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3MHD
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BU of 3mhd by Molmil
Crystal structure of DCR3
Descriptor: Tumor necrosis factor receptor superfamily member 6B
Authors:Zhan, C, Patskovsky, Y, Yan, Q, Li, Z, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
Deposit date:2010-04-07
Release date:2011-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
3MI8
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BU of 3mi8 by Molmil
The structure of TL1A-DCR3 COMPLEX
Descriptor: TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15, SECRETED FORM, Tumor necrosis factor receptor superfamily member 6B
Authors:Zhan, C, Patskovsky, Y, Yan, Q, Li, Z, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
Deposit date:2010-04-09
Release date:2011-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.951 Å)
Cite:Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
3K51
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BU of 3k51 by Molmil
Crystal Structure of DcR3-TL1A complex
Descriptor: Decoy receptor 3, Tumor necrosis factor ligand superfamily member 15, secreted form
Authors:Zhan, C, Patskovsky, Y, Yan, Q, Li, Z, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
Deposit date:2009-10-06
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
1NCN
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BU of 1ncn by Molmil
the receptor-binding domain of human B7-2
Descriptor: T lymphocyte activation antigen CD86
Authors:Zhang, X, Schwartz, J.D, Almo, S.C, Nathenson, S.G.
Deposit date:2002-12-05
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of the Receptor-Binding Domain of Human B7-2: Insights into Organization and Signaling
Proc.Natl.Acad.Sci.USA, 100, 2003
1DQT
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BU of 1dqt by Molmil
THE CRYSTAL STRUCTURE OF MURINE CTLA4 (CD152)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CYTOTOXIC T LYMPHOCYTE ASSOCIATED ANTIGEN 4
Authors:Ostrov, D.A, Shi, W, Schwartz, J.C, Almo, S.C, Nathenson, S.G.
Deposit date:2000-01-05
Release date:2000-10-27
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of murine CTLA-4 and its role in modulating T cell responsiveness.
Science, 290, 2000
3SBW
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BU of 3sbw by Molmil
Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1
Descriptor: Programmed cell death 1 ligand 1, Programmed cell death protein 1
Authors:Lazar-Molnar, E, Ramagopal, U.A, Cao, E, Nathenson, S.G, Almo, S.C.
Deposit date:2011-06-06
Release date:2011-07-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1
To be published
2IF7
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BU of 2if7 by Molmil
Crystal Structure of NTB-A
Descriptor: CALCIUM ION, CHLORIDE ION, SLAM family member 6
Authors:Cao, E, Ramagopal, U.A, Fedorov, A.A, Fedorov, E.V, Nathenson, S.G, Almo, S.C.
Deposit date:2006-09-20
Release date:2006-10-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:NTB-A Receptor Crystal Structure: Insights into Homophilic Interactions in the Signaling Lymphocytic Activation Molecule Receptor Family.
Immunity, 25, 2006
3B9I
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BU of 3b9i by Molmil
Crystal Structure of mouse GITRL at 2.5 A.
Descriptor: GITR ligand
Authors:Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
Deposit date:2007-11-05
Release date:2008-01-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BP6
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BU of 3bp6 by Molmil
Crystal structure of the mouse PD-1 Mutant and PD-L2 complex
Descriptor: GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1
Authors:Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C.
Deposit date:2007-12-18
Release date:2009-02-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the mouse PD-1 A99L and PD-L2 complex
To be published
3BP5
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BU of 3bp5 by Molmil
Crystal structure of the mouse PD-1 and PD-L2 complex
Descriptor: GLYCEROL, Programmed cell death 1 ligand 2, Programmed cell death protein 1
Authors:Yan, Q, Lazar-Molnar, E, Cao, E, Ramagopal, U.A, Toro, R, Nathenson, S.G, Almo, S.C.
Deposit date:2007-12-18
Release date:2008-07-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1NPU
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BU of 1npu by Molmil
CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MURINE PD-1
Descriptor: Programmed cell death protein 1
Authors:Zhang, X, Schwartz, J.-C.D, Guo, X, Cao, E, Chen, L, Zhang, Z.-Y, Nathenson, S.G, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2003-01-20
Release date:2004-03-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analysis of the costimulatory receptor programmed death-1.
Immunity, 20, 2004
2MHA
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BU of 2mha by Molmil
CRYSTAL STRUCTURE OF THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I H-2KB MOLECULE CONTAINING A SINGLE VIRAL PEPTIDE: IMPLICATIONS FOR PEPTIDE BINDING AND T-CELL RECEPTOR RECOGNITION
Descriptor: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (H-2KB) (ALPHA CHAIN), VIRAL OCTAPEPTIDE ARG-GLY-TYR-VAL-TYR-GLN-GLY-LEU
Authors:Zhang, W, Young, A.C.M, Imarai, M, Nathenson, S.G, Sacchettini, J.C.
Deposit date:1993-07-21
Release date:1993-10-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition.
Proc.Natl.Acad.Sci.USA, 89, 1992
2Q1M
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BU of 2q1m by Molmil
Crystal Structure of human GITRL
Descriptor: Tumor necrosis factor ligand superfamily member 18
Authors:Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
Deposit date:2007-05-24
Release date:2007-11-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.
Proc.Natl.Acad.Sci.USA, 104, 2007
2OYP
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BU of 2oyp by Molmil
T Cell Immunoglobulin Mucin-3 Crystal Structure Revealed a Galectin-9-independent Binding Surface
Descriptor: Hepatitis A virus cellular receptor 2, SULFATE ION
Authors:Cao, E, Ramagopal, U.A, Fedorov, A.A, Fedorov, E.V, Nathenson, S.G, Almo, S.C.
Deposit date:2007-02-22
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface
Immunity, 26, 2007
2PKD
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BU of 2pkd by Molmil
Crystal structure of CD84: Insite into SLAM family function
Descriptor: CHLORIDE ION, SLAM family member 5
Authors:Yan, Q, Malashkevich, V.N, Fedorov, A, Cao, E, Lary, J.W, Cole, J.L, Nathenson, S.G, Almo, S.C.
Deposit date:2007-04-17
Release date:2007-06-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:Structure of CD84 provides insight into SLAM family function.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1INQ
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BU of 1inq by Molmil
Structure of Minor Histocompatibility Antigen peptide, H13a, complexed to H2-Db
Descriptor: BETA-2 MICROGLOBULIN, DIMETHYL SULFOXIDE, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Ostrov, D.A, Roden, M.M, Shi, W, Palmieri, E, Christianson, G.J, Mendoza, L, Villaflor, G, Tilley, D, Shastri, N, Grey, H, Almo, S.C, Roopenian, D, Nathenson, S.G.
Deposit date:2001-05-14
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination.
J.Immunol., 168, 2002
1I85
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BU of 1i85 by Molmil
CRYSTAL STRUCTURE OF THE CTLA-4/B7-2 COMPLEX
Descriptor: CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, T LYMPHOCYTE ACTIVATION ANTIGEN CD86
Authors:Schwartz, J.-C.D, Zhang, X, Fedorov, A.A, Nathenson, S.G, Almo, S.C.
Deposit date:2001-03-12
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for co-stimulation by the human CTLA-4/B7-2 complex.
Nature, 410, 2001
1JUF
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BU of 1juf by Molmil
Structure of Minor Histocompatibility Antigen peptide, H13b, complexed to H2-Db
Descriptor: Beta-2-microglobulin, H13b peptide, H2-Db major histocompatibility antigen
Authors:Ostrov, D.A, Roden, M.M, Shi, W, Palmieri, E, Christianson, G.J, Mendoza, L, Villaflor, G, Tilley, D, Shastri, N, Grey, H, Almo, S.C, Roopenian, D.C, Nathenson, S.G.
Deposit date:2001-08-24
Release date:2002-03-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:How H13 histocompatibility peptides differing by a single methyl group and lacking conventional MHC binding anchor motifs determine self-nonself discrimination.
J.Immunol., 168, 2002
1LD9
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BU of 1ld9 by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF AN H-2LD PEPTIDE COMPLEX EXPLAINS THE UNIQUE INTERACTION OF LD WITH BETA2M AND PEPTIDE
Descriptor: BETA-2 MICROGLOBULIN, MHC CLASS I H-2LD HEAVY CHAIN, NANO-PEPTIDE
Authors:Balendiran, G.K, Solheim, J.C, Young, A.C.M, Hansen, T.H, Nathenson, S.G, Sacchettini, J.C.
Deposit date:1997-04-24
Release date:1998-05-06
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The three-dimensional structure of an H-2Ld-peptide complex explains the unique interaction of Ld with beta-2 microglobulin and peptide.
Proc.Natl.Acad.Sci.USA, 94, 1997
3BOV
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BU of 3bov by Molmil
Crystal structure of the receptor binding domain of mouse PD-L2
Descriptor: FORMIC ACID, Programmed cell death 1 ligand 2, SODIUM ION
Authors:Lazar-Molnar, E, Ramagopal, U, Cao, E, Toro, R, Nathenson, S.G, Almo, S.C.
Deposit date:2007-12-17
Release date:2008-07-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.
Proc.Natl.Acad.Sci.USA, 105, 2008
3FON
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BU of 3fon by Molmil
Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide VNDIFEAI
Descriptor: Beta-2-microglobulin, MHC, Peptide
Authors:Malashkevich, V.N, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Brims, D.R, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P.
Deposit date:2008-12-30
Release date:2010-01-12
Last modified:2020-02-05
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.
Int.Immunol., 22, 2010
3FOL
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BU of 3fol by Molmil
Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide VNDIFERI
Descriptor: 8 residue synthetic peptide, Beta-2-microglobulin, MHC
Authors:Brims, D.R, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Malashkevich, V.N, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P.
Deposit date:2008-12-30
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect
Int.Immunol., 22, 2010
3FOM
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BU of 3fom by Molmil
Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide IQQSIERL
Descriptor: 8 residue synthetic peptide, Beta-2-microglobulin, CHLORIDE ION, ...
Authors:Brims, D.R, Qian, J, Jarchum, I, Yamada, T, Mikesh, L, Palmieri, E, Lund, T, Hattori, M, Shabanowitz, J, Hunt, D.F, Ramagopal, U.A, Malashkevich, V.N, Almo, S.C, Nathenson, S.G, DiLorenzo, T.P.
Deposit date:2008-12-30
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.
Int.Immunol., 22, 2010
3FC0
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BU of 3fc0 by Molmil
1.8 A crystal structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells
Descriptor: ACETATE ION, GITR ligand
Authors:Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
Deposit date:2008-11-20
Release date:2008-12-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:1.8 A structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells.
Acta Crystallogr.,Sect.D, 65, 2009
4I0K
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BU of 4i0k by Molmil
Crystal structure of murine B7-H3 extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD276 antigen, SULFATE ION, ...
Authors:Vigdorovich, V, Ramagopal, U, Bonanno, J.B, Toro, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-11-16
Release date:2012-12-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structure and T cell inhibition properties of B7 family member, B7-H3.
Structure, 21, 2013

 

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