8SUV

CHIP-TPR in complex with the C-terminus of CHIC2

Summary for 8SUV

• Entry DOI: 10.2210/pdb8suv/pdb
• Descriptor: E3 ubiquitin-protein ligase CHIP, Cysteine-rich hydrophobic domain-containing protein 2, SULFATE ION, ... (4 entities in total)
• Functional Keywords: e3 ubiquitin ligase, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 69767.29

Authors

Cupo, A.R.,McDermott, L.E.,DeSilva, A.R.,Callahan, M.,Nix, J.C.,Gestwicki, J.E.,Page, R.C. (deposition date: 2023-05-13, release date: 2024-03-20)

• Primary citation: Callahan, M.,Hodul, M.,Carroll, E.,Ravalin, M.,Nadel, C.,de Silva, A.,Cupo, A.,McDermott, L.,Nix, J.,Page, R.,Kao, A.,Gestwicki, J.; Interaction with the membrane-anchored protein CHIC2 constrains the ubiquitin ligase activity of CHIP; Biorxiv, 2023; DOI: 10.1101/2023.07.17.549407

Experimental method

X-RAY DIFFRACTION (1.63 Å)