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2WIT
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BU of 2wit by Molmil
CRYSTAL STRUCTURE OF THE SODIUM-COUPLED GLYCINE BETAINE SYMPORTER BETP FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND SUBSTRATE
Descriptor: GLYCINE BETAINE TRANSPORTER BETP, TRIMETHYL GLYCINE
Authors:Ressl, S, Terwisscha Van Scheltinga, A.C, Vonrhein, C, Ott, V, Ziegler, C.
Deposit date:2009-05-17
Release date:2009-05-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Molecular Basis of Transport and Regulation in the Na(+)/Betaine Symporter Betp.
Nature, 458, 2009
2BOX
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BU of 2box by Molmil
EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with strontium.
Descriptor: CACODYLATE ION, CHLORIDE ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR, ...
Authors:Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
Deposit date:2005-04-14
Release date:2006-10-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BO2
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BU of 2bo2 by Molmil
EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with calcium.
Descriptor: CACODYLATE ION, CALCIUM ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR
Authors:Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
Deposit date:2005-04-07
Release date:2006-08-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BOU
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BU of 2bou by Molmil
EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with barium.
Descriptor: BARIUM ION, CACODYLATE ION, CALCIUM ION, ...
Authors:Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M.
Deposit date:2005-04-14
Release date:2006-10-18
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
1JNJ
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BU of 1jnj by Molmil
NMR solution structure of the human beta2-microglobulin
Descriptor: beta2-microglobulin
Authors:Verdone, G, Corazza, A, Viglino, P, Pettirossi, F, Giorgetti, S, Mangione, P, Andreola, A, Stoppini, M, Bellotti, V, Esposito, G.
Deposit date:2001-07-24
Release date:2002-02-27
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:The solution structure of human beta2-microglobulin reveals the prodromes of its amyloid transition.
Protein Sci., 11, 2002
1TOZ
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BU of 1toz by Molmil
NMR structure of the human NOTCH-1 ligand binding region
Descriptor: Neurogenic locus notch homolog protein 1
Authors:Hambleton, S, Valeyev, N.Y, Muranyi, A, Knott, V, Werner, J.M, Mcmichael, A.J, Handford, P.A, Downing, A.K.
Deposit date:2004-06-15
Release date:2004-10-12
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Structural and functional properties of the human notch-1 ligand binding region
STRUCTURE, 12, 2004
1APJ
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BU of 1apj by Molmil
NMR STUDY OF THE TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN-LIKE DOMAIN (TB MODULE/8-CYS DOMAIN), NMR, 21 STRUCTURES
Descriptor: FIBRILLIN
Authors:Yuan, X, Downing, A.K, Knott, V, Handford, P.A.
Deposit date:1997-07-22
Release date:1998-01-28
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Solution structure of the transforming growth factor beta-binding protein-like module, a domain associated with matrix fibrils.
EMBO J., 16, 1997
2Z9T
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BU of 2z9t by Molmil
Crystal structure of the human beta-2 microglobulin mutant W60G
Descriptor: Beta-2-microglobulin
Authors:Ricagno, S, Bolognesi, M, Bellotti, V, Corazza, A, Rennella, E, Gural, D, Mimmi, M.C, Betto, E, Pucillo, C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M.
Deposit date:2007-09-26
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties
J.Mol.Biol., 378, 2008
4FXL
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BU of 4fxl by Molmil
Crystal structure of the D76N Beta-2 Microglobulin mutant
Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Ricagno, S, Bellotti, V, Pepys, M.B, Stoppini, M, Bolognesi, M.
Deposit date:2012-07-03
Release date:2012-08-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Hereditary systemic amyloidosis due to Asp76Asn variant beta-2-microglobulin.
N.Engl.J.Med., 366, 2012
1PVF
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BU of 1pvf by Molmil
E.coli IPP isomerase in complex with diphosphate
Descriptor: DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, MAGNESIUM ION, ...
Authors:Wouters, J, Durisotti, V, Oudjama, Y, Stalon, V, Droogmans, L.
Deposit date:2003-06-27
Release date:2004-07-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:E.coli Isopentenyl Diphosphate: Dimethylallyl Diphosphate isomerase in complex with diphosphate
To be Published
1EDM
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BU of 1edm by Molmil
EPIDERMAL GROWTH FACTOR-LIKE DOMAIN FROM HUMAN FACTOR IX
Descriptor: CALCIUM ION, FACTOR IX
Authors:Rao, Z, Handford, P, Mayhew, M, Knott, V, Brownlee, G.G, Stuart, D.
Deposit date:1996-03-21
Release date:1996-10-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structure of a Ca(2+)-binding epidermal growth factor-like domain: its role in protein-protein interactions.
Cell(Cambridge,Mass.), 82, 1995
1PY4
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BU of 1py4 by Molmil
Beta2 microglobulin mutant H31Y displays hints for amyloid formations
Descriptor: Beta-2-microglobulin precursor
Authors:Rosano, C, Zuccotti, S, Mangione, P, Giorgetti, S, Bellotti, V, Pettirossi, F, Corazza, A, Viglino, P, Esposito, G, Bolognesi, M.
Deposit date:2003-07-08
Release date:2004-05-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation
J.Mol.Biol., 335, 2004
2X89
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BU of 2x89 by Molmil
Structure of the Beta2_microglobulin involved in amyloidogenesis
Descriptor: ANTIBODY, BETA-2-MICROGLOBULIN
Authors:Domanska, K, Srinivasan, V, Vanderhaegen, S, Pardon, E, Marquez, J.A, Bellotti, V, Wyns, L, Steyaert, J.
Deposit date:2010-03-07
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Atomic Structure of a Nanobody-Trapped Domain-Swapped Dimer of an Amyloidogenic {Beta}2-Microglobulin Variant.
Proc.Natl.Acad.Sci.USA, 108, 2011
3DHM
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BU of 3dhm by Molmil
Beta 2 microglobulin mutant D59P
Descriptor: Beta-2-microglobulin
Authors:Ricagno, S, Colombo, M, de Rosa, M, Bolognesi, M, Giorgetti, S, Bellotti, V.
Deposit date:2008-06-18
Release date:2008-11-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:DE loop mutations affect beta2-microglobulin stability and amyloid aggregation
Biochem.Biophys.Res.Commun., 377, 2008
3EKC
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BU of 3ekc by Molmil
structure of W60V beta-2 microglobulin mutant
Descriptor: Beta-2-microglobulin
Authors:Ricagno, S, Sangiovanni, E, Bellotti, V, Bolognesi, M.
Deposit date:2008-09-19
Release date:2009-05-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human beta-2 microglobulin W60V mutant structure: Implications for stability and amyloid aggregation
Biochem.Biophys.Res.Commun., 380, 2009
3DHJ
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BU of 3dhj by Molmil
Beta 2 microglobulin mutant W60C
Descriptor: Beta-2-microglobulin
Authors:Ricagno, S, Colombo, M, de Rosa, M, Bolognesi, M, Giorgetti, S, Bellotti, V.
Deposit date:2008-06-18
Release date:2008-11-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:DE loop mutations affect beta2-microglobulin stability and amyloid aggregation
Biochem.Biophys.Res.Commun., 377, 2008
1UZK
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BU of 1uzk by Molmil
Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Ca bound to cbEGF23 domain only
Descriptor: CALCIUM ION, FIBRILLIN-1
Authors:Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I.
Deposit date:2004-03-13
Release date:2006-05-24
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1UZP
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BU of 1uzp by Molmil
Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Sm bound form cbEGF23 domain only.
Descriptor: FIBRILLIN-1, SAMARIUM (III) ION
Authors:Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I.
Deposit date:2004-03-15
Release date:2004-04-08
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1UZJ
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BU of 1uzj by Molmil
Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, holo form.
Descriptor: CALCIUM ION, FIBRILLIN-1
Authors:Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I.
Deposit date:2004-03-12
Release date:2004-04-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1UZQ
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BU of 1uzq by Molmil
Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, apo form cbEGF23 domain only.
Descriptor: FIBRILLIN-1
Authors:Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I.
Deposit date:2004-03-15
Release date:2004-04-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1KSQ
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BU of 1ksq by Molmil
NMR Study of the Third TB Domain from Latent Transforming Growth Factor-beta Binding Protein-1
Descriptor: LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN 1
Authors:Lack, J, O'leary, J.M, Knott, V, Yuan, X, Rifkin, D.B, Handford, P.A, Downing, A.K.
Deposit date:2002-01-14
Release date:2003-08-26
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Solution Structure of the Third TB Domain from LTBP1 Provides Insight into Assembly of the Large Latent Complex that Sequesters Latent TGF-beta.
J.Mol.Biol., 334, 2003
4MMO
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BU of 4mmo by Molmil
The crystal structure of a M20 family metallo-carboxypeptidase Sso-CP2 from Sulfolobus solfataricus
Descriptor: GLYCEROL, SULFATE ION, Sso-CP2 metallo-carboxypetidase, ...
Authors:Dupuy, J, Dutoit, R, Durisotti, V, Demarez, M, Borel, F, Van Elder, D, Legrain, C, Bauvois, C.
Deposit date:2013-09-09
Release date:2014-10-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3363 Å)
Cite:Biochemical characterization of a novel thermostable dinuclear carboxypeptidase from the thermoacidophilic archaeum Sulfolobus solfataricus.
To be Published
4L3C
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BU of 4l3c by Molmil
Structure of HLA-A2 in complex with D76N b2m mutant and NY-ESO1 double mutant
Descriptor: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
Authors:Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
Deposit date:2013-06-05
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
4L29
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BU of 4l29 by Molmil
Structure of wtMHC class I with NY-ESO1 double mutant
Descriptor: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
Authors:Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
Deposit date:2013-06-04
Release date:2013-12-25
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
1P0A
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BU of 1p0a by Molmil
NMR structure of ETD135, mutant of the antifungal defensin ARD1 from Archaeoprepona demophon
Descriptor: DEFENSIN ARD1
Authors:Landon, C, Guenneugues, M, Barbault, F, Legrain, M, Menin, L, Schott, V, Vovelle, F, Dimarcq, J.L.
Deposit date:2003-04-10
Release date:2004-03-09
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Lead optimization of antifungal peptides with 3D NMR structures analysis.
Protein Sci., 13, 2004

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