2VP0

Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase

Summary for 2VP0

Related1ZM7 2JCS 1OT3 1OE0 1ZMX 1J90
DescriptorDEOXYNUCLEOSIDE KINASE, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywordsatp-binding, dna synthesis, phosphoprotein, feedback inhibition, deoxyribonucleoside kinase, salvage pathway, nucleotide-binding, dttp, kinase, complex, drosophila, transferase
Biological sourceDROSOPHILA MELANOGASTER (FRUIT FLY)
Total number of polymer chains2
Total molecular weight59267.45
Authors
Mikkelsen, N.E.,Munch-Petersen, B.,Eklund, H. (deposition date: 2008-02-26, release date: 2008-04-29, Last modification date: 2011-07-13)
Primary citation
Mikkelsen, N.E.,Munch-Petersen, B.,Eklund, H.
Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275:2151-, 2008
PubMed: 18384378 (PDB entries with the same primary citation)
DOI: 10.1111/J.1742-4658.2008.06369.X
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25070.5%2.2%4.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report