Author results

1XMA
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STRUCTURE OF A TRANSCRIPTIONAL REGULATOR FROM CLOSTRIDIUM THERMOCELLUM CTH-833
分子名称:Predicted transcriptional regulator, MERCURY (II) ION, UNKNOWN ATOM OR ION
著者Yang, H., Chen, L., Lee, D., Habel, J., Nguyen, J., Chang, S.-H., Kataeva, I., Xu, H., Chang, J., Zhao, M., Horanyi, P., Florence, Q., Zhou, W., Tempel, W., Lin, D., Praissman, J., Zhang, H., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Ljungdahl, L., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-10-01
公開日2004-12-14
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structure of a transcriptional regulator from Clostridium thermocellum Cth-833
To be published
1XRG
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CONSERVED HYPOTHETICAL PROTEIN FROM CLOSTRIDIUM THERMOCELLUM CTH-2968
分子名称:Putative translation initiation inhibitor, yjgF family, UNKNOWN ATOM OR ION
著者Zhao, M., Chang, J., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Zhou, W., Tempel, W., Lin, D., Zhang, H., Arendall III, W.B., Ljundahl, L., Liu, Z.-J., Rose, J., Richardson, J.S., Richardson, D.C., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-10-14
公開日2004-12-14
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conserved hypothetical protein from Clostridium thermocellum Cth-2968
To be published
1YBX
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CONSERVED HYPOTHETICAL PROTEIN CTH-383 FROM CLOSTRIDIUM THERMOCELLUM
分子名称:Conserved hypothetical protein, UNKNOWN ATOM OR ION
著者Tempel, W., Chang, J., Zhao, M., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Zhou, W., Lin, D., Zhang, H., Ljundahl, L., Liu, Z.-J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-12-21
公開日2005-02-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conserved hypothetical protein Cth-383 from Clostridium thermocellum
To be published
1YBY
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CONSERVED HYPOTHETICAL PROTEIN CTH-95 FROM CLOSTRIDIUM THERMOCELLUM
分子名称:Translation elongation factor P, UNKNOWN ATOM OR ION
著者Zhao, M., Zhou, W., Chang, J., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Tempel, W., Lin, D., Zhang, H., Ljundahl, L., Liu, Z.-J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-12-21
公開日2005-02-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Conserved hypothetical protein Cth-95 from Clostridium thermocellum
To be published
4DLO
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CRYSTAL STRUCTURE OF THE GAIN AND HORMR DOMAINS OF BRAIN ANGIOGENESIS INHIBITOR 3 (BAI3)
分子名称:Brain-specific angiogenesis inhibitor 3, N-ACETYL-D-GLUCOSAMINE, BETA-L-FUCOSE, ...
著者Arac, D., Boucard, A.A., Bolliger, M.F., Nguyen, J., Soltis, M., Sudhof, T.C., Brunger, A.T.
登録日2012-02-06
公開日2012-02-22
最終更新日2014-07-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis.
Embo J., 31, 2012
4DLQ
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CRYSTAL STRUCTURE OF THE GAIN AND HORMR DOMAINS OF CIRL 1/LATROPHILIN 1 (CL1)
分子名称:Latrophilin-1, N-ACETYL-D-GLUCOSAMINE, SULFATE ION, ...
著者Arac, D., Boucard, A.A., Bolliger, M.F., Nguyen, J., Soltis, M., Sudhof, T.C., Brunger, A.T.
登録日2012-02-06
公開日2012-02-22
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis.
Embo J., 31, 2012
4PHU
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CRYSTAL STRUCTURE OF HUMAN GPR40 BOUND TO ALLOSTERIC AGONIST TAK-875
分子名称:Free fatty acid receptor 1,Lysozyme, [(3S)-6-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy]biphenyl-3-yl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
著者Srivastava, A., Yano, J.K., Hirozane, Y., Kefala, G., Snell, G., Lane, W., Gruswitz, F., Ivetac, A., Aertgeerts, K., Nguyen, J., Jennings, A., Okada, K.
登録日2014-05-07
公開日2014-07-16
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.332 Å)
主引用文献High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
Nature, 513, 2014
1ZD0
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CRYSTAL STRUCTURE OF PFU-542154 CONSERVED HYPOTHETICAL PROTEIN
分子名称:hypothetical protein PF0523, MAGNESIUM ION, UNKNOWN ATOM OR ION, ...
著者Habel, J.E., Liu, Z.J., Horanyi, P.S., Florence, Q.J.T., Tempel, W., Zhou, W., Chen, L., Lee, D., Nguyen, J., Chang, S.H., Bereton, P., Izumi, M., Jenny Jr., F.E., Poole II, F.L., Shah, C., Sugar, F.J., Adams, M.W.W., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2005-04-13
公開日2005-05-17
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Pfu-542154 conserved hypothetical protein
To be Published
2A4K
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3-OXOACYL-[ACYL CARRIER PROTEIN] REDUCTASE FROM THERMUS THERMOPHILUS TT0137
分子名称:3-oxoacyl-[acyl carrier protein] reductase, UNKNOWN ATOM OR ION
著者Zhou, W., Ebihara, A., Tempel, W., Yokoyama, S., Chen, L., Kuramitsu, S., Nguyen, J., Chang, S.-H., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-06-29
公開日2006-01-10
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献3-Oxoacyl-[acyl carrier protein] reductase from Thermus thermophilus TT0137
To be Published
1XHO
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CHORISMATE MUTASE FROM CLOSTRIDIUM THERMOCELLUM CTH-682
分子名称:Chorismate mutase, UNKNOWN ATOM OR ION
著者Xu, H., Chen, L., Lee, D., Habel, J.E., Nguyen, J., Chang, S.-H., Kataeva, I., Chang, J., Zhao, M., Yang, H., Horanyi, P., Florence, Q., Tempel, W., Zhou, W., Lin, D., Zhang, H., Praissman, J., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Ljungdahl, L., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-09-20
公開日2004-11-23
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Away from the edge II: in-house Se-SAS phasing with chromium radiation.
Acta Crystallogr.,Sect.D, 61, 2005
3LIN
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CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH THE INHIBITOR, KNI-10562
分子名称:Protease, N-[(2S,3S)-4-{(4R)-4-[(2,2-dimethylpropyl)carbamoyl]-5,5-dimethyl-1,3-thiazolidin-3-yl}-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-N~2~-{(2S)-2-[(methoxycarbonyl)amino]-2-phenylacetyl}-3-methyl-L-valinamide
著者Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
登録日2010-01-25
公開日2010-07-14
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
3LIQ
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CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH THE INHIBITOR, KNI-10673
分子名称:Protease, (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-butanoyl]-5,5-dimethyl-N-(2-methylpropyl)-1,3-thiazolidine-4-carboxamide
著者Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
登録日2010-01-25
公開日2010-07-14
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
3LIT
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THE CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH THE INHIBITOR KNI-10681
分子名称:Protease, (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-butanoyl]-5,5-dimethyl-N-[(2R)-3-methylbutan-2-yl]-1,3-thiazolidine-4-carboxamide
著者Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
登録日2010-01-25
公開日2010-07-14
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
3LIV
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CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH THE INHIBITOR KNI-10683
分子名称:Protease, (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-butanoyl]-N-[(2R)-3,3-dimethylbutan-2-yl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide
著者Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
登録日2010-01-25
公開日2010-07-14
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
3LIX
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CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH THE INHIBITOR KNI-10729
分子名称:Protease, ZINC ION, N-{(1S,2S)-1-benzyl-3-[(4R)-5,5-dimethyl-4-{[(1R)-1,2,2-trimethylpropyl]carbamoyl}-1,3-thiazolidin-3-yl]-2-hydroxy-3-oxopropyl}-3-methyl-N~2~-{(2S)-2-[(morpholin-4-ylacetyl)amino]-2-phenylacetyl}-L-valinamide
著者Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
登録日2010-01-25
公開日2010-07-14
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
3LIY
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CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH STATINE-CONTAINING PEPTIDE INHIBITOR
分子名称:Protease, statine-containing inhibitor, DI(HYDROXYETHYL)ETHER
著者Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
登録日2010-01-25
公開日2010-07-14
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
4LH4
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DUAL INHIBITION OF HIV-1 REPLICATION BY INTEGRASE-LEDGF ALLOSTERIC INHIBITORS IS PREDOMINANT AT POST-INTEGRATION STAGE DURING VIRUS PRODUCTION RATHER THAN AT INTEGRATION
分子名称:Integrase, MAGNESIUM ION
著者Ruff, M., Levy, N., Eiler, S.
登録日2013-06-30
公開日2013-12-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage.
Retrovirology, 10, 2013
4LH5
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DUAL INHIBITION OF HIV-1 REPLICATION BY INTEGRASE-LEDGF ALLOSTERIC INHIBITORS IS PREDOMINANT AT POST-INTEGRATION STAGE DURING VIRUS PRODUCTION RATHER THAN AT INTEGRATION
分子名称:Integrase, (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, MAGNESIUM ION
著者Ruff, M., Levy, N., Eiler, S.
登録日2013-06-30
公開日2013-12-25
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage.
Retrovirology, 10, 2013
4YP0
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH 5-AMINOISOQUINOLINE (CHEM 79)
分子名称:Histidyl-tRNA synthetase, HISTIDINE, ISOQUINOLIN-5-AMINE, ...
著者Koh, C.-Y., Hol, W.G.J.
登録日2015-03-12
公開日2015-08-12
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YPF
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH QUINOLIN-3-AMINE (CHEM 84)
分子名称:Histidyl-tRNA synthetase, HISTIDINE, quinolin-3-amine, ...
著者Koh, C.-Y., Hol, W.G.J.
登録日2015-03-12
公開日2015-08-12
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRC
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH 2-AMINOQUINOLIN-8-OL (CHEM 89)
分子名称:Histidyl-tRNA synthetase, HISTIDINE, 2-aminoquinolin-8-ol, ...
著者Koh, C.-Y., Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRE
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH (2-BROMOPHENYL)METHANOL (CHEM 145)
分子名称:Histidyl-tRNA synthetase, HISTIDINE, (2-bromophenyl)methanol, ...
著者Koh, C.-Y., Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRF
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH 5-BROMOPYRIDIN-2(1H)-ONE (CHEM 148)
分子名称:Histidyl-tRNA synthetase, putative, HISTIDINE, ...
著者Koh, C.-Y., Hol, W.G.J.
登録日2015-03-15
公開日2015-08-19
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr.,Sect.D, 71, 2015
4YRG
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH (6-BROMOPYRIDIN-2-YL)METHANOL (CHEM 149)
分子名称:Histidyl-tRNA synthetase, HISTIDINE, (6-bromopyridin-2-yl)methanol, ...
著者Koh, C.-Y., Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRI
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH 1-(3-BROMOPHENYL)METHANAMINE (CHEM 166)
分子名称:Histidyl-tRNA synthetase, putative, HISTIDINE, ...
著者Koh, C.-Y., Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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