Author results

1BBU
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LYSYL-TRNA SYNTHETASE (LYSS) COMPLEXED WITH LYSINE
Descriptor:PROTEIN (LYSYL-TRNA SYNTHETASE), LYSINE
Authors:Onesti, S., Desogus, G., Brevet, A., Chen, J., Plateau, P., Blanquet, S., Brick, P.
Deposit date:1998-04-24
Release date:2000-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
1BBW
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LYSYL-TRNA SYNTHETASE (LYSS)
Descriptor:PROTEIN (LYSYL-TRNA SYNTHETASE)
Authors:Onesti, S., Desogus, G., Brevet, A., Chen, J., Plateau, P., Blanquet, S., Brick, P.
Deposit date:1998-04-24
Release date:2000-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
1LYL
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LYSYL-TRNA SYNTHETASE (LYSU) (E.C.6.1.1.6) COMPLEXED WITH LYSINE
Descriptor:LYSYL-TRNA SYNTHETASE (LYSU), LYSINE
Authors:Onesti, S., Brick, P.
Deposit date:1995-05-03
Release date:1995-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli
Structure, 3, 1995
1TIE
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CRYSTAL STRUCTURE OF A KUNITZ-TYPE TRYPSIN INHIBITOR FROM ERYTHRINA CAFFRA SEEDS
Descriptor:ERYTHRINA TRYPSIN INHIBITOR
Authors:Onesti, S., Brick, P., Blow, D.M.
Deposit date:1991-02-14
Release date:1992-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a Kunitz-type trypsin inhibitor from Erythrina caffra seeds.
J.Mol.Biol., 217, 1991
6EHT
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MODULATION OF PCNA SLIDING SURFACE BY P15PAF SUGGESTS A SUPPRESSIVE MECHANISM FOR CISPLATIN-INDUCED DNA LESION BYPASS BY POL ETA HOLOENZYME
Descriptor:Proliferating cell nuclear antigen, PCNA-associated factor, DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), ...
Authors:De March, M., Barrera-Vilarmau, S., Mentegari, E., Merino, N., Bressan, E., Maga, G., Crehuet, R., Onesti, S., Blanco, F.J., De Biasio, A.
Deposit date:2017-09-15
Release date:2018-08-08
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
1BA7
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SOYBEAN TRYPSIN INHIBITOR
Descriptor:TRYPSIN INHIBITOR (KUNITZ)
Authors:De Meester, P., Brick, P., Lloyd, L.F., Blow, D.M., Onesti, S.
Deposit date:1998-04-22
Release date:1998-06-17
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Kunitz-type soybean trypsin inhibitor (STI): implication for the interactions between members of the STI family and tissue-plasminogen activator.
Acta Crystallogr.,Sect.D, 54, 1998
1MBA
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APLYSIA LIMACINA MYOGLOBIN. CRYSTALLOGRAPHIC ANALYSIS AT 1.6 ANGSTROMS RESOLUTION
Descriptor:MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bolognesi, M., Onesti, S., Gatti, G., Coda, A., Ascenzi, P., Brunori, M.
Deposit date:1989-02-22
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Aplysia limacina myoglobin. Crystallographic analysis at 1.6 A resolution.
J.Mol.Biol., 205, 1989
3MBA
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APLYSIA LIMACINA MYOGLOBIN. CRYSTALLOGRAPHIC ANALYSIS AT 1.6 ANGSTROMS RESOLUTION
Descriptor:MYOGLOBIN, FLUORIDE ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bolognesi, M., Onesti, S., Gatti, G., Coda, A., Ascenzi, P., Brunori, M.
Deposit date:1989-02-22
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Aplysia limacina myoglobin. Crystallographic analysis at 1.6 A resolution.
J.Mol.Biol., 205, 1989
4MBA
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APLYSIA LIMACINA MYOGLOBIN. CRYSTALLOGRAPHIC ANALYSIS AT 1.6 ANGSTROMS RESOLUTION
Descriptor:MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, IMIDAZOLE
Authors:Bolognesi, M., Onesti, S., Gatti, G., Coda, A., Ascenzi, P., Brunori, M.
Deposit date:1989-02-22
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Aplysia limacina myoglobin. Crystallographic analysis at 1.6 A resolution.
J.Mol.Biol., 205, 1989
6GIS
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STRUCTURAL BASIS OF HUMAN CLAMP SLIDING ON DNA
Descriptor:Proliferating cell nuclear antigen, DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3')
Authors:De March, M., Merino, N., Barrera-Vilarmau, S., Crehuet, R., Onesti, S., Blanco, F.J., De Biasio, A.
Deposit date:2018-05-15
Release date:2018-05-30
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural basis of human PCNA sliding on DNA.
Nat Commun, 8, 2017
1DZF
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RPB5 FROM S.CEREVISIAE
Descriptor:DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1
Authors:Todone, F., Weinzierl, R.O.J., Brick, P., Onesti, S.
Deposit date:2000-02-25
Release date:2000-06-09
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Rpb5, a Universal Eukaryotic RNA Polymerase Subunit and Trascription Factor Interaction Target
Proc.Natl.Acad.Sci.USA, 97, 2000
1E1O
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM, COMPLEXED WITH LYSINE
Descriptor:LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE, LYSINE, ...
Authors:Desogus, G., Todone, F., Brick, P., Onesti, S.
Deposit date:2000-05-09
Release date:2000-07-28
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1E1T
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM COMPLEXED WITH THE LYSYL_ADENYLATE INTERMEDIATE
Descriptor:LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE, ADENOSINE-5'-[LYSYL-PHOSPHATE], ...
Authors:Desogus, G., Todone, F., Brick, P., Onesti, S.
Deposit date:2000-05-10
Release date:2000-07-28
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1E22
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM COMPLEXED WITH LYSINE AND THE NON-HYDROLYSABLE ATP ANALOGUE AMP-PCP
Descriptor:LYSYL-TRNA SYNTHETASE, LYSINE, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Desogus, G., Todone, F., Brick, P., Onesti, S.
Deposit date:2000-05-15
Release date:2000-07-28
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1E24
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM COMPLEXED WITH LYSINE AND ATP AND MN2+
Descriptor:LYSYL-TRNA SYNTHETASE, LYSINE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Desogus, G., Todone, F., Brick, P., Onesti, S.
Deposit date:2000-05-16
Release date:2000-07-28
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1GO3
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STRUCTURE OF AN ARCHEAL HOMOLOG OF THE EUKARYOTIC RNA POLYMERASE II RPB4/RPB7 COMPLEX
Descriptor:DNA-DIRECTED RNA POLYMERASE SUBUNIT E, DNA-DIRECTED RNA POLYMERASE SUBUNIT F
Authors:Todone, F., Brick, P., Werner, F., Weinzierl, R.O.J., Onesti, S.
Deposit date:2001-10-17
Release date:2001-12-07
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of an Archaeal Homolog of the Eukaryotic RNA Polymerase II Rpb4/Rpb7 Complex
Mol.Cell, 8, 2001
2C35
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SUBUNITS RPB4 AND RPB7 OF HUMAN RNA POLYMERASE II
Descriptor:DNA-DIRECTED RNA POLYMERASE II 16 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KDA POLYPEPTIDE
Authors:Meka, H., Werner, F., Cordell, S.C., Onesti, S., Brick, P.
Deposit date:2005-10-04
Release date:2005-11-18
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure and RNA Binding of the Rpb4/Rpb7 Subunits of Human RNA Polymerase II.
Nucleic Acids Res., 33, 2005
2MPJ
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NMR STRUCTURE OF XENOPUS RECQ4 ZINC KNUCKLE
Descriptor:RECQL4-helicase-like protein, ZINC ION
Authors:Zucchelli, C., Marino, F., Mojumdar, A., Onesti, S., Musco, G.
Deposit date:2014-05-23
Release date:2015-08-05
Last modified:2016-03-09
Method:SOLUTION NMR
Cite:Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases
Sci Rep, 6, 2016
4R50
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-ETPP MUTANT COCRYSTALLIZED WITH LI+
Descriptor:Potassium channel protein, (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-08-20
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
4R6Z
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK MUTANT, NAK-ETPP, CS+ COMPLEX
Descriptor:Potassium channel protein, CESIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-08-26
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
4R7C
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-ETPP MUTANT COCRYSTALLIZED WITH DIMETHYLAMMONIUM
Descriptor:Potassium channel protein, GLYCINE, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-08-27
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
4R8C
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-ETPP MUTANT IN COMPLEX WITH RB+
Descriptor:Potassium channel protein, RUBIDIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-09-01
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
4RAI
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-ETPP MUTANT IN COMPLEX WITH NA+
Descriptor:Potassium channel protein, SODIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-09-10
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
4RO2
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-ETPP MUTANT COCRYSTALLIZED WITH METHYLAMMONIUM
Descriptor:Potassium channel protein, methylammonium ion, GLYCINE, ...
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-10-27
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
6FIZ
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-EAPP MUTANT (T67A) COCRYSTALLIZED WITH K+
Descriptor:CNG mimic T67A mutant monomer, GLYCINE, POTASSIUM ION, ...
Authors:Napolitano, L.M.R., De March, M., Steiner, A.R., Onesti, S.
Deposit date:2018-01-19
Release date:2019-03-06
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Crystal Structure of CNG mimicking NaK-EAPP mutant (T67A) cocrystallized with K+
To Be Published
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