5N15
First Bromodomain (BD1) from Candida albicans Bdf1 in the unbound form
Summary for 5N15
Entry DOI | 10.2210/pdb5n15/pdb |
Descriptor | Bromodomain-containing factor 1, IODIDE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total) |
Functional Keywords | bromodomain, transcription |
Biological source | Candida albicans (Yeast) |
Cellular location | Nucleus : Q5A4W8 |
Total number of polymer chains | 4 |
Total formula weight | 65156.92 |
Authors | Mietton, F.,Ferri, E.,Champleboux, M.,Zala, N.,Maubon, D.,Zhou, Y.,Harbut, M.,Spittler, D.,Garnaud, C.,Courcon, M.,Chauvel, M.,d'Enfert, C.,Kashemirov, B.A.,Hull, M.,Cornet, M.,McKenna, C.E.,Govin, J.,Petosa, C. (deposition date: 2017-02-05, release date: 2017-05-31, Last modification date: 2024-01-17) |
Primary citation | Mietton, F.,Ferri, E.,Champleboux, M.,Zala, N.,Maubon, D.,Zhou, Y.,Harbut, M.,Spittler, D.,Garnaud, C.,Courcon, M.,Chauvel, M.,d'Enfert, C.,Kashemirov, B.A.,Hull, M.,Cornet, M.,McKenna, C.E.,Govin, J.,Petosa, C. Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nat Commun, 8:15482-15482, 2017 Cited by PubMed: 28516956DOI: 10.1038/ncomms15482 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.37 Å) |
Structure validation
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