6P2U

Structure of Mortalin-NBD with N6-propargyladenosine-5'-diphosphate

Summary for 6P2U

• Entry DOI: 10.2210/pdb6p2u/pdb
• Related: 4KBO 6NHK
• Descriptor: Stress-70 protein, mitochondrial, 9-{5-O-[(S)-hydroxy(phosphonooxy)phosphoryl]-alpha-D-ribofuranosyl}-N-(prop-2-yn-1-yl)-9H-purin-6-amine, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: inhibitor, complex, atpase, chaperone
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 42000.59

Authors

Moseng, M.A.,Page, R.C. (deposition date: 2019-05-22, release date: 2019-06-19, Last modification date: 2023-10-11)

• Primary citation: Moseng, M.A.,Nix, J.C.,Page, R.C.; 2- and N6-functionalized adenosine-5'-diphosphate analogs for the inhibition of mortalin.; Febs Lett., 593:2030-2039, 2019; PubMed: 31177526; DOI: 10.1002/1873-3468.13475

Experimental method

X-RAY DIFFRACTION (2 Å)