4V4K
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3LJ5
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8VUE
| L5A7 Fab bound to Indonesia2005 Hemagglutinin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | Authors: | Olia, A.S, Gorman, J, Kwong, P.D. | Deposit date: | 2024-01-29 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody. Front Immunol, 15, 2024
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8VUZ
| L5A7 Fab bound to 28H6E11 anti-idiotype Fab | Descriptor: | 28H6E11 Fab Heavy Chain, 28H6E11 Fab Light Chain, L5A7 Fab Heavy Chain, ... | Authors: | Olia, A.S, Morano, N.C, Kwong, P.D. | Deposit date: | 2024-01-30 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody. Front Immunol, 15, 2024
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2POH
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8F7T
| Glycan-Base ConC Env Trimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env gp120, ... | Authors: | Olia, A.S, Kwong, P.D. | Deposit date: | 2022-11-20 | Release date: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Soluble prefusion-closed HIV-envelope trimers with glycan-covered bases. Iscience, 26, 2023
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8TDX
| TRNM-b.01 in complex with HIV Env fusion peptide | Descriptor: | Env Fusion Peptide, TRNM-b.01 Fab Heavy Chain, TRNM-b.01 Fab Light Chain | Authors: | Olia, A.S, Kwong, P.D. | Deposit date: | 2023-07-05 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques To Be Published
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8VVB
| Influenza antibody L5A7 Fab | Descriptor: | L5A7 Heavy Chain, L5A7 Light Chain | Authors: | Harris, D.R, Olia, A.S, Kwong, P.D. | Deposit date: | 2024-01-30 | Release date: | 2024-05-22 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody. Front Immunol, 15, 2024
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3C9I
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8F7Z
| VRC34.01_mm28 bound to fusion peptide | Descriptor: | HIV-1 Env Fusion Peptide, VRC34_m228 Light Chain, VRC34_mm28 Heavy Chain | Authors: | Olia, A.S, Kwong, P.D. | Deposit date: | 2022-11-21 | Release date: | 2023-11-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site. Nat Commun, 14, 2023
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7MTD
| Structure of aged SARS-CoV-2 S2P spike at pH 7.4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Tsybovsky, Y, Olia, A.S, Kwong, P.D. | Deposit date: | 2021-05-13 | Release date: | 2021-09-15 | Last modified: | 2021-10-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity. J.Biol.Chem., 297, 2021
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7MTC
| Structure of freshly purified SARS-CoV-2 S2P spike at pH 7.4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Tsybovsky, Y, Olia, A.S, Kwong, P.D. | Deposit date: | 2021-05-13 | Release date: | 2021-09-15 | Last modified: | 2021-10-13 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity. J.Biol.Chem., 297, 2021
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7MTE
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8TE7
| Structure of TRNM-f.01 | Descriptor: | TRNM-f.01 Fab Heavy Chain, TRNM-f.01 Fab Light Chain | Authors: | Bender, M.F, Olia, A.S, Kwong, P.D. | Deposit date: | 2023-07-05 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | Broad and Potent HIV-1 Neutralization in Fusion Peptide-primed SHIV-boosted Macaques To Be Published
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5T53
| MOLECULAR BASIS FOR COHESIN ACETYLATION BY ESTABLISHMENT OF SISTER CHROMATID COHESION N-ACETYLTRANSFERASE ESCO1 | Descriptor: | ACETYL COENZYME *A, N-acetyltransferase ESCO1, ZINC ION | Authors: | Marmorstein, R, Rivera-Colon, Y, Liszczak, G.P, Olia, A.S, Maguire, A. | Deposit date: | 2016-08-30 | Release date: | 2016-11-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.699 Å) | Cite: | Molecular Basis for Cohesin Acetylation by Establishment of Sister Chromatid Cohesion N-Acetyltransferase ESCO1. J. Biol. Chem., 291, 2016
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6VZI
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7Z7C
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8AED
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5BVZ
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9BEW
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9BER
| Cryo-EM structure of the HIV-1 JR-FL IDL Env trimer in complex with PGT122 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Gorman, J, Kwong, P.D. | Deposit date: | 2024-04-16 | Release date: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation. Cell Rep, 43, 2024
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9BF6
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8DW2
| Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR22, and two antibody Fabs, S309 and CR3022 | Descriptor: | Antibody CR3022 heavy chain, Antibody CR3022 light chain, Antibody S309 heavy chain, ... | Authors: | Kwon, Y.D, Gorman, J, Kwong, P.D. | Deposit date: | 2022-07-30 | Release date: | 2022-12-07 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (4.11 Å) | Cite: | A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins. Nat.Chem.Biol., 19, 2023
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8DW3
| Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR16m, and two antibody Fabs, S309 and CR3022 | Descriptor: | Anti-SARS-CoV-2 DARPin SR16m, Antibody S309 light chain, Spike protein S1, ... | Authors: | Kwon, Y.D, Gorman, J, Kwong, P.D. | Deposit date: | 2022-07-30 | Release date: | 2022-12-07 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (4.26 Å) | Cite: | A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins. Nat.Chem.Biol., 19, 2023
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6XM4
| Structure of SARS-CoV-2 spike at pH 5.5, single RBD up, conformation 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Zhou, T, Tsybovsky, Y, Olia, A, Kwong, P.D. | Deposit date: | 2020-06-29 | Release date: | 2020-08-12 | Last modified: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains. Cell Host Microbe, 28, 2020
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