Author results

2K3M
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RV1761C
Descriptor:Rv1761c, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Page, R.C., Moore, J.D., Lee, S., Opella, S.J., Cross, T.A.
Deposit date:2008-05-14
Release date:2009-01-06
Last modified:2013-06-19
Method:SOLUTION NMR
Cite:Backbone structure of a small helical integral membrane protein: A unique structural characterization.
Protein Sci., 18, 2009
3RGH
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STRUCTURE OF FILAMIN A IMMUNOGLOBULIN-LIKE REPEAT 10 FROM HOMO SAPIENS
Descriptor:Filamin-A, ACETATE ION
Authors:Page, R.C., Clark, J., Misra, S.
Deposit date:2011-04-08
Release date:2011-08-03
Last modified:2011-08-17
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structure of filamin A immunoglobulin-like repeat 10 from Homo sapiens.
Acta Crystallogr.,Sect.F, 67, 2011
3TGD
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CRYSTAL STRUCTURE OF THE HUMAN UBIQUITIN-CONJUGATING ENZYME (E2) UBCH5B
Descriptor:Ubiquitin-conjugating enzyme E2 D2
Authors:Page, R.C., Amick, J., Misra, S.
Deposit date:2011-08-17
Release date:2011-08-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b
To be Published
3UGB
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UBCH5C~UBIQUITIN CONJUGATE
Descriptor:Ubiquitin-conjugating enzyme E2 D3, Polyubiquitin-C, GLYCEROL
Authors:Page, R.C., Pruneda, J.N., Klevit, R.E., Misra, S.
Deposit date:2011-11-02
Release date:2012-05-16
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates.
Biochemistry, 51, 2012
3R6B
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CRYSTAL STRUCTURE OF THROMBOSPONDIN-1 TSR DOMAINS 2 AND 3
Descriptor:Thrombospondin-1, 1,2-ETHANEDIOL
Authors:Page, R.C., Klenotic, P.A., Misra, S., Silverstein, R.L.
Deposit date:2011-03-21
Release date:2011-08-10
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.
Protein Expr.Purif., 80, 2011
4GKX
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CRYSTAL STRUCTURE OF A CARBOHYDRATE-BINDING DOMAIN
Descriptor:Protein ERGIC-53, CALCIUM ION, 2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose, ...
Authors:Page, R.C., Zheng, C., Nix, J.C., Misra, S., Zhang, B.
Deposit date:2012-08-13
Release date:2013-06-05
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII).
J.Biol.Chem., 288, 2013
4GKY
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CRYSTAL STRUCTURE OF A CARBOHYDRATE-BINDING DOMAIN
Descriptor:Protein ERGIC-53, CALCIUM ION, ALPHA-D-MANNOSE, ...
Authors:Page, R.C., Zheng, C., Nix, J.C., Misra, S., Zhang, B.
Deposit date:2012-08-13
Release date:2013-06-05
Last modified:2013-07-31
Method:X-RAY DIFFRACTION (2.4201 Å)
Cite:Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII).
J.Biol.Chem., 288, 2013
4KBQ
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STRUCTURE OF THE CHIP-TPR DOMAIN IN COMPLEX WITH THE HSC70 LID-TAIL DOMAINS
Descriptor:E3 ubiquitin-protein ligase CHIP, Heat shock cognate 71 kDa protein
Authors:Page, R.C., Amick, J., Nix, J.C., Misra, S.
Deposit date:2013-04-23
Release date:2015-01-14
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:A Bipartite Interaction between Hsp70 and CHIP Regulates Ubiquitination of Chaperoned Client Proteins.
Structure, 23, 2015
6CQS
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SEDIMINISPIROCHAETA SMARAGDINAE SPS-1 METALLO-BETA-LACTAMASE
Descriptor:Beta-lactamase, ZINC ION
Authors:Page, R.C., VanPelt, J., Cheng, Z., Crowder, M.W.
Deposit date:2018-03-16
Release date:2018-08-29
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Noncanonical Metal Center Drives the Activity of the Sediminispirochaeta smaragdinae Metallo-beta-lactamase SPS-1.
Biochemistry, 57, 2018
6NHK
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MORTALIN NUCLEOTIDE BINDING DOMAIN IN THE ADP-BOUND STATE
Descriptor:Stress-70 protein, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Page, R.C., Moseng, M.A., Nix, J.C.
Deposit date:2018-12-23
Release date:2019-04-17
Method:X-RAY DIFFRACTION (2.777 Å)
Cite:Biophysical Consequences of EVEN-PLUS Syndrome Mutations for the Function of Mortalin.
J Phys Chem B, 2019
2KNC
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PLATELET INTEGRIN ALFAIIB-BETA3 TRANSMEMBRANE-CYTOPLASMIC HETEROCOMPLEX
Descriptor:Integrin alpha-IIb, Integrin beta-3
Authors:Yang, J., Ma, Y., Page, R.C., Misra, S., Plow, E.F., Qin, J.
Deposit date:2009-08-20
Release date:2009-09-29
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.
Proc.Natl.Acad.Sci.USA, 106, 2009
3DWJ
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HEME-PROXIMAL W188H MUTANT OF INDUCIBLE NITRIC OXIDE SYNTHASE
Descriptor:Nitric oxide synthase, inducible, SULFATE ION, ...
Authors:Tejero, J., Biswas, A., Wang, Z.-Q., Haque, M.M., Hemann, C., Zweier, J.L., Page, R.C., Misra, S., Stuehr, D.J.
Deposit date:2008-07-22
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Stabilization and Characterization of a Heme-Oxy Reaction Intermediate in Inducible Nitric-oxide Synthase
J.Biol.Chem., 283, 2008
4JS9
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STRUCTURAL CHARACTERIZATION OF INDUCIBLE NITRIC OXIDE SYNTHASE SUBSTITUTED WITH MESOHEME
Descriptor:Nitric oxide synthase, inducible, Mesoheme, ...
Authors:Hannibal, L., Page, R.C., Bolisetty, K., Yu, Z., Misra, S., Stuehr, D.J.
Deposit date:2013-03-22
Release date:2014-04-23
Method:X-RAY DIFFRACTION (2.784 Å)
Cite:Kinetic and Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme
To be Published
4KBO
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CRYSTAL STRUCTURE OF THE HUMAN MORTALIN (GRP75) ATPASE DOMAIN IN THE APO FORM
Descriptor:Stress-70 protein, mitochondrial, SODIUM ION
Authors:Amick, J., Page, R.C., Nix, J.C., Misra, S.
Deposit date:2013-04-23
Release date:2014-04-02
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone.
Protein Sci., 23, 2014
4NQ2
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STRUCTURE OF ZN(II)-BOUND METALLO-BETA-LACTAMSE VIM-2 FROM PSEUDOMONAS AERUGINOSA
Descriptor:Beta-lactamase class B VIM-2, ZINC ION, ACETATE ION
Authors:Aitha, M., Nix, J.C., Crowder, M.W., Page, R.C.
Deposit date:2013-11-23
Release date:2014-11-12
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Biochemical, Mechanistic, and Spectroscopic Characterization of Metallo-beta-lactamase VIM-2.
Biochemistry, 53, 2014
5F14
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STRUCTURE OF NATIVE HEN EGG-WHITE LYSOZYME
Descriptor:Lysozyme C, SODIUM ION, CHLORIDE ION
Authors:McGlone, C., Nix, J.C., Page, R.C.
Deposit date:2015-11-30
Release date:2016-02-24
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.148 Å)
Cite:Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme-Polymer Conjugates.
Biomacromolecules, 17, 2016
5F16
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CTA-MODIFIED HEN EGG-WHITE LYSOZYME
Descriptor:Lysozyme C, SODIUM ION, CHLORIDE ION
Authors:McGlone, C., Nix, J.C., Page, R.C.
Deposit date:2015-11-30
Release date:2016-02-24
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme-Polymer Conjugates.
Biomacromolecules, 17, 2016
5WIG
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STRUCTURE OF NEW DELHI METALLO-BETA-LACTAMASE 4 (NDM-4)
Descriptor:NDM-4, ZINC ION
Authors:VanPelt, J., Williams, C., Page, R.C.
Deposit date:2017-07-19
Release date:2017-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Naturally-Occurring New Delhi Metallo-beta-Lactamase Variants Have Increased Antibiotic Resistance At Low Zinc Concentrations
To Be Published
5WIH
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STRUCTURE OF NEW DELHI METALLO-BETA-LACTAMASE 12 (NDM-12)
Descriptor:Metallo-beta-lactamase NDM-12, ZINC ION
Authors:VanPelt, J., Williams, C., Page, R.C.
Deposit date:2017-07-19
Release date:2017-10-18
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Naturally-Occurring New Delhi Metallo-beta-Lactamase Variants Have Increased Antibiotic Resistance At Low Zinc Concentrations
To Be Published
3ISW
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CRYSTAL STRUCTURE OF FILAMIN-A IMMUNOGLOBULIN-LIKE REPEAT 21 BOUND TO AN N-TERMINAL PEPTIDE OF CFTR
Descriptor:Filamin-A, Cystic fibrosis transmembrane conductance regulator
Authors:Xu, Z., Page, R., Qin, J., Ithychanda, S.S., Liu, J.M., Misra, S.
Deposit date:2009-08-27
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Biochemical basis of the interaction between cystic fibrosis transmembrane conductance regulator and immunoglobulin-like repeats of filamin.
J.Biol.Chem., 285, 2010
3CQX
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CHAPERONE COMPLEX
Descriptor:Heat shock cognate 71 kDa protein, BAG family molecular chaperone regulator 2, THIOCYANATE ION, ...
Authors:Xu, Z., Nix, J.C., Misra, S.
Deposit date:2008-04-03
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2
Nat.Struct.Mol.Biol., 15, 2008
3D0T
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STRUCTURE OF THE BNB DOMAIN OF THE HSP70 COCHAPERONE BAG2
Descriptor:BAG family molecular chaperone regulator 2
Authors:Xu, Z., Nix, J.C., Devlin, K., Misra, S.
Deposit date:2008-05-02
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2.
Nat.Struct.Mol.Biol., 15, 2008