1TRO
 
 | | CRYSTAL STRUCTURE OF TRP REPRESSOR OPERATOR COMPLEX AT ATOMIC RESOLUTION | | Descriptor: | DNA (5'-D(*TP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*T P*AP*C)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN | | Authors: | Otwinowski, Z, Schevitz, R.W, Zhang, R.-G, Lawson, C.L, Joachimiak, A, Marmorstein, R, Luisi, B.F, Sigler, P.B. | | Deposit date: | 1992-08-30 | | Release date: | 1994-01-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of trp repressor/operator complex at atomic resolution.
Nature, 335, 1988
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1QZ4
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6ROA
 | | Crystal structure of V57G mutant of human cystatin C | | Descriptor: | Cystatin-C | | Authors: | Orlikowska, M, Behrendt, I, Borek, D, Otwinowski, Z, Skowron, P, Szymanska, A. | | Deposit date: | 2019-05-10 | | Release date: | 2019-08-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | NMR and crystallographic structural studies of the extremely stable monomeric variant of human cystatin C with single amino acid substitution.
Febs J., 287, 2020
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4YPI
 | | Structure of Ebola virus nucleoprotein N-terminal fragment bound to a peptide derived from Ebola VP35 | | Descriptor: | Nucleoprotein, Polymerase cofactor VP35 | | Authors: | Leung, D.W, Borek, D.M, Binning, J.M, Otwinowski, Z, Amarasinghe, G.K, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2015-03-13 | | Release date: | 2015-04-08 | | Last modified: | 2019-12-04 | | Method: | X-RAY DIFFRACTION (3.71 Å) | | Cite: | An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.
Cell Rep, 11, 2015
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1POB
 | | CRYSTAL STRUCTURE OF COBRA-VENOM PHOSPHOLIPASE A2 IN A COMPLEX WITH A TRANSITION-STATE ANALOGUE | | Descriptor: | 1-O-OCTYL-2-HEPTYLPHOSPHONYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CALCIUM ION, PHOSPHOLIPASE A2 | | Authors: | White, S.P, Scott, D.L, Otwinowski, Z, Sigler, P.B. | | Deposit date: | 1992-09-07 | | Release date: | 1993-10-31 | | Last modified: | 2019-08-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of cobra-venom phospholipase A2 in a complex with a transition-state analogue.
Science, 250, 1990
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1POA
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1POC
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5DLL
 | | Aminopeptidase N (pepN) from Francisella tularensis subsp. tularensis SCHU S4 | | Descriptor: | Aminopeptidase N, CHLORIDE ION, PHOSPHATE ION, ... | | Authors: | Borek, D, Raczynska, J, Dubrovska, I, Grimshaw, S, Minasov, G, Shuvalova, L, Kwon, K, Anderson, W.F, Otwinowski, Z, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2015-09-07 | | Release date: | 2015-09-16 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Aminopeptidase N (pepN) from Francisella tularensis subsp. tularensis SCHU S4
To Be Published
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5DO7
 | | Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8 | | Descriptor: | ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8 | | Authors: | Lee, J.-Y, Kinch, L.N, Borek, D.M, Urbatsch, I.L, Xie, X.-S, Grishin, N.V, Cohen, J.C, Otwinowski, Z, Hobbs, H.H, Rosenbaum, D.M. | | Deposit date: | 2015-09-10 | | Release date: | 2016-05-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.93 Å) | | Cite: | Crystal structure of the human sterol transporter ABCG5/ABCG8.
Nature, 533, 2016
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4X6Z
 | | Yeast 20S proteasome in complex with PR-VI modulator | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Rostankowski, R, Witkowska, J, Borek, D, Otwinowski, Z, Jankowska, E. | | Deposit date: | 2014-12-09 | | Release date: | 2015-12-23 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures revealed the common place of binding of low-molecular
mass activators with the 20S proteasome
To Be Published
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5IZM
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2FCJ
 | | Structure of small TOPRIM domain protein from Bacillus stearothermophilus. | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, SULFATE ION, ... | | Authors: | Rezacova, P, Chen, Y, Borek, D, Collart, F, Joachimiak, A, Otwinowski, Z, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2005-12-12 | | Release date: | 2006-01-24 | | Last modified: | 2012-10-24 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Crystal structure and putative function of small Toprim domain-containing protein from Bacillus stearothermophilus.
Proteins, 70, 2008
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6VRS
 | | Single particle reconstruction of glucose isomerase from Streptomyces rubiginosus based on data acquired in the presence of substantial aberrations | | Descriptor: | MANGANESE (II) ION, xylose isomerase | | Authors: | Bromberg, R, Guo, Y, Borek, D, Otwinowski, Z. | | Deposit date: | 2020-02-09 | | Release date: | 2020-02-19 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | High-resolution cryo-EM reconstructions in the presence of substantial aberrations
Iucrj, 7, 2020
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6VSC
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6VSA
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5T8V
 | | Chaetomium thermophilum cohesin loader SCC2, C-terminal fragment | | Descriptor: | CITRIC ACID, Putative uncharacterized protein | | Authors: | Tomchick, D.R, Yu, H, Kikuchi, S, Ouyang, Z, Borek, D, Otwinowski, Z. | | Deposit date: | 2016-09-08 | | Release date: | 2016-10-19 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.798 Å) | | Cite: | Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy.
Proc.Natl.Acad.Sci.USA, 113, 2016
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3L25
 | | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA | | Descriptor: | CHLORIDE ION, FORMIC ACID, GLYCEROL, ... | | Authors: | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | | Deposit date: | 2009-12-14 | | Release date: | 2010-01-26 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
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3L28
 | | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain K339A mutant | | Descriptor: | CHLORIDE ION, Polymerase cofactor VP35, SODIUM ION, ... | | Authors: | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | | Deposit date: | 2009-12-14 | | Release date: | 2010-01-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
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3L27
 | | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain R312A mutant | | Descriptor: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | | Deposit date: | 2009-12-14 | | Release date: | 2010-01-26 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
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3L26
 | | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Polymerase cofactor VP35, ... | | Authors: | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | | Deposit date: | 2009-12-14 | | Release date: | 2010-01-26 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
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7U5T
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7U5U
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7U5S
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1HR8
 | | Yeast Mitochondrial Processing Peptidase beta-E73Q Mutant Complexed with Cytochrome C Oxidase IV Signal Peptide | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CYTOCHROME C OXIDASE POLYPEPTIDE IV, MITOCHONDRIAL PROCESSING PEPTIDASE ALPHA SUBUNIT, ... | | Authors: | Taylor, A.B, Smith, B.S, Kitada, S, Kojima, K, Miyaura, H, Otwinowski, Z, Ito, A, Deisenhofer, J. | | Deposit date: | 2000-12-21 | | Release date: | 2001-07-11 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences.
Structure, 9, 2001
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1GRL
 | | THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS | | Descriptor: | GROEL (HSP60 CLASS) | | Authors: | Braig, K, Otwinowski, Z, Hegde, R, Boisvert, D.C, Joachimiak, A, Horwich, A.L, Sigler, P.B. | | Deposit date: | 1995-03-07 | | Release date: | 1995-10-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The crystal structure of the bacterial chaperonin GroEL at 2.8 A.
Nature, 371, 1994
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