Author results

1N96
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DIMERIC SOLUTION STRUCTURE OF THE CYCLIC OCTAMER CD(CGCTCATT)
Descriptor:CYCLIC OLIGONUCLEOTIDE D(CGCTCATT)
Authors:Escaja, N., Gelpi, J.L., Orozco, M., Rico, M., Pedroso, E., Gonzalez, C.
Deposit date:2002-11-22
Release date:2003-05-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Four-stranded DNA structure stabilized by a novel G:C:A:T tetrad.
J.Am.Chem.Soc., 125, 2003
2KP3
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STRUCTURE OF ANA-RNA HYBRID DUPLEX
Descriptor:RNA (5'-R(*(GAO)P*(CAR)P*(UAR)P*(A5O)P*(UAR)P*(A5O)P*(A5O)P*(UAR)P*(GAO)P*(GAO))-3'), RNA (5'-R(*CP*CP*AP*UP*UP*AP*UP*AP*GP*C)-3')
Authors:Gonzalez, C., Martn-Pintado, N., Watts, J., Gomez-Pinto, I., Dhama, M., Orozco, M., Schwartzentruber, J., Portella, G.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility.
Nucleic Acids Res., 38, 2010
2KP4
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STRUCTURE OF 2'F-ANA/RNA HYBRID DUPLEX
Descriptor:DNA (5'-D(*(GFL)P*(CFL)P*(TAF)P*(A5L)P*(TAF)P*(A5L)P*(A5L)P*(TAF)P*(GFL)P*(GFL))-3'), RNA (5'-R(*CP*CP*AP*UP*UP*AP*UP*AP*GP*C)-3')
Authors:Gonzalez, C., Martin-Pintado, N., Watts, J., Gomez-Pinto, I., Dhama, M., Orozco, M., Schwartzentruber, J., Portella, G.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility.
Nucleic Acids Res., 38, 2010
2M1G
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PARALLEL HUMAN TELOMERIC QUADRUPLEX CONTAINING 2'F-ANA SUBSTITUTIONS
Descriptor:5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(GFL)P*GP*GP*T)-3'
Authors:Martin-Pintado, N., Yahyaee-Anzahaee, M., Deleavey, G.F., Portella, G., Orozco, M., Damha, M.J., Gonzalez, C.
Deposit date:2012-11-27
Release date:2013-05-08
Method:SOLUTION NMR
Cite:Dramatic effect of furanose c2' substitution on structure and stability: directing the folding of the human telomeric quadruplex with a single fluorine atom.
J.Am.Chem.Soc., 135, 2013
2M84
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STRUCTURE OF 2'F-RNA/2'F-ANA CHIMERIC DUPLEX
Descriptor:2'F-RNA/2'F-ANA CHIMERIC DUPLEX
Authors:Martin-Pintado, N., Deleavey, G., Portella, G., Campos, R., Orozco, M., Damha, M., Gonzalez, C.
Deposit date:2013-05-07
Release date:2013-11-27
Last modified:2014-05-21
Method:SOLUTION NMR
Cite:Backbone FCHO Hydrogen Bonds in 2'F-Substituted Nucleic Acids.
Angew.Chem.Int.Ed.Engl., 52, 2013
2M8A
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2'F-ANA/2'F-RNA ALTERNATED SEQUENCES
Descriptor:2'F-RNA/2'F-ANA chimeric duplex
Authors:Martin-Pintado, N., Deleavey, G., Portella, G., Campos, R., Orozco, M., Damha, M., Gonzalez, C.
Deposit date:2013-05-14
Release date:2013-11-27
Last modified:2014-05-21
Method:SOLUTION NMR
Cite:Backbone FCHO Hydrogen Bonds in 2'F-Substituted Nucleic Acids.
Angew.Chem.Int.Ed.Engl., 52, 2013
5M3D
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STRUCTURAL TUNING OF CD81LEL (SPACE GROUP P31)
Descriptor:CD81 antigen, 1,2-ETHANEDIOL, PHOSPHATE ION
Authors:Cunha, E.S., Sfriso, P., Rojas, A.L., Roversi, P., Hospital, A., Orozco, M., Abrescia, N.G.
Deposit date:2016-10-14
Release date:2016-12-14
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
5M3T
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STRUCTURAL TUNING OF CD81LEL (SPACE GROUP P64)
Descriptor:CD81 antigen, CHLORIDE ION, 1,2-ETHANEDIOL
Authors:Cunha, E.S., Sfriso, P., Rojas, A.L., Roversi, P., Hospital, A., Orozco, M., Abrescia, N.G.
Deposit date:2016-10-17
Release date:2016-12-14
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.021 Å)
Cite:Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
5M4R
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STRUCTURAL TUNING OF CD81LEL (SPACE GROUP C2)
Descriptor:CD81 antigen, SULFATE ION, 1,2-ETHANEDIOL
Authors:Cunha, E.S., Sfriso, P., Rojas, A.L., Roversi, P., Hospital, A., Orozco, M., Abrescia, N.G.
Deposit date:2016-10-19
Release date:2016-12-14
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
5N5C
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NMR SOLUTION STRUCTURE OF THE TSL2 RNA HAIRPIN
Descriptor:RNA (19-MER)
Authors:Garcia-Lopez, A., Wacker, A., Tessaro, F., Jonker, H.R.A., Richter, C., Comte, A., Berntenis, N., Schmucki, R., Hatje, K., Sciarra, D., Konieczny, P., Fournet, G., Faustino, I., Orozco, M., Artero, R., Goekjian, P., Metzger, F., Ebeling, M., Joseph, B., Schwalbe, H., Scapozza, L.
Deposit date:2017-02-13
Release date:2018-03-14
Last modified:2018-06-06
Method:SOLUTION NMR
Cite:Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes.
Nat Commun, 9, 2018
1IEK
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SOLUTION STRUCTURE OF THE DNA DUPLEX D(CCACCGGAAC).(GTTCCGGTGG) WITH A CHIRAL ALKYL-PHOSPHONATE MOIETY (DIAESTEREOISOMER S)
Descriptor:5'-D(*CP*CP*AP*CP*CP*(OCT)GP*GP*AP*AP*C)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*TP*GP*G)-3', N-OCTANE
Authors:Soliva, R., Monaco, V., Gomez-Pinto, I., Meeuwenoord, N.J., van der Marel, G.A., van Boom, J.H., Gonzalez, C., Orozco, M.
Deposit date:2001-04-10
Release date:2001-07-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a DNA duplex with a chiral alkyl phosphonate moiety.
Nucleic Acids Res., 29, 2001
1IEY
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SOLUTION STRUCTURE OF THE DNA DUPLEX D(CCACCGGAAC).(GTTCCGGTGG) WITH A CHIRAL ALKYL-PHOSPHONATE MOIETY (DIAESTEREOISOMER R)
Descriptor:5'-D(P*CP*CP*AP*CP*CP*(OCT)GP*GP*AP*AP*C)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*TP*GP*G)-3', N-OCTANE
Authors:Soliva, R., Monaco, V., Gomez-Pinto, I., Meeuwenoord, N.J., van der Marel, G.A., van Boom, J.H., Gonzalez, C., Orozco, M.
Deposit date:2001-04-11
Release date:2001-07-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a DNA duplex with a chiral alkyl phosphonate moiety.
Nucleic Acids Res., 29, 2001
1SP6
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A DNA DUPLEX CONTAINING A CHOLESTEROL ADDUCT (ALPHA-ANOMER)
Descriptor:5'-D(*CP*CP*AP*CP*(HOL)P*GP*GP*AP*AP*C)-3', 5'-D(GP*TP*TP*CP*CP*GP*GP*TP*GP*G)-3'
Authors:Gomez-Pinto, I., Cubero, E., Kalko, S.G., Monaco, V., van der Marel, G., van Boom, J.H., Orozco, M., Gonzalez, C.
Deposit date:2004-03-16
Release date:2004-06-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Effect of bulky lesions on DNA: Solution structure of a DNA duplex containing a cholesterol adduct.
J.Biol.Chem., 279, 2004
1SSJ
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A DNA DUPLEX CONTAINING A CHOLESTEROL ADDUCT (BETA-ANOMER)
Descriptor:5'-D(*CP*CP*AP*CP*(HOB)P*GP*GP*AP*AP*C)-3', 5'-D(GP*TP*TP*CP*CP*GP*GP*TP*GP*G)-3'
Authors:Gomez-Pinto, I., Cubero, E., Kalko, S.G., Monaco, V., van der Marel, G., van Boom, J.H., Orozco, M., Gonzalez, C.
Deposit date:2004-03-24
Release date:2004-06-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Effect of bulky lesions on DNA: Solution structure of a DNA duplex containing a cholesterol adduct.
J.Biol.Chem., 279, 2004
4D6N
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 10 DAYS INCUBATION IN 5MM MG (STATE 7)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*DGP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*DAP)-3', 5'-D(*DGP*TP*TP*CP*CP*GP*GP*CP*GP*CP*GP)-3', ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-11-13
Release date:2014-12-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4D6O
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MG (STATE 2)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 25MER, MAGNESIUM ION, ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-11-13
Release date:2014-12-17
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UN7
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA BEFORE INCUBATION IN 5MM MN (STATE 1)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 25MER, ZINC ION
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-03
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UN8
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MN (STATE 2)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 25MER, MANGANESE (II) ION
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UN9
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 8H INCUBATION IN 5MM MN (STATE 3)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 25MER, MANGANESE (II) ION
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2015-01-14
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (2.734 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UNA
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 2 DAYS INCUBATION IN 5MM MN (STATE 4)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 25MER, 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UNB
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 6 DAYS INCUBATION IN 5MM MN (STATE 5)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*A)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UNC
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 8 DAYS INCUBATION IN 5MM MN (STATE 6)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*A)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UT0
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THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 10 DAYS INCUBATION IN 5MM MN (STATE 7)
Descriptor:HOMING ENDONUCLEASE I-DMOI, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*GP)-3', ...
Authors:Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M.J., Orozco, M., Prieto, J., Montoya, G.
Deposit date:2014-07-17
Release date:2014-12-17
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
5M2C
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STRUCTURAL TUNING OF CD81LEL (SPACE GROUP P32 1 2)
Descriptor:CD81 antigen, PHOSPHATE ION
Authors:Cunha, E.S., Sfriso, P., Rojas, A.L., Roversi, P., Hospital, A., Orozco, M., Abrescia, N.G.
Deposit date:2016-10-12
Release date:2016-12-14
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.961 Å)
Cite:Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
5M33
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STRUCTURAL TUNING OF CD81LEL (SPACE GROUP P21)
Descriptor:CD81 antigen, 1,2-ETHANEDIOL
Authors:Cunha, E.S., Sfriso, P., Rojas, A.L., Roversi, P., Hospital, A., Orozco, M., Abrescia, N.G.
Deposit date:2016-10-14
Release date:2016-12-14
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
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