Author results

1J90
  • Download 1j90
  • View 1j90
Molmil generated image of 1j90
CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE
Descriptor:Deoxyribonucleoside kinase, SULFATE ION, 2'-DEOXYCYTIDINE
Authors:Johansson, K., Ramaswamy, S., Ljungkrantz, C., Knecht, W., Piskur, J., Munch-Petersen, B., Eriksson, S., Eklund, H.
Deposit date:2001-05-23
Release date:2001-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural basis for substrate specificities of cellular deoxyribonucleoside kinases.
Nat.Struct.Biol., 8, 2001
1OE0
  • Download 1oe0
  • View 1oe0
Molmil generated image of 1oe0
CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE IN COMPLEX WITH DTTP
Descriptor:DEOXYRIBONUCLEOSIDE KINASE, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Mikkelsen, N.E., Johansson, K., Karlsson, A., Knecht, W., Andersen, G., Piskur, J., Munch-Petersen, B., Eklund, H.
Deposit date:2003-03-17
Release date:2003-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway:Studies of the Drosophila Deoxyribonucleoside Kinase
Biochemistry, 42, 2003
1OT3
  • Download 1ot3
  • View 1ot3
Molmil generated image of 1ot3
CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOTIDE KINASE COMPLEXED WITH THE SUBSTRATE DEOXYTHYMIDINE
Descriptor:Deoxyribonucleoside Kinase, SULFATE ION, THYMIDINE
Authors:Mikkelsen, N.E., Johansson, K., Karlsson, A., Knecht, W., Andersen, G., Piskur, J., Munch-Petersen, B., Eklund, H.
Deposit date:2003-03-21
Release date:2003-05-27
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway: Studies of the Drosophila Deoxyribonucleoside Kinase.
Biochemistry, 42, 2003
1XBT
  • Download 1xbt
  • View 1xbt
Molmil generated image of 1xbt
CRYSTAL STRUCTURE OF HUMAN THYMIDINE KINASE 1
Descriptor:Thymidine kinase, cytosolic, ZINC ION, ...
Authors:Welin, M., Kosinska, U., Mikkelsen, N.E., Carnrot, C., Zhu, C., Wang, L., Eriksson, S., Munch-Petersen, B., Eklund, H.
Deposit date:2004-08-31
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of thymidine kinase 1 of human and mycoplasmic origin
Proc.Natl.Acad.Sci.Usa, 101, 2004
1ZM7
  • Download 1zm7
  • View 1zm7
Molmil generated image of 1zm7
CRYSTAL STRUCTURE OF D. MELANOGASTER DEOXYRIBONUCLEOSIDE KINASE MUTANT N64D IN COMPLEX WITH DTTP
Descriptor:Deoxynucleoside kinase, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Welin, M., Skovgaard, T., Knecht, W., Berenstein, D., Munch-Petersen, B., Piskur, J., Eklund, H.
Deposit date:2005-05-10
Release date:2005-05-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D.
Febs J., 272, 2005
1ZMX
  • Download 1zmx
  • View 1zmx
Molmil generated image of 1zmx
CRYSTAL STRUCTURE OF D. MELANOGASTER DEOXYRIBONUCLEOSIDE KINASE N64D MUTANT IN COMPLEX WITH THYMIDINE
Descriptor:Deoxynucleoside kinase, SULFATE ION, THYMIDINE
Authors:Welin, M., Skovgaard, T., Knecht, W., Berenstein, D., Munch-Petersen, B., Piskur, J., Eklund, H.
Deposit date:2005-05-11
Release date:2005-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D.
Febs J., 272, 2005
2JCS
  • Download 2jcs
  • View 2jcs
Molmil generated image of 2jcs
ACTIVE SITE MUTANT OF DNK FROM D. MELANOGASTER WITH DTTP BOUND
Descriptor:DEOXYNUCLEOSIDE KINASE, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Egeblad-Welin, L., Sonntag, Y., Eklund, H., Munch-Petersen, B.
Deposit date:2007-01-03
Release date:2007-02-27
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Functional Studies of Active-Site Mutants from Drosophila Melanogaster Deoxyribonucleoside Kinase. Investigations of the Putative Catalytic Glutamate- Arginine Pair and of Residues Responsible for Substrate Specificity.
FEBS J., 274, 2007
2JJ8
  • Download 2jj8
  • View 2jj8
Molmil generated image of 2jj8
STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE
Descriptor:DEOXYNUCLEOSIDE KINASE, SULFATE ION, 3'-azido-3'-deoxythymidine
Authors:Mikkelsen, N.E., Munch-Petersen, B., Eklund, H.
Deposit date:2008-03-19
Release date:2008-04-29
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275, 2008
2OCP
  • Download 2ocp
  • View 2ocp
Molmil generated image of 2ocp
CRYSTAL STRUCTURE OF HUMAN DEOXYGUANOSINE KINASE
Descriptor:Deoxyguanosine kinase, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
Authors:Johansson, K., Ramaswamy, S., Ljungkrantz, C., Knecht, W., Piskur, J., Munch-Petersen, B., Eriksson, S., Eklund, H.
Deposit date:2006-12-21
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Substrate Specificities of Cellular Deoxyribonucleoside Kinases.
Nat.Struct.Biol., 8, 2001
2UZ3
  • Download 2uz3
  • View 2uz3
Molmil generated image of 2uz3
CRYSTAL STRUCTURE OF THYMIDINE KINASE WITH DTTP FROM U. UREALYTICUM
Descriptor:THYMIDINE KINASE, ZINC ION, THYMIDINE-5'-TRIPHOSPHATE, ...
Authors:Welin, M., Kosinska, U., Mikkelsen, N.E., Carnrot, C., Zhu, C., Wang, L., Eriksson, S., Munch-Petersen, B., Eklund, H.
Deposit date:2007-04-24
Release date:2007-05-29
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of Thymidine Kinase 1 of Human and Mycoplasmic Origin
Proc.Natl.Acad.Sci.USA, 101, 2004
2VP0
  • Download 2vp0
  • View 2vp0
Molmil generated image of 2vp0
STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE
Descriptor:DEOXYNUCLEOSIDE KINASE, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE
Authors:Mikkelsen, N.E., Munch-Petersen, B., Eklund, H.
Deposit date:2008-02-26
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275, 2008
2VP2
  • Download 2vp2
  • View 2vp2
Molmil generated image of 2vp2
STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE
Descriptor:DEOXYNUCLEOSIDE KINASE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
Authors:Mikkelsen, N.E., Munch-Petersen, B., Eklund, H.
Deposit date:2008-02-26
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275, 2008
2VP4
  • Download 2vp4
  • View 2vp4
Molmil generated image of 2vp4
STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE
Descriptor:DEOXYNUCLEOSIDE KINASE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE
Authors:Mikkelsen, N.E., Munch-Petersen, B., Eklund, H.
Deposit date:2008-02-26
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275, 2008
2VP5
  • Download 2vp5
  • View 2vp5
Molmil generated image of 2vp5
STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE
Descriptor:DEOXYNUCLEOSIDE KINASE, SULFATE ION, 2'-DEOXYCYTIDINE
Authors:Mikkelsen, N.E., Munch-Petersen, B., Eklund, H.
Deposit date:2008-02-26
Release date:2008-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275, 2008
2VP6
  • Download 2vp6
  • View 2vp6
Molmil generated image of 2vp6
STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE
Descriptor:DEOXYNUCLEOSIDE KINASE, SULFATE ION, 5-FLUORO-URIDINE-5'-MONOPHOSPHATE
Authors:Mikkelsen, N.E., Munch-Petersen, B., Eklund, H.
Deposit date:2008-02-26
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275, 2008
2VP9
  • Download 2vp9
  • View 2vp9
Molmil generated image of 2vp9
STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE
Descriptor:DEOXYNUCLEOSIDE KINASE, SULFATE ION, 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE
Authors:Mikkelsen, N.E., Munch-Petersen, B., Eklund, H.
Deposit date:2008-02-27
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275, 2008
2VQS
  • Download 2vqs
  • View 2vqs
Molmil generated image of 2vqs
STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE
Descriptor:DEOXYNUCLEOSIDE KINASE, SULFATE ION, 5-BROMOVINYLDEOXYURIDINE
Authors:Mikkelsen, N.E., Munch-Petersen, B., Eklund, H.
Deposit date:2008-03-18
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275, 2008
2WVJ
  • Download 2wvj
  • View 2wvj
Molmil generated image of 2wvj
MUTATION OF THR163 TO SER IN HUMAN THYMIDINE KINASE SHIFTS THE SPECIFICITY FROM THYMIDINE TOWARDS THE NUCLEOSIDE ANALOGUE AZIDOTHYMIDINE
Descriptor:THYMIDINE KINASE, CYTOSOLIC, THYMIDINE-5'-TRIPHOSPHATE, ...
Authors:Skovgaard, T., Uhlin, U., Munch-Petersen, B.
Deposit date:2009-10-17
Release date:2009-10-27
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Comparative Active-Site Mutation Study of Human and Caenorhabditis Elegans Thymidine Kinase 1.
FEBS J., 279, 2012