Author results

1XMA
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STRUCTURE OF A TRANSCRIPTIONAL REGULATOR FROM CLOSTRIDIUM THERMOCELLUM CTH-833
Descriptor:Predicted transcriptional regulator, MERCURY (II) ION, UNKNOWN ATOM OR ION
Authors:Yang, H., Chen, L., Lee, D., Habel, J., Nguyen, J., Chang, S.-H., Kataeva, I., Xu, H., Chang, J., Zhao, M., Horanyi, P., Florence, Q., Zhou, W., Tempel, W., Lin, D., Praissman, J., Zhang, H., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Ljungdahl, L., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-10-01
Release date:2004-12-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structure of a transcriptional regulator from Clostridium thermocellum Cth-833
To be published
1XRG
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CONSERVED HYPOTHETICAL PROTEIN FROM CLOSTRIDIUM THERMOCELLUM CTH-2968
Descriptor:Putative translation initiation inhibitor, yjgF family, UNKNOWN ATOM OR ION
Authors:Zhao, M., Chang, J., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Zhou, W., Tempel, W., Lin, D., Zhang, H., Arendall III, W.B., Ljundahl, L., Liu, Z.-J., Rose, J., Richardson, J.S., Richardson, D.C., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-10-14
Release date:2004-12-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conserved hypothetical protein from Clostridium thermocellum Cth-2968
To be published
1YBX
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CONSERVED HYPOTHETICAL PROTEIN CTH-383 FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:Conserved hypothetical protein, UNKNOWN ATOM OR ION
Authors:Tempel, W., Chang, J., Zhao, M., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Zhou, W., Lin, D., Zhang, H., Ljundahl, L., Liu, Z.-J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-21
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conserved hypothetical protein Cth-383 from Clostridium thermocellum
To be published
1YBY
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CONSERVED HYPOTHETICAL PROTEIN CTH-95 FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:Translation elongation factor P, UNKNOWN ATOM OR ION
Authors:Zhao, M., Zhou, W., Chang, J., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Tempel, W., Lin, D., Zhang, H., Ljundahl, L., Liu, Z.-J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-21
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Conserved hypothetical protein Cth-95 from Clostridium thermocellum
To be published
4DLO
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CRYSTAL STRUCTURE OF THE GAIN AND HORMR DOMAINS OF BRAIN ANGIOGENESIS INHIBITOR 3 (BAI3)
Descriptor:Brain-specific angiogenesis inhibitor 3, N-ACETYL-D-GLUCOSAMINE, BETA-L-FUCOSE, ...
Authors:Arac, D., Boucard, A.A., Bolliger, M.F., Nguyen, J., Soltis, M., Sudhof, T.C., Brunger, A.T.
Deposit date:2012-02-06
Release date:2012-02-22
Last modified:2014-07-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis.
Embo J., 31, 2012
4DLQ
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CRYSTAL STRUCTURE OF THE GAIN AND HORMR DOMAINS OF CIRL 1/LATROPHILIN 1 (CL1)
Descriptor:Latrophilin-1, N-ACETYL-D-GLUCOSAMINE, SULFATE ION, ...
Authors:Arac, D., Boucard, A.A., Bolliger, M.F., Nguyen, J., Soltis, M., Sudhof, T.C., Brunger, A.T.
Deposit date:2012-02-06
Release date:2012-02-22
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis.
Embo J., 31, 2012
4PHU
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CRYSTAL STRUCTURE OF HUMAN GPR40 BOUND TO ALLOSTERIC AGONIST TAK-875
Descriptor:Free fatty acid receptor 1,Lysozyme, [(3S)-6-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy]biphenyl-3-yl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
Authors:Srivastava, A., Yano, J.K., Hirozane, Y., Kefala, G., Snell, G., Lane, W., Gruswitz, F., Ivetac, A., Aertgeerts, K., Nguyen, J., Jennings, A., Okada, K.
Deposit date:2014-05-07
Release date:2014-07-16
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.332 Å)
Cite:High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
Nature, 513, 2014
1ZD0
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CRYSTAL STRUCTURE OF PFU-542154 CONSERVED HYPOTHETICAL PROTEIN
Descriptor:hypothetical protein PF0523, MAGNESIUM ION, UNKNOWN ATOM OR ION, ...
Authors:Habel, J.E., Liu, Z.J., Horanyi, P.S., Florence, Q.J.T., Tempel, W., Zhou, W., Chen, L., Lee, D., Nguyen, J., Chang, S.H., Bereton, P., Izumi, M., Jenny Jr., F.E., Poole II, F.L., Shah, C., Sugar, F.J., Adams, M.W.W., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-04-13
Release date:2005-05-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Pfu-542154 conserved hypothetical protein
To be Published
2A4K
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3-OXOACYL-[ACYL CARRIER PROTEIN] REDUCTASE FROM THERMUS THERMOPHILUS TT0137
Descriptor:3-oxoacyl-[acyl carrier protein] reductase, UNKNOWN ATOM OR ION
Authors:Zhou, W., Ebihara, A., Tempel, W., Yokoyama, S., Chen, L., Kuramitsu, S., Nguyen, J., Chang, S.-H., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-06-29
Release date:2006-01-10
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:3-Oxoacyl-[acyl carrier protein] reductase from Thermus thermophilus TT0137
To be Published
1XHO
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CHORISMATE MUTASE FROM CLOSTRIDIUM THERMOCELLUM CTH-682
Descriptor:Chorismate mutase, UNKNOWN ATOM OR ION
Authors:Xu, H., Chen, L., Lee, D., Habel, J.E., Nguyen, J., Chang, S.-H., Kataeva, I., Chang, J., Zhao, M., Yang, H., Horanyi, P., Florence, Q., Tempel, W., Zhou, W., Lin, D., Zhang, H., Praissman, J., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Ljungdahl, L., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-09-20
Release date:2004-11-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Away from the edge II: in-house Se-SAS phasing with chromium radiation.
Acta Crystallogr.,Sect.D, 61, 2005
3LIN
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CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH THE INHIBITOR, KNI-10562
Descriptor:Protease, N-[(2S,3S)-4-{(4R)-4-[(2,2-dimethylpropyl)carbamoyl]-5,5-dimethyl-1,3-thiazolidin-3-yl}-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-N~2~-{(2S)-2-[(methoxycarbonyl)amino]-2-phenylacetyl}-3-methyl-L-valinamide
Authors:Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
Deposit date:2010-01-25
Release date:2010-07-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
3LIQ
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CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH THE INHIBITOR, KNI-10673
Descriptor:Protease, (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-butanoyl]-5,5-dimethyl-N-(2-methylpropyl)-1,3-thiazolidine-4-carboxamide
Authors:Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
Deposit date:2010-01-25
Release date:2010-07-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
3LIT
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THE CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH THE INHIBITOR KNI-10681
Descriptor:Protease, (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-butanoyl]-5,5-dimethyl-N-[(2R)-3-methylbutan-2-yl]-1,3-thiazolidine-4-carboxamide
Authors:Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
Deposit date:2010-01-25
Release date:2010-07-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
3LIV
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CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH THE INHIBITOR KNI-10683
Descriptor:Protease, (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-butanoyl]-N-[(2R)-3,3-dimethylbutan-2-yl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide
Authors:Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
Deposit date:2010-01-25
Release date:2010-07-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
3LIX
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CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH THE INHIBITOR KNI-10729
Descriptor:Protease, ZINC ION, N-{(1S,2S)-1-benzyl-3-[(4R)-5,5-dimethyl-4-{[(1R)-1,2,2-trimethylpropyl]carbamoyl}-1,3-thiazolidin-3-yl]-2-hydroxy-3-oxopropyl}-3-methyl-N~2~-{(2S)-2-[(morpholin-4-ylacetyl)amino]-2-phenylacetyl}-L-valinamide
Authors:Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
Deposit date:2010-01-25
Release date:2010-07-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
3LIY
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CRYSTAL STRUCTURE OF HTLV PROTEASE COMPLEXED WITH STATINE-CONTAINING PEPTIDE INHIBITOR
Descriptor:Protease, statine-containing inhibitor, DI(HYDROXYETHYL)ETHER
Authors:Satoh, T., Li, M., Nguyen, J., Kiso, Y., Wlodawer, A., Gustchina, A.
Deposit date:2010-01-25
Release date:2010-07-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease.
J.Mol.Biol., 401, 2010
4LH4
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DUAL INHIBITION OF HIV-1 REPLICATION BY INTEGRASE-LEDGF ALLOSTERIC INHIBITORS IS PREDOMINANT AT POST-INTEGRATION STAGE DURING VIRUS PRODUCTION RATHER THAN AT INTEGRATION
Descriptor:Integrase, MAGNESIUM ION
Authors:Ruff, M., Levy, N., Eiler, S.
Deposit date:2013-06-30
Release date:2013-12-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage.
Retrovirology, 10, 2013
4LH5
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DUAL INHIBITION OF HIV-1 REPLICATION BY INTEGRASE-LEDGF ALLOSTERIC INHIBITORS IS PREDOMINANT AT POST-INTEGRATION STAGE DURING VIRUS PRODUCTION RATHER THAN AT INTEGRATION
Descriptor:Integrase, (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, MAGNESIUM ION
Authors:Ruff, M., Levy, N., Eiler, S.
Deposit date:2013-06-30
Release date:2013-12-25
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage.
Retrovirology, 10, 2013
4YP0
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH 5-AMINOISOQUINOLINE (CHEM 79)
Descriptor:Histidyl-tRNA synthetase, HISTIDINE, ISOQUINOLIN-5-AMINE, ...
Authors:Koh, C.-Y., Hol, W.G.J.
Deposit date:2015-03-12
Release date:2015-08-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YPF
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH QUINOLIN-3-AMINE (CHEM 84)
Descriptor:Histidyl-tRNA synthetase, HISTIDINE, quinolin-3-amine, ...
Authors:Koh, C.-Y., Hol, W.G.J.
Deposit date:2015-03-12
Release date:2015-08-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRC
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH 2-AMINOQUINOLIN-8-OL (CHEM 89)
Descriptor:Histidyl-tRNA synthetase, HISTIDINE, 2-aminoquinolin-8-ol, ...
Authors:Koh, C.-Y., Hol, W.G.J.
Deposit date:2015-03-15
Release date:2015-08-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRE
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH (2-BROMOPHENYL)METHANOL (CHEM 145)
Descriptor:Histidyl-tRNA synthetase, HISTIDINE, (2-bromophenyl)methanol, ...
Authors:Koh, C.-Y., Hol, W.G.J.
Deposit date:2015-03-15
Release date:2015-08-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRF
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH 5-BROMOPYRIDIN-2(1H)-ONE (CHEM 148)
Descriptor:Histidyl-tRNA synthetase, putative, HISTIDINE, ...
Authors:Koh, C.-Y., Hol, W.G.J.
Deposit date:2015-03-15
Release date:2015-08-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr.,Sect.D, 71, 2015
4YRG
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH (6-BROMOPYRIDIN-2-YL)METHANOL (CHEM 149)
Descriptor:Histidyl-tRNA synthetase, HISTIDINE, (6-bromopyridin-2-yl)methanol, ...
Authors:Koh, C.-Y., Hol, W.G.J.
Deposit date:2015-03-15
Release date:2015-08-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRI
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CRYSTAL STRUCTURE OF T. CRUZI HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH 1-(3-BROMOPHENYL)METHANAMINE (CHEM 166)
Descriptor:Histidyl-tRNA synthetase, putative, HISTIDINE, ...
Authors:Koh, C.-Y., Hol, W.G.J.
Deposit date:2015-03-15
Release date:2015-08-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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