Author results

4GFT
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MALARIA INVASION MACHINERY PROTEIN-NANOBODY COMPLEX
分子名称:Myosin A tail domain interacting protein, Nanobody, 1,2-ETHANEDIOL
著者Khamrui, S., Turley, S., Pardon, E., Steyaert, J., Verlinde, C., Fan, E., Bergman, L.W., Hol, W.G.J.
登録日2012-08-03
公開日2013-07-03
最終更新日2015-12-09
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody.
Mol.Biochem.Parasitol., 190, 2013
4I0C
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THE STRUCTURE OF THE CAMELID ANTIBODY CABHUL5 IN COMPLEX WITH HUMAN LYSOZYME
分子名称:Lysozyme C, cAbHuL5 antibody, CHLORIDE ION, ...
著者De Genst, E., Chan, P.H., Pardon, E., Kumita, J.R., Christodoulou, J., Menzer, L., Chirgadze, D.Y., Robinson, C.V., Muyldermans, S., Matagne, A., Wyns, L., Dobson, C.M., Dumoulin, M.
登録日2012-11-16
公開日2013-10-09
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
J.Phys.Chem.B, 117, 2013
4W6W
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CO-COMPLEX STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF WITH INHIBITORY NANOBODY NBFEDF6
分子名称:F18 fimbrial adhesin AC, NbFedF6
著者Moonens, K., De Kerpel, M., Annelies, C., Cox, E., Pardon, E., Remaut, H., De Greve, H.
登録日2014-08-21
公開日2014-12-17
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
4W6X
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CO-COMPLEX STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF WITH INHIBITORY NANOBODY NBFEDF7
分子名称:F18 fimbrial adhesin AC, Nanobody NbFedF7
著者Moonens, K., De Kerpel, M., Coddens, A., Cox, E., Pardon, E., Remaut, H., De Greve, H.
登録日2014-08-21
公開日2014-12-17
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
4W6Y
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CO-COMPLEX STRUCTURE OF THE LECTIN DOMAIN OF F18 FIMBRIAL ADHESIN FEDF WITH INHIBITORY NANOBODY NBFEDF9
分子名称:F18 fimbrial adhesin AC, Nanobody NbFedF9, SULFATE ION
著者Moonens, K., De Kerpel, M., Coddens, A., Cox, E., Pardon, E., Remaut, H., De Greve, H.
登録日2014-08-21
公開日2014-12-17
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
6B73
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CRYSTAL STRUCTURE OF A NANOBODY-STABILIZED ACTIVE STATE OF THE KAPPA-OPIOID RECEPTOR
分子名称:Soluble cytochrome b562, kappa-type opioid receptor, Nanobody, ...
著者Che, T., Majumdar, S., Zaidi, S.A., Kormos, C., McCorvy, J.D., Wang, S., Mosier, P.D., Uprety, R., Vardy, E., Krumm, B.E., Han, G.W., Lee, M.Y., Pardon, E., Steyaert, J., Huang, X.P., Strachan, R.T., Tribo, A.R., Pasternak, G.W., Carroll, I.F., Stevens, R.C., Cherezov, V., Katritch, V., Wacker, D., Roth, B.L.
登録日2017-10-03
公開日2018-01-17
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
Cell, 172, 2018
6GJQ
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HUMAN NBD1 OF CFTR IN COMPLEX WITH NANOBODY T27
分子名称:Cystic fibrosis transmembrane conductance regulator, Nanobody T27, ADENOSINE-5'-TRIPHOSPHATE
著者Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C.
登録日2018-05-16
公開日2019-06-19
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
6GJS
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HUMAN NBD1 OF CFTR IN COMPLEX WITH NANOBODIES D12 AND T4
分子名称:Cystic fibrosis transmembrane conductance regulator, Nanobody D12, Nanobody T4, ...
著者Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C.
登録日2018-05-16
公開日2019-06-26
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
6GJU
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HUMAN NBD1 OF CFTR IN COMPLEX WITH NANOBODIES T2A AND T4
分子名称:Cystic fibrosis transmembrane conductance regulator, Nanobody T4, Nanobody T2a, ...
著者Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C.
登録日2018-05-17
公開日2019-06-26
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
6GK4
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HUMAN NBD1 OF CFTR IN COMPLEX WITH NANOBODIES D12 AND T8
分子名称:Cystic fibrosis transmembrane conductance regulator, Nanobody D12, Nanobody T8, ...
著者Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C.
登録日2018-05-18
公開日2019-06-19
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
6GKD
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HUMAN NBD1 OF CFTR IN COMPLEX WITH NANOBODIES D12 AND G3A
分子名称:Cystic fibrosis transmembrane conductance regulator, Nanobody D12, Nanobody G3a, ...
著者Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C.
登録日2018-05-18
公開日2019-06-19
最終更新日2019-06-26
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
6MXT
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CRYSTAL STRUCTURE OF HUMAN BETA2 ADRENERGIC RECEPTOR BOUND TO SALMETEROL AND NB71
分子名称:Endolysin, Beta-2 adrenergic receptor chimera, nanobody Nb71, ...
著者Masureel, M., Zou, Y., Picard, L.P., van der Westhuizen, E., Mahoney, J.P., Rodrigues, J.P.G.L.M., Mildorf, T.J., Dror, R.O., Shaw, D.E., Bouvier, M., Pardon, E., Steyaert, J., Sunahara, R.K., Weis, W.I., Zhang, C., Kobilka, B.K.
登録日2018-10-31
公開日2018-11-14
実験手法X-RAY DIFFRACTION (2.959342 Å)
主引用文献Structural insights into binding specificity, efficacy and bias of a beta2AR partial agonist.
Nat. Chem. Biol., 14, 2018
4WEM
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CO-COMPLEX STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG VARIANT AC WITH LLAMA SINGLE DOMAIN ANTIBODY V1
分子名称:K88 fimbrial protein AC, Anti-F4+ETEC bacteria VHH variable region, PHOSPHATE ION
著者Moonens, K., Van den Broeck, I., Pardon, E., De Kerpel, M., Remaut, H., De Greve, H.
登録日2014-09-10
公開日2015-02-04
最終更新日2015-04-15
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4WEN
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CO-COMPLEX STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG VARIANT AC WITH LLAMA SINGLE DOMAIN ANTIBODY V2
分子名称:K88 fimbrial protein AC, Anti-F4+ETEC bacteria VHH variable region
著者Moonens, K., Van den Broeck, I., Pardon, E., De Kerpel, M., Remaut, H., De Greve, H.
登録日2014-09-10
公開日2015-02-04
最終更新日2015-04-15
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4WEU
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CO-COMPLEX STRUCTURE OF THE F4 FIMBRIAL ADHESIN FAEG VARIANT AD WITH LLAMA SINGLE DOMAIN ANTIBODY V3
分子名称:Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AD
著者Moonens, K., Van den Broeck, I., Pardon, E., De Kerpel, M., Remaut, H., De Greve, H.
登録日2014-09-11
公開日2015-02-04
最終更新日2015-04-15
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
2X6M
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STRUCTURE OF A SINGLE DOMAIN CAMELID ANTIBODY FRAGMENT IN COMPLEX WITH A C-TERMINAL PEPTIDE OF ALPHA-SYNUCLEIN
分子名称:HEAVY CHAIN VARIABLE DOMAIN FROM DROMEDARY, ALPHA-SYNUCLEIN PEPTIDE
著者DeGenst, E., Guilliams, T., Wellens, J., O'Day, E.M., Waudby, C.A., Meehan, S., Dumoulin, M., Hsu, S.-T.D., Cremades, N., Verschueren, K.H.G., Pardon, E., Wyns, L., Steyaert, J., Christodoulou, J., Dobson, C.M.
登録日2010-02-18
公開日2010-06-23
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structure and Properties of a Complex of Alpha-Synuclein and a Single-Domain Camelid Antibody.
J.Mol.Biol., 402, 2010
5BOP
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CRYSTAL STRUCTURE OF THE ARTIFICIAL NANOBODY OCTARELLINV.1 COMPLEX
分子名称:Nanobody, Octarellin V.1
著者Figueroa, M., Sleutel, M., Pardon, E., Steyaert, J., Martial, J.A., van de Weerdt, C.
登録日2015-05-27
公開日2016-05-25
最終更新日2016-06-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
2YPW
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ATOMIC MODEL FOR THE N-TERMINUS OF TRAO FITTED IN THE FULL-LENGTH STRUCTURE OF THE BACTERIAL PKM101 TYPE IV SECRETION SYSTEM CORE COMPLEX
分子名称:TRAO
著者Rivera-Calzada, A., Fronzes, R., Savva, C.G., Chandran, V., Lian, P.W., Laeremans, T., Pardon, E., Steyaert, J., Remaut, H., Waksman, G., Orlova, E.V.
登録日2012-11-02
公開日2013-04-03
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (12.4 Å)
主引用文献Structure of a Bacterial Type Iv Secretion Core Complex at Subnanometre Resolution.
Embo J., 32, 2013
3ZBI
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FITTING RESULT IN THE O-LAYER OF THE SUBNANOMETER STRUCTURE OF THE BACTERIAL PKM101 TYPE IV SECRETION SYSTEM CORE COMPLEX DIGESTED WITH ELASTASE
分子名称:TRAF PROTEIN, TRAO PROTEIN, TRAN PROTEIN
著者Rivera-Calzada, A., Fronzes, R., Savva, C.G., Chandran, V., Lian, P.W., Laeremans, T., Pardon, E., Steyaert, J., Remaut, H., Waksman, G., Orlova, E.V.
登録日2012-11-10
公開日2013-04-03
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献Structure of a Bacterial Type Iv Secretion Core Complex at Subnanometre Resolution.
Embo J., 32, 2013
1ZMY
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CABBCII-10 VHH FRAMEWORK WITH CDR LOOPS OF CABLYS3 GRAFTED ON IT AND IN COMPLEX WITH HEN EGG WHITE LYSOZYME
分子名称:Antibody cabbcII-10:lys3, Lysozyme C
著者Saerens, D., Pellis, M., Loris, R., Pardon, E., Dumoulin, M., Matagne, A., Wyns, L., Muyldermans, S., Conrath, K.
登録日2005-05-11
公開日2005-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies
J.Mol.Biol., 352, 2005
2X89
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STRUCTURE OF THE BETA2_MICROGLOBULIN INVOLVED IN AMYLOIDOGENESIS
分子名称:ANTIBODY, BETA-2-MICROGLOBULIN
著者Domanska, K., Srinivasan, V., Vanderhaegen, S., Pardon, E., Marquez, J.A., Bellotti, V., Wyns, L., Steyaert, J.
登録日2010-03-07
公開日2011-01-19
最終更新日2013-09-04
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Atomic Structure of a Nanobody-Trapped Domain-Swapped Dimer of an Amyloidogenic {Beta}2-Microglobulin Variant.
Proc.Natl.Acad.Sci.USA, 108, 2011
3CFI
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NANOBODY-AIDED STRUCTURE DETERMINATION OF THE EPSI:EPSJ PSEUDOPILIN HETERDIMER FROM VIBRIO VULNIFICUS
分子名称:Type II secretory pathway, pseudopilin EpsI, PSEUDOPILIN EpsJ, ...
著者Lam, A.Y., Pardon, E., Korotkov, K.V., Steyaert, J., Hol, W.G.J.
登録日2008-03-03
公開日2009-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Nanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus.
J.Struct.Biol., 166, 2009
3EZJ
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE SECRETIN GSPD FROM ETEC DETERMINED WITH THE ASSISTANCE OF A NANOBODY
分子名称:General secretion pathway protein GspD, NANOBODY NBGSPD_7, PHOSPHATE ION, ...
著者Korotkov, K.V., Pardon, E., Steyaert, J., Hol, W.G.
登録日2008-10-22
公開日2009-02-17
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody.
Structure, 17, 2009
3P0G
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STRUCTURE OF A NANOBODY-STABILIZED ACTIVE STATE OF THE BETA2 ADRENOCEPTOR
分子名称:Beta-2 adrenergic receptor, Lysozyme, Camelid Antibody Fragment, ...
著者Rasmussen, S.G.F., Choi, H.-J., Fung, J.J., Pardon, E., Casarosa, P., Chae, P.S., DeVree, B.T., Rosenbaum, D.M., Thian, F.S., Kobilka, T.S., Schnapp, A., Konetzki, I., Sunahara, R.K., Gellman, S.H., Pautsch, A., Steyaert, J., Weis, W.I., Kobilka, B.K.
登録日2010-09-28
公開日2011-01-19
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of a nanobody-stabilized active state of the b2 adrenoceptor
Nature, 469, 2011
3SN6
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CRYSTAL STRUCTURE OF THE BETA2 ADRENERGIC RECEPTOR-GS PROTEIN COMPLEX
分子名称:Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Rasmussen, S.G.F., DeVree, B.T., Zou, Y., Kruse, A.C., Chung, K.Y., Kobilka, T.S., Thian, F.S., Chae, P.S., Pardon, E., Calinski, D., Mathiesen, J.M., Shah, S.T.A., Lyons, J.A., Caffrey, M., Gellman, S.H., Steyaert, J., Skiniotis, G., Weis, W.I., Sunahara, R.K., Kobilka, B.K.
登録日2011-06-28
公開日2011-07-20
最終更新日2017-07-12
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the beta2 adrenergic receptor-Gs protein complex
Nature, 477, 2011