4R6Z

Crystal Structure of CNG mimicking NaK mutant, NaK-ETPP, Cs+ complex

Summary for 4R6Z

• Entry DOI: 10.2210/pdb4r6z/pdb
• Related: 3K0D 3K0G 4R50
• Descriptor: Potassium channel protein, CESIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
• Functional Keywords: alpha-helical membrane protein, chimera channel, transport protein
• Biological source: Bacillus cereus ATCC 14579
• Total number of polymer chains: 2
• Total formula weight: 23054.79

Authors

De March, M.,Napolitano, L.M.R.,Onesti, S. (deposition date: 2014-08-26, release date: 2015-07-01, Last modification date: 2023-09-20)

• Primary citation: Napolitano, L.M.,Bisha, I.,De March, M.,Marchesi, A.,Arcangeletti, M.,Demitri, N.,Mazzolini, M.,Rodriguez, A.,Magistrato, A.,Onesti, S.,Laio, A.,Torre, V.; A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.; Proc.Natl.Acad.Sci.USA, 112:E3619-E3628, 2015; PubMed: 26100907; DOI: 10.1073/pnas.1503334112

Experimental method

X-RAY DIFFRACTION (2.3 Å)