8OFC

Structure of an i-motif domain with the cytosine analog 1,3-diaza-2-oxophenoxacione (tC) at neutral pH

Summary for 8OFC

• Entry DOI: 10.2210/pdb8ofc/pdb
• NMR Information: BMRB: 34798
• Descriptor: DNA (5'-D(*CP*(YCO)P*GP*TP*TP*CP*(DNR)P*GP*TP*TP*TP*TP*TP*CP*CP*GP*TP*TP*CP*(DNR)P*GP*T)-3') (1 entity in total)
• Functional Keywords: i-motif, fluorescent, non-canonical dna, dna
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 6719.34

Authors

Mir, B.,Serrano-Chacon, I.,Terrazas, M.,Gandioso, A.,Garavis, M.,Orozco, M.,Escaja, N.,Gonzalez, C. (deposition date: 2023-03-15, release date: 2024-02-07, Last modification date: 2024-04-24)

• Primary citation: Mir, B.,Serrano-Chacon, I.,Medina, P.,Macaluso, V.,Terrazas, M.,Gandioso, A.,Garavis, M.,Orozco, M.,Escaja, N.,Gonzalez, C.; Site-specific incorporation of a fluorescent nucleobase analog enhances i-motif stability and allows monitoring of i-motif folding inside cells.; Nucleic Acids Res., 52:3375-3389, 2024; PubMed: 38366792; DOI: 10.1093/nar/gkae106

Experimental method

SOLUTION NMR