3FOM
Crystal structure of the Class I MHC Molecule H-2Kwm7 with a Single Self Peptide IQQSIERL
Summary for 3FOM
Entry DOI | 10.2210/pdb3fom/pdb |
Related | 3FOL 3FON |
Descriptor | MHC, Beta-2-microglobulin, 8 residue synthetic peptide, ... (5 entities in total) |
Functional Keywords | class i mhc, peptide complex, diabetes-protective effect, immune response, immunoglobulin domain, mhc i, secreted, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Secreted: P01887 |
Total number of polymer chains | 3 |
Total formula weight | 44345.23 |
Authors | Brims, D.R.,Qian, J.,Jarchum, I.,Yamada, T.,Mikesh, L.,Palmieri, E.,Lund, T.,Hattori, M.,Shabanowitz, J.,Hunt, D.F.,Ramagopal, U.A.,Malashkevich, V.N.,Almo, S.C.,Nathenson, S.G.,DiLorenzo, T.P. (deposition date: 2008-12-30, release date: 2010-01-12, Last modification date: 2017-11-01) |
Primary citation | Brims, D.R.,Qian, J.,Jarchum, I.,Mikesh, L.,Palmieri, E.,Ramagopal, U.A.,Malashkevich, V.N.,Chaparro, R.J.,Lund, T.,Hattori, M.,Shabanowitz, J.,Hunt, D.F.,Nathenson, S.G.,Almo, S.C.,Dilorenzo, T.P. Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect. Int.Immunol., 22:191-203, 2010 Cited by PubMed: 20093428DOI: 10.1093/intimm/dxp127 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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