2017
5N16
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FIRST BROMODOMAIN (BD1) FROM CANDIDA ALBICANS BDF1 BOUND TO A DIBENZOTHIAZEPINONE (COMPOUND 1)
Descriptor:Bromodomain-containing factor 1, 5-cyclopropyl-2-(5-pyrazin-2-yl-1,2,4-oxadiazol-3-yl)benzo[b][1,4]benzothiazepin-6-one, NICKEL (II) ION, ...
Authors:Mietton, F., Ferri, E., Champleboux, M., Zala, N., Maubon, D., Zhou, Y., Harbut, M., Spittler, D., Garnaud, C., Courcon, M., Chauvel, M., d'Enfert, C., Kashemirov, B.A., Hull, M., Cornet, M., McKenna, C.E., Govin, J., Petosa, C.
Deposit date:2017-02-05
Release date:2017-05-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Selective BET bromodomain inhibition as an antifungal therapeutic strategy.
Nat Commun, 8, 2017
5N17
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FIRST BROMODOMAIN (BD1) FROM CANDIDA ALBICANS BDF1 BOUND TO A DIBENZOTHIAZEPINONE (COMPOUND 3)
Descriptor:Bromodomain-containing factor 1, (2~{S})-~{N}-(5-methyl-6-oxidanylidene-benzo[b][1,4]benzothiazepin-2-yl)oxolane-2-carboxamide, SULFATE ION
Authors:Mietton, F., Ferri, E., Champleboux, M., Zala, N., Maubon, D., Zhou, Y., Harbut, M., Spittler, D., Garnaud, C., Courcon, M., Chauvon, M., d'Enfer, C., Kashemirov, B.A., Hull, M., Cornet, M., McKenna, C.E., Govin, J., Petosa, C.
Deposit date:2017-02-05
Release date:2017-05-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Selective BET bromodomain inhibition as an antifungal therapeutic strategy.
Nat Commun, 8, 2017
5N18
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SECOND BROMODOMAIN (BD2) FROM CANDIDA ALBICANS BDF1 BOUND TO AN IMIDAZOPYRIDINE (COMPOUND 2)
Descriptor:Bromodomain-containing factor 1, 4-[8-methyl-3-[(4-methylphenyl)amino]imidazo[1,2-a]pyridin-2-yl]phenol, GLYCEROL
Authors:Mietton, F., Ferri, E., Champleboux, M., Zala, N., Maubon, D., Zhou, Y., Harbut, M., Spittler, D., Garnaud, C., Courcon, M., Chauvel, M., d'Enfert, C., Kashemirov, B.A., Hull, M., Cornet, M., McKenna, C.E., Govin, J., Petosa, C.
Deposit date:2017-02-05
Release date:2017-05-31
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Selective BET bromodomain inhibition as an antifungal therapeutic strategy.
Nat Commun, 8, 2017
2Y8F
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STRUCTURE OF THE RAN-BINDING DOMAIN FROM HUMAN RANBP3 (WILD TYPE)
Descriptor:RAN-BINDING PROTEIN 3, CHLORIDE ION, GLYCEROL
Authors:Langer, K., Dian, C., Rybin, V., Muller, C.W., Petosa, C.
Deposit date:2011-02-06
Release date:2011-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights Into the Function of the Crm1 Cofactor Ranbp3 from the Structure of its Ran-Binding Domain
Plos One, 6, 2011
2Y8G
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STRUCTURE OF THE RAN-BINDING DOMAIN FROM HUMAN RANBP3 (E352A-R353V DOUBLE MUTANT)
Descriptor:RAN-BINDING PROTEIN 3, SULFATE ION
Authors:Langer, K., Dian, C., Rybin, V., Muller, C.W., Petosa, C.
Deposit date:2011-02-06
Release date:2011-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Insights Into the Function of the Crm1 Cofactor Ranbp3 from the Structure of its Ran-Binding Domain
Plos One, 6, 2011
4BSM
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CRYSTAL STRUCTURE OF THE NUCLEAR EXPORT RECEPTOR CRM1 (EXPORTIN-1) LACKING THE C-TERMINAL HELICAL EXTENSION AT 4.5A
Descriptor:EXPORTIN-1
Authors:Dian, C., Bernaudat, F., Langer, K., Oliva, M.F., Fornerod, M., Schoehn, G., Muller, C.W., Petosa, C.
Deposit date:2013-06-10
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix.
Structure, 21, 2013
4BSN
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CRYSTAL STRUCTURE OF THE NUCLEAR EXPORT RECEPTOR CRM1 (EXPORTIN-1) LACKING THE C-TERMINAL HELICAL EXTENSION AT 4.1A
Descriptor:EXPORTIN-1
Authors:Dian, C., Bernaudat, F., Langer, K., Oliva, M.F., Fornerod, M., Schoehn, G., Muller, C.W., Petosa, C.
Deposit date:2013-06-11
Release date:2013-07-31
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix.
Structure, 21, 2013
5NL0
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CRYSTAL STRUCTURE OF A 197-BP PALINDROMIC 601L NUCLEOSOME IN COMPLEX WITH LINKER HISTONE H1
Descriptor:Histone H3.2, Histone H4, Histone H2A type 1, ...
Authors:Garcia-Saez, I., Petosa, C., Dimitrov, S.
Deposit date:2017-04-03
Release date:2017-05-17
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (5.4 Å)
Cite:Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.
Mol. Cell, 66, 2017
2PYO
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DROSOPHILA NUCLEOSOME CORE
Descriptor:DNA (147-MER), Histone H3, Histone H4, ...
Authors:Clapier, C.R., Petosa, C., Mueller, C.W.
Deposit date:2007-05-16
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer.
Proteins, 71, 2007
1A4O
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14-3-3 PROTEIN ZETA ISOFORM
Descriptor:14-3-3 PROTEIN ZETA
Authors:Liu, D., Bienkowska, J., Petosa, C., Collier, R.J., Fu, H., Liddington, R.C.
Deposit date:1998-02-01
Release date:1999-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the zeta isoform of the 14-3-3 protein.
Nature, 376, 1995
1J7N
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ANTHRAX TOXIN LETHAL FACTOR
Descriptor:Lethal Factor precursor, SULFATE ION, ZINC ION
Authors:Pannifer, A.D., Wong, T.Y., Schwarzenbacher, R., Renatus, M., Petosa, C., Collier, R.J., Bienkowska, J., Lacy, D.B., Park, S., Leppla, S.H., Hanna, P., Liddington, R.C.
Deposit date:2001-05-17
Release date:2001-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the anthrax lethal factor.
Nature, 414, 2001
1JKY
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CRYSTAL STRUCTURE OF THE ANTHRAX LETHAL FACTOR (LF): WILD-TYPE LF COMPLEXED WITH THE N-TERMINAL SEQUENCE OF MAPKK2
Descriptor:Lethal Factor, mitogen-activated protein kinase kinase 2
Authors:Pannifer, A.D., Wong, T.Y., Schwarzenbacher, R., Renatus, M., Petosa, C., Collier, R.J., Bienkowska, J., Lacy, D.B., Park, S., Leppla, S.H., Hanna, P., Liddington, R.C.
Deposit date:2001-07-13
Release date:2001-11-07
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structure of the anthrax lethal factor.
Nature, 414, 2001
1K1A
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CRYSTAL STRUCTURE OF THE ANKYRIN REPEAT DOMAIN OF BCL-3: A UNIQUE MEMBER OF THE IKAPPAB PROTEIN FAMILY
Descriptor:B-cell lymphoma 3-encoded protein
Authors:Michel, F., Soler-Lopez, M., Petosa, C., Cramer, P., Siebenlist, U., Mueller, C.W.
Deposit date:2001-09-24
Release date:2001-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family.
EMBO J., 20, 2001
1K1B
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CRYSTAL STRUCTURE OF THE ANKYRIN REPEAT DOMAIN OF BCL-3: A UNIQUE MEMBER OF THE IKAPPAB PROTEIN FAMILY
Descriptor:B-cell lymphoma 3-encoded protein
Authors:Michel, F., Soler-Lopez, M., Petosa, C., Cramer, P., Siebenlist, U., Mueller, C.W.
Deposit date:2001-09-24
Release date:2001-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family.
EMBO J., 20, 2001
1QGK
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STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA
Descriptor:PROTEIN (IMPORTIN BETA SUBUNIT), PROTEIN (IMPORTIN ALPHA-2 SUBUNIT)
Authors:Cingolani, G., Petosa, C., Weis, K., Muller, C.W.
Deposit date:1999-04-29
Release date:1999-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of importin-beta bound to the IBB domain of importin-alpha.
Nature, 399, 1999
1QGR
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STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA (II CRYSTAL FORM, GROWN AT LOW PH)
Descriptor:PROTEIN (IMPORTIN BETA SUBUNIT), PROTEIN (IMPORTIN ALPHA-2 SUBUNIT)
Authors:Cingolani, G., Petosa, C., Weis, K., Muller, C.W.
Deposit date:1999-05-04
Release date:1999-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of importin-beta bound to the IBB domain of importin-alpha.
Nature, 399, 1999
1UUR
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STRUCTURE OF AN ACTIVATED DICTYOSTELIUM STAT IN ITS DNA-UNBOUND FORM
Descriptor:STATA PROTEIN
Authors:Soler-Lopez, M., Petosa, C., Fukuzawa, M., Ravelli, R., Williams, J.G., Muller, C.W.
Deposit date:2004-01-09
Release date:2004-03-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of an Activated Dictyostelium Stat in its DNA-Unbound Form
Mol.Cell, 13, 2004
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